MDL2_YEAST - dbPTM
MDL2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MDL2_YEAST
UniProt AC P33311
Protein Name ATP-dependent permease MDL2, mitochondrial
Gene Name MDL2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 773
Subcellular Localization Mitochondrion inner membrane
Multi-pass membrane protein .
Protein Description
Protein Sequence MLNGRLPLLRLGICRNMLSRPRLAKLPSIRFRSLVTPSSSQLIPLSRLCLRSPAVGKSLILQSFRCNSSKTVPETSLPSASPISKGSARSAHAKEQSKTDDYKDIIRLFMLAKRDWKLLLTAILLLTISCSIGMSIPKVIGIVLDTLKTSSGSDFFDLKIPIFSLPLYEFLSFFTVALLIGCAANFGRFILLRILSERVVARLRANVIKKTLHQDAEFFDNHKVGDLISRLGSDAYVVSRSMTQKVSDGVKALICGVVGVGMMCSLSPQLSILLLFFTPPVLFSASVFGKQIRNTSKDLQEATGQLTRVAEEQLSGIKTVQSFVAEGNELSRYNVAIRDIFQVGKTAAFTNAKFFTTTSLLGDLSFLTVLAYGSYLVLQSQLSIGDLTAFMLYTEYTGNAVFGLSTFYSEIMQGAGAASRLFELTDRKPSISPTVGHKYKPDRGVIEFKDVSFSYPTRPSVQIFKNLNFKIAPGSSVCIVGPSGRGKSTIALLLLRYYNPTTGTITIDNQDISKLNCKSLRRHIGIVQQEPVLMSGTIRDNITYGLTYTPTKEEIRSVAKQCFCHNFITKFPNTYDTVIGPHGTLLSGGQKQRIAIARALIKKPTILILDEATSALDVESEGAINYTFGQLMKSKSMTIVSIAHRLSTIRRSENVIVLGHDGSVVEMGKFKELYANPTSALSQLLNEKAAPGPSDQQLQIEKVIEKEDLNESKEHDDQKKDDNDDNDNNHDNDSNNQSPETKDNNSDDIEKSVEHLLKDAAKEANPIKITPQP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
25AcetylationLSRPRLAKLPSIRFR
HCCHHHCCCCCCCEE		66.5724489116
28PhosphorylationPRLAKLPSIRFRSLV
HHHCCCCCCCEECCC		36.5127017623
90PhosphorylationISKGSARSAHAKEQS
CCCCCCCHHHHHHHH		24.9128889911
97PhosphorylationSAHAKEQSKTDDYKD
HHHHHHHHCCCCHHH		38.3227017623
99PhosphorylationHAKEQSKTDDYKDII
HHHHHHCCCCHHHHH		39.0727017623
223AcetylationAEFFDNHKVGDLISR
HHHHCCCCHHHHHHH		54.9224489116
552AcetylationGLTYTPTKEEIRSVA
EEEECCCHHHHHHHH		55.3324489116
641PhosphorylationSKSMTIVSIAHRLST
CCCCCHHHHHHHHHH		15.3727017623
746PhosphorylationPETKDNNSDDIEKSV
CCCCCCCHHHHHHHH		42.8027017623
752PhosphorylationNSDDIEKSVEHLLKD
CHHHHHHHHHHHHHH		21.6827017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MDL2_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MDL2_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MDL2_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SWD1_YEASTSWD1genetic
20093466
GPX2_YEASTGPX2genetic
20093466
YD183_YEASTYDL183Cgenetic
20093466
HOSC_YEASTLYS20genetic
20093466
ATG9_YEASTATG9genetic
20093466
AIM7_YEASTAIM7genetic
20093466
RT31_YEASTYMR31genetic
20093466
CSK2B_YEASTCKB1genetic
20093466
RS23A_YEASTRPS23Agenetic
20093466
RS23B_YEASTRPS23Agenetic
20093466
FLX1_YEASTFLX1genetic
20093466
CSN11_YEASTPCI8genetic
20093466
MNT3_YEASTMNT3genetic
20093466
URM1_YEASTURM1genetic
20093466
IST3_YEASTIST3genetic
20093466
ASF1_YEASTASF1genetic
20093466
AP2B_YEASTAPL1genetic
20093466
RAD26_YEASTRAD26genetic
20093466
DPOD3_YEASTPOL32genetic
20093466
ELM1_YEASTELM1genetic
20093466
RS30A_YEASTRPS30Agenetic
20093466
RS30B_YEASTRPS30Agenetic
20093466
MSC1_YEASTMSC1genetic
20093466
SPC2_YEASTSPC2genetic
20093466
SAP30_YEASTSAP30genetic
20093466
SNAPN_YEASTSNN1genetic
20093466
YPK9_YEASTYPK9genetic
20093466
MGR2_YEASTMGR2genetic
20093466
ELO3_YEASTELO3genetic
22808036
MRM2_YEASTMRM2genetic
27708008
CDK1_YEASTCDC28genetic
27708008
ACT_YEASTACT1genetic
27708008
CDC12_YEASTCDC12genetic
27708008
MOB1_YEASTMOB1genetic
27708008
PAN1_YEASTPAN1genetic
27708008
HSP77_YEASTSSC1genetic
27708008
FIP1_YEASTFIP1genetic
27708008
RNA1_YEASTRNA1genetic
27708008
DPOA_YEASTPOL1genetic
27708008
RIM1_YEASTRIM1genetic
27708008
IMG2_YEASTIMG2genetic
27708008
MED20_YEASTSRB2genetic
27708008
MNT3_YEASTMNT3genetic
27708008
FLX1_YEASTFLX1genetic
27708008
IST3_YEASTIST3genetic
27708008
ASF1_YEASTASF1genetic
27708008
SPC2_YEASTSPC2genetic
27708008
LSM7_YEASTLSM7genetic
27708008
COQ2_YEASTCOQ2genetic
27708008
COQ7_YEASTCAT5genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MDL2_YEAST

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Related Literatures of Post-Translational Modification

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