| UniProt ID | MDM38_YEAST | |
|---|---|---|
| UniProt AC | Q08179 | |
| Protein Name | Mitochondrial distribution and morphology protein 38 {ECO:0000303|PubMed:11907266} | |
| Gene Name | MDM38 {ECO:0000303|PubMed:11907266} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 573 | |
| Subcellular Localization |
Mitochondrion inner membrane Single-pass membrane protein . |
|
| Protein Description | Involved in mitochondrial potassium homeostasis through the mitochondrial K(+)/H(+) exchange regulation. [PubMed: 11907266] | |
| Protein Sequence | MLNFASRASCVTRRQASLYFVKNQGPRLIASTIPSCHWPLRAQGVQPNYPLSLRFYSTDKSKSVTKPVAPTSTDAPAKPKETLMVKVKHALKHYANGTKLLGYEIKVSTKLLIKFAQGYELSRRERNQLRRTMGDVFRLIPFSAFLIIPFAELFLPFALKLFPNLLPSTYESGKDKQAKRNKLIEIRKKTSEFLHETLEESNLITYNTIENAEKKQKFLNFFRKLYSAKEGKIMTFQHDEISAIAQMFKNDSVLDNLSRPQLAAMSKFMSLRPFGNDNMLRYQIRSKLKDIMNDDKTIDYEGVESLSQEELYQACVSRGMKAYGVSKEDLVDNLKVWLELRLRQKIPSVLMVLSSTFTFGGLPKENYSKAFSPLAEKKETKSKYDDLLDLYYDGILQVLSSIPDPVYNVAKLDVSESKSSAAETEAEKQVAEKKIKTEEKPEETAIPKEEATAKESVIATTASAVTPKLVVVNEKAETAKTEEISQEKENAEPTDSAEATEAEEKKTSDDNEFKLNVLKEQEELIKKEEEEAKQRASREHVPDDINLDEEEEAKSVPPIPADQAAKTFVIKKD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 63 | Phosphorylation | YSTDKSKSVTKPVAP EECCCCCCCCCCCCC | 41.95 | 28889911 | |
| 217 | Acetylation | ENAEKKQKFLNFFRK CCHHHHHHHHHHHHH | 61.78 | 24489116 | |
| 321 | Acetylation | ACVSRGMKAYGVSKE HHHHHCHHHHCCCHH | 41.08 | 24489116 | |
| 327 | Acetylation | MKAYGVSKEDLVDNL HHHHCCCHHHHHHHH | 53.49 | 24489116 | |
| 369 | Acetylation | LPKENYSKAFSPLAE CCHHHCHHCCCCHHH | 42.99 | 24489116 | |
| 372 | Phosphorylation | ENYSKAFSPLAEKKE HHCHHCCCCHHHCHH | 24.70 | 30377154 | |
| 418 | Ubiquitination | KLDVSESKSSAAETE ECCCCCCCCCHHHHH | 44.36 | 23749301 | |
| 428 | Ubiquitination | AAETEAEKQVAEKKI HHHHHHHHHHHHHHC | 58.06 | 23749301 | |
| 437 | Phosphorylation | VAEKKIKTEEKPEET HHHHHCCCCCCCCCC | 53.50 | 19823750 | |
| 444 | Phosphorylation | TEEKPEETAIPKEEA CCCCCCCCCCCHHHH | 28.38 | 19795423 | |
| 475 | Acetylation | KLVVVNEKAETAKTE EEEEECCCHHHCCHH | 46.44 | 24489116 | |
| 488 | Ubiquitination | TEEISQEKENAEPTD HHHHHHHHHHCCCCC | 48.94 | 23749301 | |
| 488 | Acetylation | TEEISQEKENAEPTD HHHHHHHHHHCCCCC | 48.94 | 24489116 | |
| 555 | Phosphorylation | DEEEEAKSVPPIPAD CHHHHHHCCCCCCCC | 47.07 | 29734811 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MDM38_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MDM38_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MDM38_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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