| UniProt ID | QRI7_YEAST | |
|---|---|---|
| UniProt AC | P43122 | |
| Protein Name | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03179} | |
| Gene Name | QRI7 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 407 | |
| Subcellular Localization | Mitochondrion . | |
| Protein Description | Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.. | |
| Protein Sequence | MISIKGTGRFLLDNYRIWQRRAFNRPIQLRKGYKVLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESNAREGIDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAREMEKFINQDINDQDFALKLEMPSPLKNSASKRNMLSFSFSAFITALRTNLTKLGKTEIQELPEREIRSIAYQVQESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRTKLETELGTLNSTSFFNFYYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICPIRQWPLNDLLSVDGWRTDQL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 328 | Phosphorylation | VCSGGVSSNQRLRTK HHCCCCCHHHHHHHH | 34.28 | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of QRI7_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of QRI7_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of QRI7_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| QRI7_YEAST | QRI7 | physical | 25084372 | |
| QRI7_YEAST | QRI7 | physical | 23620299 | |
| FKS2_YEAST | GSC2 | genetic | 27708008 | |
| PPT1_YEAST | PPT1 | genetic | 27708008 | |
| RL7B_YEAST | RPL7B | genetic | 27708008 | |
| MED8_YEAST | MED8 | genetic | 27708008 | |
| SNU56_YEAST | SNU56 | genetic | 27708008 | |
| RSC3_YEAST | RSC3 | genetic | 27708008 | |
| SEC39_YEAST | SEC39 | genetic | 27708008 | |
| RTR1_YEAST | RTR1 | genetic | 27708008 | |
| MED20_YEAST | SRB2 | genetic | 27708008 | |
| PYRD_YEAST | URA1 | genetic | 27708008 | |
| UPS2_YEAST | UPS2 | genetic | 27708008 | |
| VIP1_YEAST | VIP1 | genetic | 27708008 | |
| MDM1_YEAST | MDM1 | genetic | 27708008 | |
| YMX7_YEAST | YMR087W | genetic | 27708008 | |
| GCSP_YEAST | GCV2 | genetic | 27708008 | |
| EOS1_YEAST | EOS1 | genetic | 27708008 | |
| MDM38_YEAST | MDM38 | genetic | 27708008 | |
| PEX15_YEAST | PEX15 | genetic | 27708008 | |
| MET22_YEAST | MET22 | genetic | 27708008 | |
| IDH2_YEAST | IDH2 | genetic | 27708008 | |
| SFL1_YEAST | SFL1 | genetic | 27708008 | |
| MGR2_YEAST | MGR2 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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