CCA1_YEAST - dbPTM
CCA1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CCA1_YEAST
UniProt AC P21269
Protein Name CCA tRNA nucleotidyltransferase, mitochondrial
Gene Name CCA1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 546
Subcellular Localization Cytoplasm. Nucleus.
Isoform Mitochondrial: Mitochondrion.
Protein Description This enzyme carries out synthesis of the tRNA CCA terminus without the direction of a template using the multiple accepting and donating subsites within its active site..
Protein Sequence MLRSTISLLMNSAAQKTMTNSNFVLNAPKITLTKVEQNICNLLNDYTDLYNQKYHNKPEPLTLRITGGWVRDKLLGQGSHDLDIAINVMSGEQFATGLNEYLQQHYAKYGAKPHNIHKIDKNPEKSKHLETATTKLFGVEVDFVNLRSEKYTELSRIPKVCFGTPEEDALRRDATLNALFYNIHKGEVEDFTKRGLQDLKDGVLRTPLPAKQTFLDDPLRVLRLIRFASRFNFTIDPEVMAEMGDPQINVAFNSKISRERVGVEMEKILVGPTPLLALQLIQRAHLENVIFFWHNDSSVVKFNEENCQDMDKINHVYNDNILNSHLKSFIELYPMFLEKLPILREKIGRSPGFQQNFILSAILSPMANLQIIGNPKKKINNLVSVTESIVKEGLKLSKNDAAVIAKTVDSICSYEEILAKFADRSQLKKSEIGIFLRNFNGEWETAHFASLSDAFLKIPKLETKKIELLFQNYNEFYSYIFDNNLNNCHELKPIVDGKQMAKLLQMKPGPWLGKINNEAIRWQFDNPTGTDQELITHLKAILPKYL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MLRSTISLLMN
----CCHHHHHHHHC		26.5721126336
5Phosphorylation---MLRSTISLLMNS
---CCHHHHHHHHCH		14.2521126336
21PhosphorylationAQKTMTNSNFVLNAP
HHHHCCCCCCCCCCC		23.6028889911
150AcetylationFVNLRSEKYTELSRI
EEECCCHHCCCHHCC		59.7322865919
328PhosphorylationILNSHLKSFIELYPM
HHHHHHHHHHHHHHH		37.5019795423
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CCA1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CCA1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CCA1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ENO2_YEASTENO2physical
11805826
UTP8_YEASTUTP8physical
17634288
SHE3_YEASTSHE3genetic
27708008
DTR1_YEASTDTR1genetic
27708008
SHG1_YEASTSHG1genetic
27708008
RV161_YEASTRVS161genetic
27708008
RT103_YEASTRTT103genetic
27708008
QCR9_YEASTQCR9genetic
27708008
SPO12_YEASTSPO12genetic
27708008
XBP1_YEASTXBP1genetic
27708008
CTK1_YEASTCTK1genetic
27708008
ORN_YEASTREX2genetic
27708008
SWI6_YEASTSWI6genetic
27708008
SIN3_YEASTSIN3genetic
27708008
YP067_YEASTYPL067Cgenetic
27708008
RPN12_YEASTRPN12genetic
27708008
CDC25_YEASTCDC25genetic
27708008
GPI12_YEASTGPI12genetic
27708008
RPC6_YEASTRPC34genetic
27708008
RPB2_YEASTRPB2genetic
27708008
MED4_YEASTMED4genetic
27708008
PRS10_YEASTRPT4genetic
27708008
MOT1_YEASTMOT1genetic
27708008
PSB5_YEASTPRE2genetic
27708008
TPS1_YEASTTPS1genetic
27708008
ARL1_YEASTARL1genetic
27708008
AIM4_YEASTAIM4genetic
27708008
ODPB_YEASTPDB1genetic
27708008
RMD9L_YEASTYBR238Cgenetic
27708008
SSH1_YEASTSSH1genetic
27708008
AGP1_YEASTAGP1genetic
27708008
YCR3_YEASTYCR023Cgenetic
27708008
RIM1_YEASTRIM1genetic
27708008
SNT1_YEASTSNT1genetic
27708008
BUD31_YEASTBUD31genetic
