ETFA_YEAST - dbPTM
ETFA_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ETFA_YEAST
UniProt AC Q12480
Protein Name Probable electron transfer flavoprotein subunit alpha, mitochondrial
Gene Name AIM45
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 344
Subcellular Localization Mitochondrion matrix.
Protein Description The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) (By similarity)..
Protein Sequence MFKSLAAVLPRASKAKFLQKNYASTLAFIESSKDGSVSRSSLSLLAAAQKLSNPITAVITGSKAEKTAEALKSSYSCSNLEKLVIFEDSKLDTCLPEQLTPLLVKLLKGGDYSHFVVSNSSVGKSVLPRVGALLDVQPVCEVTVIKDPKTFIRPIYAGNIISTIECQAEKKLLIIRASAFPPIAEGSMDSVTIEKRTDIPPCDLNVTWVKTILTKSERPELTSAQNVVTGGRALKDKETFEKLLSPLADVLHAAIGATRASVDNGLCDNSLQIGQTGKVVAPNLYIAIGVSGAVQHLAGMKDSKVIVAINNDPDAPIFNVADYGLQGDLYKIVPELTEKLGKYK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
40PhosphorylationKDGSVSRSSLSLLAA
CCCCCCHHHHHHHHH		28.2929734811
41PhosphorylationDGSVSRSSLSLLAAA
CCCCCHHHHHHHHHH		22.3721440633
66AcetylationITGSKAEKTAEALKS
EECCHHHHHHHHHHH		58.8724489116
73PhosphorylationKTAEALKSSYSCSNL
HHHHHHHHHCCCCCC		35.0422369663
74PhosphorylationTAEALKSSYSCSNLE
HHHHHHHHCCCCCCC		21.3422369663
75PhosphorylationAEALKSSYSCSNLEK
HHHHHHHCCCCCCCE		22.3122369663
76PhosphorylationEALKSSYSCSNLEKL
HHHHHHCCCCCCCEE		17.0222369663
78PhosphorylationLKSSYSCSNLEKLVI
HHHHCCCCCCCEEEE		38.2122369663
89PhosphorylationKLVIFEDSKLDTCLP
EEEEECCCCCCCCCH		28.1128889911
214PhosphorylationTWVKTILTKSERPEL
EEEEEECCCCCCCCC		28.7726447709
215AcetylationWVKTILTKSERPELT
EEEEECCCCCCCCCC		47.0424489116
216PhosphorylationVKTILTKSERPELTS
EEEECCCCCCCCCCC		33.3326447709
245PhosphorylationETFEKLLSPLADVLH
HHHHHHHHHHHHHHH		28.4422369663
339AcetylationIVPELTEKLGKYK--
HHHHHHHHHCCCC--		58.2524489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ETFA_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ETFA_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ETFA_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
FRDA_YEASTYFH1physical
15961414
SDHA_YEASTSDH1genetic
15961414
RV161_YEASTRVS161genetic
20093466
BRE1_YEASTBRE1genetic
20093466
NHP10_YEASTNHP10genetic
20093466
MAF1_YEASTMAF1genetic
20093466
YD249_YEASTYDR249Cgenetic
20093466
RPOM_YEASTRPO41genetic
20093466
WWM1_YEASTWWM1genetic
20093466
VAM7_YEASTVAM7genetic
20093466
MON1_YEASTMON1genetic
20093466
YHK8_YEASTYHK8genetic
20093466
RL17B_YEASTRPL17Bgenetic
20093466
BRE2_YEASTBRE2genetic
20093466
ATP10_YEASTATP10genetic
20093466
VPS9_YEASTVPS9genetic
20093466
YPT7_YEASTYPT7genetic
20093466
RSF1_YEASTRSF1genetic
20093466
MUB1_YEASTMUB1genetic
20093466
SWS2_YEASTSWS2genetic
20093466
COX5A_YEASTCOX5Agenetic
20093466
PET8_YEASTPET8genetic
20093466
CY1_YEASTCYT1genetic
20093466
COX10_YEASTCOX10genetic
20093466
HDA3_YEASTHDA3genetic
20093466
SRS2_YEASTSRS2genetic
21459050
HSP72_YEASTSSA2physical
22940862
ATPA_YEASTATP1physical
22940862
ETFA_YEASTAIM45physical
22940862
RS29B_YEASTRPS29Bgenetic
27708008
PET8_YEASTPET8genetic
27708008
COX5A_YEASTCOX5Agenetic
27708008
IMG2_YEASTIMG2genetic
27708008
NHP10_YEASTNHP10genetic
27708008
GPR1_YEASTGPR1genetic
27708008
BRE1_YEASTBRE1genetic
27708008
TPS2_YEASTTPS2genetic
27708008
PT122_YEASTPET122genetic
27708008
WWM1_YEASTWWM1genetic
27708008
IES1_YEASTIES1genetic
27708008
UBP6_YEASTUBP6genetic
27708008
MON1_YEASTMON1genetic
27708008
QCR9_YEASTQCR9genetic
27708008
URM1_YEASTURM1genetic
27708008
SNX4_YEASTSNX4genetic
27708008
ASF1_YEASTASF1genetic
27708008
RL17B_YEASTRPL17Bgenetic
27708008
VPS24_YEASTVPS24genetic
27708008
BRE2_YEASTBRE2genetic
27708008
COX12_YEASTCOX12genetic
27708008
SIC1_YEASTSIC1genetic
27708008
COA4_YEASTCOA4genetic
27708008
FKS1_YEASTFKS1genetic
27708008
ARPC3_YEASTARC18genetic
27708008
YPT7_YEASTYPT7genetic
27708008
RSF1_YEASTRSF1genetic
27708008
COX7_YEASTCOX7genetic
27708008
SWS2_YEASTSWS2genetic
27708008
BRE5_YEASTBRE5genetic
27708008
HMI1_YEASTHMI1genetic
27708008
BUB3_YEASTBUB3genetic
27708008
CY1_YEASTCYT1genetic
27708008
DIA2_YEASTDIA2genetic
27708008
HDA3_YEASTHDA3genetic
27708008
QCR2_YEASTQCR2genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ETFA_YEAST

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Related Literatures of Post-Translational Modification

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