COX10_YEAST - dbPTM
COX10_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COX10_YEAST
UniProt AC P21592
Protein Name Protoheme IX farnesyltransferase, mitochondrial
Gene Name COX10
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 462
Subcellular Localization Mitochondrion membrane
Multi-pass membrane protein.
Protein Description Converts protoheme IX and farnesyl diphosphate to heme O..
Protein Sequence MSYFPRTYAHLMRNVLAHNKGNIYLQIGTQLHDTQIKIRFNGVRYISRNHGGKQQHINTAPIEFTPNFGYGDRTSNCNKKVESTAMKTLRCTDDISTSSGSEATTDASTQLPFNVKLVDPMVRKSKRPSHAISEGLNMKTLKKKVIMPYLQLTKPRLTILVMLSAICSYALSPYPASVNELLCLTVGTTLCSGSANAINMGREPEFDRQMVRTQARPVVRGDVTPTQAFEFAALIGTLGVSILYFGVNPTVAILGASNIALYGWAYTSMKRKHIINTWLGALVGMVPPLMGWAAASPLSHPGSWCLAGLLFAWQFPHFNTLSHNIRNEYKNAGYVMTAWKNPLLNARVSLRYSILMFPLCFGLSYFNITDWYYQIDSGLINAWLTFWAFKFYWQQRINYSAKTLKDNVKFNKGLSVANIYARKTFMASVLHLPAILILAIIHKKGRWDWIYPGEAKRPQERF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of COX10_YEAST !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COX10_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of COX10_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COX10_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
MSS51_YEASTMSS51genetic
17882260
COX15_YEASTCOX15physical
19841065
PMT2_YEASTPMT2genetic
20093466
DEP1_YEASTDEP1genetic
20093466
ERP2_YEASTERP2genetic
20093466
RXT2_YEASTRXT2genetic
20093466
RS6A_YEASTRPS6Bgenetic
20093466
RS6B_YEASTRPS6Bgenetic
20093466
SNT1_YEASTSNT1genetic
20093466
KIN82_YEASTKIN82genetic
20093466
MRH1_YEASTMRH1genetic
20093466
PAA1_YEASTPAA1genetic
20093466
PP4C_YEASTPPH3genetic
20093466
UBC13_YEASTUBC13genetic
20093466
EMI1_YEASTEMI1genetic
20093466
PTP3_YEASTPTP3genetic
20093466
ECM32_YEASTECM32genetic
20093466
MMS2_YEASTMMS2genetic
20093466
KA122_YEASTKAP122genetic
20093466
ENV11_YEASTENV11genetic
20093466
SLX9_YEASTSLX9genetic
20093466
GYP2_YEASTMDR1genetic
20093466
CGS6_YEASTCLB6genetic
20093466
ENO1_YEASTENO1genetic
20093466
NPR3_YEASTNPR3genetic
20093466
FYV4_YEASTFYV4genetic
20093466
FMC1_YEASTFMC1genetic
20093466
FYV10_YEASTFYV10genetic
20093466
MHP1_YEASTMHP1genetic
20093466
EMC2_YEASTEMC2genetic
20093466
YJ90_YEASTYJR120Wgenetic
20093466
LTHAD_YEASTSRY1genetic
20093466
VPS24_YEASTVPS24genetic
20093466
RGT1_YEASTRGT1genetic
20093466
DS1P2_YEASTYSR3genetic
20093466
PSR1_YEASTPSR1genetic
20093466
SSK1_YEASTSSK1genetic
20093466
BRE2_YEASTBRE2genetic
20093466
SMF3_YEASTSMF3genetic
20093466
COX12_YEASTCOX12genetic
20093466
YL050_YEASTYLR050Cgenetic
20093466
SRL2_YEASTSRL2genetic
20093466
SRN2_YEASTSRN2genetic
20093466
ACE2_YEASTACE2genetic
20093466
AP1S1_YEASTAPS1genetic
20093466
YL225_YEASTYLR225Cgenetic
20093466
THI7_YEASTTHI7genetic
20093466
VAC14_YEASTVAC14genetic
20093466
RS29A_YEASTRPS29Agenetic
20093466
ATP10_YEASTATP10genetic
20093466
RPN13_YEASTRPN13genetic
20093466
ATP18_YEASTATP18genetic
20093466
GAL80_YEASTGAL80genetic
20093466
USA1_YEASTUSA1genetic
