QRI7_YEAST - dbPTM
QRI7_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID QRI7_YEAST
UniProt AC P43122
Protein Name tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03179}
Gene Name QRI7
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 407
Subcellular Localization Mitochondrion .
Protein Description Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance..
Protein Sequence MISIKGTGRFLLDNYRIWQRRAFNRPIQLRKGYKVLAIETSCDDTCVSVLDRFSKSAAPNVLANLKDTLDSIDEGGIIPTKAHIHHQARIGPLTERALIESNAREGIDLICVTRGPGMPGSLSGGLDFAKGLAVAWNKPLIGVHHMLGHLLIPRMGTNGKVPQFPFVSLLVSGGHTTFVLSRAIDDHEILCDTIDIAVGDSLDKCGRELGFKGTMIAREMEKFINQDINDQDFALKLEMPSPLKNSASKRNMLSFSFSAFITALRTNLTKLGKTEIQELPEREIRSIAYQVQESVFDHIINKLKHVLKSQPEKFKNVREFVCSGGVSSNQRLRTKLETELGTLNSTSFFNFYYPPMDLCSDNSIMIGWAGIEIWESLRLVSDLDICPIRQWPLNDLLSVDGWRTDQL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
328PhosphorylationVCSGGVSSNQRLRTK
HHCCCCCHHHHHHHH
34.2827017623

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of QRI7_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of QRI7_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of QRI7_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
QRI7_YEASTQRI7physical
25084372
QRI7_YEASTQRI7physical
23620299
FKS2_YEASTGSC2genetic
27708008
PPT1_YEASTPPT1genetic
27708008
RL7B_YEASTRPL7Bgenetic
27708008
MED8_YEASTMED8genetic
27708008
SNU56_YEASTSNU56genetic
27708008
RSC3_YEASTRSC3genetic
27708008
SEC39_YEASTSEC39genetic
27708008
RTR1_YEASTRTR1genetic
27708008
MED20_YEASTSRB2genetic
27708008
PYRD_YEASTURA1genetic
27708008
UPS2_YEASTUPS2genetic
27708008
VIP1_YEASTVIP1genetic
27708008
MDM1_YEASTMDM1genetic
27708008
YMX7_YEASTYMR087Wgenetic
27708008
GCSP_YEASTGCV2genetic
27708008
EOS1_YEASTEOS1genetic
27708008
MDM38_YEASTMDM38genetic
27708008
PEX15_YEASTPEX15genetic
27708008
MET22_YEASTMET22genetic
27708008
IDH2_YEASTIDH2genetic
27708008
SFL1_YEASTSFL1genetic
27708008
MGR2_YEASTMGR2genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of QRI7_YEAST

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Related Literatures of Post-Translational Modification

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