NAM9_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: NAM9_YEAST
• UniProt AC: P27929
• Protein Name: 37S ribosomal protein NAM9, mitochondrial
• Gene Name: NAM9
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 486
• Subcellular Localization: Mitochondrion . Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner memb
• Protein Description: Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane..
• Protein Sequence: MPRKANLLKSLARGRVRTSFNKYNLFNLYKKGGVDLKSKSLYQQKWTAKQETRAYHGEHLTEKRWQTVFKPKLDSVAQLDASLRGGEIKETPFLLQTFAVLEKRLDFALFRAMFASSVRQARQFILHGNVRVNGVKIKHPSYTLKPGDMFSVKPDKVLEALGAKKPSFQEALKIDKTQIVLWNKYVKEAKTEPKEVWEKKLENFEKMSDSNPKKLQFQEFLRQYNKNLESQQYNALKGCTQEGILRKLLNVEKEIGKSNNEPLSIDELKQGLPEIQDSQLLESLNNAYQEFFKSGEIRREIISKCQPDELISLATEMMNPNETTKKELSDGAKSALRSGKRIIAESVKLWTKNITDHFKTRMSDISDGSLTFDPKWAKNLKYHDPIKLSELEGDEPKARKLINLPWQKNYVYGRQDPKKPFFTPWKPRPFLSPFAILPHHLEISFKTCHAVYLRDPVARPGQSEVISPFDVPVHERAYMYYLRNGK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
151	Phosphorylation	LKPGDMFSVKPDKVL CCCCCCEEECHHHHH	23.69	27017623
230	Phosphorylation	QYNKNLESQQYNALK HHHHCHHHHHHHHHC	26.25	27017623
293	Ubiquitination	NAYQEFFKSGEIRRE HHHHHHHHCCHHHHH	63.97	19722269
363	Phosphorylation	DHFKTRMSDISDGSL HHHHHCHHHCCCCCC	28.62	22369663
366	Phosphorylation	KTRMSDISDGSLTFD HHCHHHCCCCCCCCC	40.69	22369663
369	Phosphorylation	MSDISDGSLTFDPKW HHHCCCCCCCCCHHH	29.26	22369663
371	Phosphorylation	DISDGSLTFDPKWAK HCCCCCCCCCHHHHH	27.91	22369663
400	Acetylation	GDEPKARKLINLPWQ CCCCCHHHHHCCCCH	59.59	24489116
412	Phosphorylation	PWQKNYVYGRQDPKK CCHHCCCCCCCCCCC	9.02	19684113

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of NAM9_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of NAM9_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of NAM9_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HS104_YEAST	HSP104	genetic	10982839
GDS1_YEAST	GDS1	genetic	8750239
RT09_YEAST	MRPS9	physical	16554755
RT10_YEAST	RSM10	physical	16554755
RT24_YEAST	RSM24	physical	16554755
RT01_YEAST	MRP1	physical	16554755
RSM28_YEAST	RSM28	physical	16554755
RT23_YEAST	RSM23	physical	16554755
RT13_YEAST	MRP13	physical	16554755
RT04_YEAST	MRP4	physical	16554755
RT06_YEAST	MRP17	physical	16554755
RTPT_YEAST	PET123	physical	16554755
RT51_YEAST	MRP51	physical	16554755
RT35_YEAST	MRPS35	physical	16429126
MAM33_YEAST	MAM33	physical	16429126
SLA1_YEAST	SLA1	genetic	21987634
CSG2_YEAST	CSG2	genetic	21987634
ERG4_YEAST	ERG4	genetic	21987634
RT106_YEAST	RTT106	genetic	21987634
YNU8_YEAST	YNL208W	genetic	21987634
VPS27_YEAST	VPS27	genetic	21987634
GEP3_YEAST	GEP3	genetic	21987634
MDL2_YEAST	MDL2	genetic	21987634

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.