20093466
ERG6_YEASTERG6genetic
20093466
UBC7_YEASTUBC7genetic
20093466
RCO1_YEASTRCO1genetic
20093466
SIP5_YEASTSIP5genetic
20093466
AEP2_YEASTAEP2genetic
20093466
FAR11_YEASTFAR11genetic
20093466
PHO23_YEASTPHO23genetic
20093466
TOM7_YEASTTOM7genetic
20093466
IPB2_YEASTPBI2genetic
20093466
ATP23_YEASTATP23genetic
20093466
YPQ1_YEASTYPQ1genetic
20093466
INP54_YEASTINP54genetic
20093466
YO13A_YEASTYOL013W-Agenetic
20093466
SIN3_YEASTSIN3genetic
20093466
SGT2_YEASTSGT2genetic
20093466
YO012_YEASTYOR012Wgenetic
20093466
WHI5_YEASTWHI5genetic
20093466
LEU9_YEASTLEU9genetic
20093466
YOR31_YEASTYOR131Cgenetic
20093466
DGK1_YEASTDGK1genetic
20093466
PDE2_YEASTPDE2genetic
20093466
ETFA_YEASTAIM45genetic
20093466
CSR2_YEASTCSR2genetic
20093466
ROX1_YEASTROX1genetic
20093466
PPAL_YEASTLTP1genetic
20093466
HPA2_YEASTHPA2genetic
20093466
DCOR_YEASTSPE1genetic
21623372
SPEE_YEASTSPE3genetic
21623372
COX9_YEASTCOX9genetic
21623372
AATM_YEASTAAT1genetic
21623372
TPS1_YEASTTPS1genetic
21623372
INO1_YEASTINO1genetic
21623372
QCR7_YEASTQCR7genetic
21623372
THDH_YEASTILV1genetic
21623372
PHSG_YEASTGPH1genetic
21623372
GLT1_YEASTGLT1genetic
21623372
QCR8_YEASTQCR8genetic
21623372
ATPA_YEASTATP1genetic
21623372
MAL31_YEASTMAL31genetic
21623372
FOLE_YEASTMET7genetic
21623372
ATPO_YEASTATP5genetic
21623372
ATPK_YEASTATP17genetic
21623372
PP2C1_YEASTPTC1genetic
27708008
MNN10_YEASTMNN10genetic
27708008
CWH41_YEASTCWH41genetic
27708008
FIS1_YEASTFIS1genetic
27708008
MDV1_YEASTMDV1genetic
27708008
CBT1_YEASTCBT1genetic
27708008
DNM1_YEASTDNM1genetic
27708008
AVL9_YEASTAVL9genetic
27708008
COA4_YEASTCOA4genetic
27708008
ELP1_YEASTIKI3genetic
27708008
VAC14_YEASTVAC14genetic
27708008
HDA1_YEASTHDA1genetic
27708008
YNE6_YEASTYNL046Wgenetic
27708008
SWS2_YEASTSWS2genetic
27708008
THI20_YEASTTHI20genetic
27708008
ASE1_YEASTASE1genetic
27708008
CDC24_YEASTCDC24genetic
27708008
IPYR_YEASTIPP1genetic
27708008
TIM22_YEASTTIM22genetic
27708008
CDC1_YEASTCDC1genetic
27708008
SRPR_YEASTSRP101genetic
27708008
PSB3_YEASTPUP3genetic
27708008
RSP5_YEASTRSP5genetic
27708008
COG3_YEASTCOG3genetic
27708008
CCA1_YEASTCCA1genetic
27708008
MOB2_YEASTMOB2genetic
27708008
YPT1_YEASTYPT1genetic
27708008
TIM16_YEASTPAM16genetic
27708008
TAD3_YEASTTAD3genetic
27708008
APC5_YEASTAPC5genetic
27708008
PRS10_YEASTRPT4genetic
27708008
ERP2_YEASTERP2genetic
27708008
DEP1_YEASTDEP1genetic
27708008
GPB2_YEASTGPB2genetic
27708008
YBF5_YEASTYBL055Cgenetic
27708008
RXT2_YEASTRXT2genetic
27708008
YBY7_YEASTYBR137Wgenetic
27708008
HPC2_YEASTHPC2genetic
27708008
PEX34_YEASTPEX34genetic
27708008
CISY2_YEASTCIT2genetic
27708008
RV161_YEASTRVS161genetic
27708008
SNT1_YEASTSNT1genetic
27708008
FUB1_YEASTFUB1genetic
27708008
PAA1_YEASTPAA1genetic
27708008
PP4C_YEASTPPH3genetic
27708008
UBC13_YEASTUBC13genetic
27708008
TMS1_YEASTTMS1genetic
27708008
INO2_YEASTINO2genetic
27708008
YD210_YEASTYDR210Wgenetic
27708008
