COX5A_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: COX5A_YEAST
• UniProt AC: P00424
• Protein Name: Cytochrome c oxidase polypeptide 5A, mitochondrial
• Gene Name: COX5A
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 153
• Subcellular Localization: Mitochondrion inner membrane.
• Protein Sequence: MLRNTFTRAGGLSRITSVRFAQTHALSNAAVMDLQSRWENMPSTEQQDIVSKLSERQKLPWAQLTEPEKQAVWYISYGEWGPRRPVLNKGDSSFIAKGVAAGLLFSVGLFAVVRMAGGQDAKTMNKEWQLKSDEYLKSKNANPWGGYSQVQSK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
52	Acetylation	EQQDIVSKLSERQKL HHHHHHHHHHHHCCC	45.17	24489116
92	Phosphorylation	PVLNKGDSSFIAKGV CCCCCCCHHHHHHHH	35.50	27214570
93	Phosphorylation	VLNKGDSSFIAKGVA CCCCCCHHHHHHHHH	25.97	27214570

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of COX5A_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of COX5A_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of COX5A_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
COX4_YEAST	COX4	physical	16554755
YP216_YEAST	YPL216W	physical	16554755
MSS51_YEAST	MSS51	genetic	18541668
COA2_YEAST	COA2	genetic	18541668

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.