RS22B_YEAST - dbPTM
RS22B_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RS22B_YEAST
UniProt AC Q3E7Y3
Protein Name 40S ribosomal protein S22-B {ECO:0000303|PubMed:9559554}
Gene Name RPS22B {ECO:0000303|PubMed:9559554}
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 130
Subcellular Localization Cytoplasm .
Protein Description Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel..
Protein Sequence MTRSSVLADALNAINNAEKTGKRQVLLRPSSKVIIKFLQVMQKHGYIGEFEYIDDHRSGKIVVQLNGRLNKCGVISPRFNVKIGDIEKWTANLLPARQFGYVILTTSAGIMDHEEARRKHVSGKILGFVY
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MTRSSVLAD
------CCHHHHHHH
38.9822369663
4Phosphorylation----MTRSSVLADAL
----CCHHHHHHHHH
18.6822369663
5Phosphorylation---MTRSSVLADALN
---CCHHHHHHHHHH
20.1922369663
19UbiquitinationNAINNAEKTGKRQVL
HHHHHHHHHCCCEEE
61.2324961812
30PhosphorylationRQVLLRPSSKVIIKF
CEEEECCCHHHHHHH
36.0422369663
31PhosphorylationQVLLRPSSKVIIKFL
EEEECCCHHHHHHHH
33.3622369663
32AcetylationVLLRPSSKVIIKFLQ
EEECCCHHHHHHHHH
41.6224489116
43UbiquitinationKFLQVMQKHGYIGEF
HHHHHHHHHCCEEEE
22.3923749301
71UbiquitinationQLNGRLNKCGVISPR
EECCEECCCEEECCC
36.6423749301
88UbiquitinationVKIGDIEKWTANLLP
EEECCHHHHHHHCCC
50.6123749301
119UbiquitinationDHEEARRKHVSGKIL
CHHHHHHHHCCCCCC
42.6922817900
124UbiquitinationRRKHVSGKILGFVY-
HHHHCCCCCCEEEC-
27.5322817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RS22B_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RS22B_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RS22B_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GPB2_YEASTGPB2genetic
20093466
YBC9_YEASTYBL029Wgenetic
20093466
BEM1_YEASTBEM1genetic
20093466
SUL1_YEASTSUL1genetic
20093466
VAC17_YEASTVAC17genetic
20093466
MRC1_YEASTMRC1genetic
20093466
GID7_YEASTGID7genetic
20093466
GFD2_YEASTGFD2genetic
20093466
MXR2_YEASTMXR2genetic
20093466
STE50_YEASTSTE50genetic
20093466
MAK32_YEASTMAK32genetic
20093466
MTU1_YEASTSLM3genetic
20093466
RTR2_YEASTRTR2genetic
20093466
BLM10_YEASTBLM10genetic
20093466
UBP6_YEASTUBP6genetic
20093466
CSK2B_YEASTCKB1genetic
20093466
YOR1_YEASTYOR1genetic
20093466
PDR11_YEASTPDR11genetic
20093466
MMM1_YEASTMMM1genetic
20093466
PYRE_YEASTURA5genetic
20093466
TPP1_YEASTTPP1genetic
20093466
COG5_YEASTCOG5genetic
20093466
DOM34_YEASTDOM34genetic
20093466
ENG1_YEASTDSE4genetic
20093466
SPEE_YEASTSPE3genetic
20093466
YP096_YEASTYPR096Cgenetic
20093466
AXL1_YEASTAXL1genetic
20093466
HDA3_YEASTHDA3genetic
20093466
RTC6_YEASTRTC6genetic
20691087
GPR1_YEASTGPR1genetic
27708008
VAM6_YEASTVAM6genetic
27708008
RTF1_YEASTRTF1genetic
27708008
IPYR_YEASTIPP1genetic
27708008
RRP1_YEASTRRP1genetic
27708008
ERF3_YEASTSUP35genetic
27708008
CDC1_YEASTCDC1genetic
27708008
GPI19_YEASTGPI19genetic
27708008
CCA1_YEASTCCA1genetic
27708008
ACT_YEASTACT1genetic
27708008
ATC7_YEASTNEO1genetic
27708008
PAN1_YEASTPAN1genetic
27708008
COFI_YEASTCOF1genetic
27708008
DCP2_YEASTDCP2genetic
27708008
GPB2_YEASTGPB2genetic
27708008
YBC9_YEASTYBL029Wgenetic
27708008
SNF5_YEASTSNF5genetic
27708008
STE50_YEASTSTE50genetic
27708008
MXR2_YEASTMXR2genetic
27708008
GFD2_YEASTGFD2genetic
27708008
APA1_YEASTAPA1genetic
27708008
PEX34_YEASTPEX34genetic
27708008
VAC17_YEASTVAC17genetic
27708008
MAK32_YEASTMAK32genetic
27708008
MTU1_YEASTSLM3genetic
27708008
RTR2_YEASTRTR2genetic
27708008
UBP6_YEASTUBP6genetic
27708008
CSK2B_YEASTCKB1genetic
27708008
XRN1_YEASTXRN1genetic
27708008
SDT1_YEASTSDT1genetic
27708008
YOR1_YEASTYOR1genetic
27708008
PDR11_YEASTPDR11genetic
27708008
DAL81_YEASTDAL81genetic
27708008
MRS3_YEASTMRS3genetic
27708008
MMM1_YEASTMMM1genetic
27708008
PYRE_YEASTURA5genetic
27708008
TPP1_YEASTTPP1genetic
27708008
DOM34_YEASTDOM34genetic
27708008
COG5_YEASTCOG5genetic
27708008
ENG1_YEASTDSE4genetic
27708008
ODC2_YEASTODC2genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
SPEE_YEASTSPE3genetic
27708008
YP096_YEASTYPR096Cgenetic
27708008
AXL1_YEASTAXL1genetic
27708008
HDA3_YEASTHDA3genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RS22B_YEAST

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Related Literatures of Post-Translational Modification

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