27708008
PAT1_YEASTPAT1genetic
27708008
BRE1_YEASTBRE1genetic
27708008
QRI7_YEASTQRI7genetic
27708008
PAR32_YEASTPAR32genetic
27708008
YD042_YEASTYDR042Cgenetic
27708008
VMS1_YEASTVMS1genetic
27708008
OCA6_YEASTOCA6genetic
27708008
PP4C_YEASTPPH3genetic
27708008
ODO2_YEASTKGD2genetic
27708008
INM2_YEASTINM2genetic
27708008
OMS1_YEASTOMS1genetic
27708008
SWR1_YEASTSWR1genetic
27708008
LSM6_YEASTLSM6genetic
27708008
GLRX2_YEASTGRX2genetic
27708008
ERV14_YEASTERV14genetic
27708008
GEP7_YEASTGEP7genetic
27708008
HUL5_YEASTHUL5genetic
27708008
XRN1_YEASTXRN1genetic
27708008
CWC26_YEASTBUD13genetic
27708008
HOS2_YEASTHOS2genetic
27708008
ENV11_YEASTENV11genetic
27708008
PHB2_YEASTPHB2genetic
27708008
TNA1_YEASTTNA1genetic
27708008
MED20_YEASTSRB2genetic
27708008
NMD2_YEASTNMD2genetic
27708008
UBA4_YEASTUBA4genetic
27708008
ATG7_YEASTATG7genetic
27708008
PTH_YEASTPTH1genetic
27708008
RPN10_YEASTRPN10genetic
27708008
FYV10_YEASTFYV10genetic
27708008
IST3_YEASTIST3genetic
27708008
GSH1_YEASTGSH1genetic
27708008
LSM1_YEASTLSM1genetic
27708008
ILM1_YEASTILM1genetic
27708008
YJ90_YEASTYJR120Wgenetic
27708008
HAP4_YEASTHAP4genetic
27708008
COXM1_YEASTCMC1genetic
27708008
DBR1_YEASTDBR1genetic
27708008
ELF1_YEASTELF1genetic
27708008
DCOR_YEASTSPE1genetic
27708008
POC2_YEASTADD66genetic
27708008
MEH1_YEASTMEH1genetic
27708008
SA190_YEASTSAP190genetic
27708008
SET3_YEASTSET3genetic
27708008
FRA1_YEASTFRA1genetic
27708008
POC3_YEASTIRC25genetic
27708008
COX12_YEASTCOX12genetic
27708008
RL22A_YEASTRPL22Agenetic
27708008
YL149_YEASTYLR149Cgenetic
27708008
EIF3J_YEASTHCR1genetic
27708008
LIPB_YEASTLIP2genetic
27708008
ARV1_YEASTARV1genetic
27708008
NKP2_YEASTNKP2genetic
27708008
ELO3_YEASTELO3genetic
27708008
VID22_YEASTVID22genetic
27708008
COX8_YEASTCOX8genetic
27708008
CDC73_YEASTCDC73genetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
RCF1_YEASTRCF1genetic
27708008
VPS71_YEASTVPS71genetic
27708008
ATP18_YEASTATP18genetic
27708008
AIM34_YEASTAIM34genetic
27708008
MSS1_YEASTMSS1genetic
27708008
NAM7_YEASTNAM7genetic
27708008
MUB1_YEASTMUB1genetic
27708008
SKY1_YEASTSKY1genetic
27708008
COX7_YEASTCOX7genetic
27708008
GAS1_YEASTGAS1genetic
27708008
PET8_YEASTPET8genetic
27708008
APP1_YEASTAPP1genetic
27708008
RTG1_YEASTRTG1genetic
27708008
HST1_YEASTHST1genetic
27708008
ADH1_YEASTADH1genetic
27708008
RFM1_YEASTRFM1genetic
27708008
MRS2_YEASTMRS2genetic
27708008
YP014_YEASTYPL014Wgenetic
27708008
LGE1_YEASTLGE1genetic
27708008
LPE10_YEASTMFM1genetic
27708008
POC4_YEASTPOC4genetic
27708008
ATG5_YEASTATG5genetic
27708008
PET20_YEASTPET20genetic
27708008
COX10_YEASTCOX10genetic
27708008
MED1_YEASTMED1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CCA1_YEAST

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory