dbPTM

MNT3_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MNT3_YEAST
UniProt AC	P40549
Protein Name	Alpha-1,3-mannosyltransferase MNT3
Gene Name	MNT3
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	630
Subcellular Localization	Golgi apparatus membrane Single-pass type II membrane protein .
Protein Description	Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans..
Protein Sequence	MLKSLKSRRLILKRLVTLLLSLFFSYLIFSASRNVTSSNKLNNHASERTAVESSAFNWIEKRQHQVRSENLMNRLSAYFLPFLSRSSHKERVLLRQLGNNEIAKSDKCRYIFEVLYKIDPDWDNAQTAKFYNVDGVDNTLASLLGERLRSYDYCFLSGQLDPTAIFANSTVNPHDLQNRMFPFLKKINEESKTVMWPIITDMTTGEAVPAPEVDMESSNFNGNFWSNWNRLSKGRGFVLTIAEKDVPLFLKQLKVMEFSKNELPFQIVSTGNELSAESIAKISETAKETEQRVYLVDCSTVLDTNFANTYISFFQNKWVATLFNTFEEYILLDADVVPFVGSDYFFDSPSYRESGILLFKDRVMENEQTFQYCIEMLNEVEPSAQERRFIGSRLVFDSSLPFSSETSEEASVYYNFFKKLRLHHVDSGLVVVNKLEKLNGLLMSFMLNLDGKLQRCVYGDKEIFWLGQLYAGQDYSINPVDGSIIGPVNEEPENDDGHKSGMYYICSTQIAHSDSKNRLLWVNGGLKTCKISNSAEDDFGREPEYFKSRYGDISKLKRIYDASLNVEGLIVPDVSVHPWMQIKECSNYMYCAYATGDGHTNSELDEGRLITFTEKELRYINDISRTWNAN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
34	N-linked_Glycosylation	LIFSASRNVTSSNKL HHHHHHCCCCCCCCC	38.63	-
168	N-linked_Glycosylation	DPTAIFANSTVNPHD CCCEEECCCCCCHHH	27.71	-
615	Acetylation	RLITFTEKELRYIND CEEEEEHHHHHHHHH	60.02	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MNT3_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MNT3_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MNT3_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EF1A_YEAST	TEF2	physical	22940862
HSP71_YEAST	SSA1	physical	22940862
HSP72_YEAST	SSA2	physical	22940862
SSB1_YEAST	SSB1	physical	22940862
SMI1_YEAST	SMI1	genetic	23891562
RTG3_YEAST	RTG3	genetic	27708008
SWC5_YEAST	SWC5	genetic	27708008
CHK1_YEAST	CHK1	genetic	27708008
RAD4_YEAST	RAD4	genetic	27708008
PTK2_YEAST	PTK2	genetic	27708008
DOHH_YEAST	LIA1	genetic	27708008
CSN12_YEAST	YJR084W	genetic	27708008
AIM26_YEAST	AIM26	genetic	27708008
CTK1_YEAST	CTK1	genetic	27708008
PSR1_YEAST	PSR1	genetic	27708008
ENV10_YEAST	ENV10	genetic	27708008
SWI6_YEAST	SWI6	genetic	27708008
RS30A_YEAST	RPS30A	genetic	27708008
RS30B_YEAST	RPS30A	genetic	27708008
VPS38_YEAST	VPS38	genetic	27708008
ROM2_YEAST	ROM2	genetic	27708008
VAC14_YEAST	VAC14	genetic	27708008
OST6_YEAST	OST6	genetic	27708008
NU188_YEAST	NUP188	genetic	27708008
RAD14_YEAST	RAD14	genetic	27708008
BUL1_YEAST	BUL1	genetic	27708008
JNM1_YEAST	JNM1	genetic	27708008
SWS2_YEAST	SWS2	genetic	27708008
EAF7_YEAST	EAF7	genetic	27708008
ARE2_YEAST	ARE2	genetic	27708008
INO4_YEAST	INO4	genetic	27708008
RUD3_YEAST	RUD3	genetic	27708008
VPH1_YEAST	VPH1	genetic	27708008
RAD1_YEAST	RAD1	genetic	27708008
GGPPS_YEAST	BTS1	genetic	27708008
COX10_YEAST	COX10	genetic	27708008
NEW1_YEAST	NEW1	genetic	27708008
FPS1_YEAST	FPS1	genetic	29674565
MOG1_YEAST	MOG1	genetic	29674565
EMI1_YEAST	EMI1	genetic	29674565
MSH2_YEAST	MSH2	genetic	29674565
YP066_YEAST	RGL1	genetic	29674565

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MNT3_YEAST

Related Literatures of Post-Translational Modification