PEX10_YEASTPEX10genetic
27708008
PMP3_YEASTPMP3genetic
27708008
IPK1_YEASTIPK1genetic
27708008
PDR15_YEASTPDR15genetic
27708008
VPS60_YEASTVPS60genetic
27708008
SPO73_YEASTSPO73genetic
27708008
GIP2_YEASTGIP2genetic
27708008
YFF2_YEASTYFL052Wgenetic
27708008
RL2A_YEASTRPL2Agenetic
27708008
RL2B_YEASTRPL2Agenetic
27708008
PRM8_YEASTPRM8genetic
27708008
MPC1_YEASTMPC1genetic
27708008
MMS2_YEASTMMS2genetic
27708008
AAKG_YEASTSNF4genetic
27708008
RAD54_YEASTRAD54genetic
27708008
ENV11_YEASTENV11genetic
27708008
RL11B_YEASTRPL11Bgenetic
27708008
GYP2_YEASTMDR1genetic
27708008
HGH1_YEASTHGH1genetic
27708008
BGL2_YEASTBGL2genetic
27708008
NPR3_YEASTNPR3genetic
27708008
SMF2_YEASTSMF2genetic
27708008
VHR1_YEASTVHR1genetic
27708008
SDS3_YEASTSDS3genetic
27708008
FYV10_YEASTFYV10genetic
27708008
FMC1_YEASTFMC1genetic
27708008
PRM5_YEASTPRM5genetic
27708008
IMPX_YEASTIMP2genetic
27708008
MAD2_YEASTMAD2genetic
27708008
GSH1_YEASTGSH1genetic
27708008
PBS2_YEASTPBS2genetic
27708008
SFH5_YEASTSFH5genetic
27708008
SET2_YEASTSET2genetic
27708008
PTK2_YEASTPTK2genetic
27708008
CBF1_YEASTCBF1genetic
27708008
RGT1_YEASTRGT1genetic
27708008
VPS24_YEASTVPS24genetic
27708008
CWP2_YEASTCWP2genetic
27708008
DCOR_YEASTSPE1genetic
27708008
DID2_YEASTDID2genetic
27708008
BAS1_YEASTBAS1genetic
27708008
PSR1_YEASTPSR1genetic
27708008
RL8B_YEASTRPL8Bgenetic
27708008
SSK1_YEASTSSK1genetic
27708008
PPR1_YEASTPPR1genetic
27708008
SMF3_YEASTSMF3genetic
27708008
RL22A_YEASTRPL22Agenetic
27708008
SRL2_YEASTSRL2genetic
27708008
SRN2_YEASTSRN2genetic
27708008
ACE2_YEASTACE2genetic
27708008
ERFB_YEASTERF2genetic
27708008
RS29A_YEASTRPS29Agenetic
27708008
ATP10_YEASTATP10genetic
27708008
DUS3_YEASTDUS3genetic
27708008
VIP1_YEASTVIP1genetic
27708008
ERG6_YEASTERG6genetic
27708008
USA1_YEASTUSA1genetic
27708008
GAL80_YEASTGAL80genetic
27708008
ATP18_YEASTATP18genetic
27708008
VPS9_YEASTVPS9genetic
27708008
MSC1_YEASTMSC1genetic
27708008
RCO1_YEASTRCO1genetic
27708008
SIP5_YEASTSIP5genetic
27708008
YM30_YEASTYMR155Wgenetic
27708008
IPB2_YEASTPBI2genetic
27708008
MAS5_YEASTYDJ1genetic
27708008
TOM7_YEASTTOM7genetic
27708008
PHO23_YEASTPHO23genetic
27708008
YNO4_YEASTYNL144Cgenetic
27708008
SWM2_YEASTSWM2genetic
27708008
VPS27_YEASTVPS27genetic
27708008
ATP23_YEASTATP23genetic
27708008
TOP1_YEASTTOP1genetic
27708008
YO13A_YEASTYOL013W-Agenetic
27708008
HIR2_YEASTHIR2genetic
27708008
VPS21_YEASTVPS21genetic
27708008
LEO1_YEASTLEO1genetic
27708008
YOR31_YEASTYOR131Cgenetic
27708008
SERC_YEASTSER1genetic
27708008
HUA2_YEASTHUA2genetic
27708008
MBF1_YEASTMBF1genetic
27708008
PDE2_YEASTPDE2genetic
27708008
CSR2_YEASTCSR2genetic
27708008
ROX1_YEASTROX1genetic
27708008
VPS4_YEASTVPS4genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COX10_YEAST

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Related Literatures of Post-Translational Modification

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