| UniProt ID | VAM7_YEAST | |
|---|---|---|
| UniProt AC | P32912 | |
| Protein Name | Vacuolar morphogenesis protein 7 | |
| Gene Name | VAM7 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 316 | |
| Subcellular Localization | Vacuole. | |
| Protein Description | Essential for proper morphogenesis of the vacuole. May exist as structural reinforcement on the surface of the vacuolar membrane and be required for maintenance against rupture by osmotic pressure.. | |
| Protein Sequence | MAANSVGKMSEKLRIKVDDVKINPKYVLYGVSTPNKRLYKRYSEFWKLKTRLERDVGSTIPYDFPEKPGVLDRRWQRRYDDPEMIDERRIGLERFLNELYNDRFDSRWRDTKIAQDFLQLSKPNVSQEKSQQHLETADEVGWDEMIRDIKLDLDKESDGTPSVRGALRARTKLHKLRERLEQDVQKKSLPSTEVTRRAALLRSLLKECDDIGTANIAQDRGRLLGVATSDNSSTTEVQGRTNNDLQQGQMQMVRDQEQELVALHRIIQAQRGLALEMNEELQTQNELLTALEDDVDNTGRRLQIANKKARHFNNSA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MAANSVGKMSEK ---CCCCCCCHHCCC | 27.76 | 30377154 | |
| 10 | Phosphorylation | ANSVGKMSEKLRIKV CCCCCHHCCCCCEEE | 34.76 | 30377154 | |
| 25 | Acetylation | DDVKINPKYVLYGVS ECEEECCCEEEEEEC | 43.43 | 24489116 | |
| 43 | Phosphorylation | KRLYKRYSEFWKLKT HHHHHHHHHHHHHHH | 30.28 | 20377248 | |
| 47 | Acetylation | KRYSEFWKLKTRLER HHHHHHHHHHHHHHC | 45.48 | 24489116 | |
| 67 | Acetylation | IPYDFPEKPGVLDRR CCCCCCCCCCCCCCC | 47.51 | 24489116 | |
| 157 | Phosphorylation | KLDLDKESDGTPSVR CCCCCCCCCCCCCHH | 47.26 | 28889911 | |
| 188 | Phosphorylation | EQDVQKKSLPSTEVT HHHHHHCCCCCHHHH | 53.18 | 26447709 | |
| 191 | Phosphorylation | VQKKSLPSTEVTRRA HHHCCCCCHHHHHHH | 42.36 | 19684113 | |
| 192 | Phosphorylation | QKKSLPSTEVTRRAA HHCCCCCHHHHHHHH | 32.32 | 26447709 | |
| 228 | Phosphorylation | GRLLGVATSDNSSTT CCEEEEECCCCCCCC | 33.92 | 22369663 | |
| 229 | Phosphorylation | RLLGVATSDNSSTTE CEEEEECCCCCCCCE | 25.67 | 22369663 | |
| 232 | Phosphorylation | GVATSDNSSTTEVQG EEECCCCCCCCEEEC | 33.77 | 24909858 | |
| 233 | Phosphorylation | VATSDNSSTTEVQGR EECCCCCCCCEEECC | 45.67 | 24909858 | |
| 234 | Phosphorylation | ATSDNSSTTEVQGRT ECCCCCCCCEEECCC | 27.14 | 23749301 | |
| 235 | Phosphorylation | TSDNSSTTEVQGRTN CCCCCCCCEEECCCC | 35.79 | 22369663 | |
| 307 | Acetylation | RRLQIANKKARHFNN HHHHHHHHHHHHCCC | 38.50 | 25381059 | |
| 315 | Phosphorylation | KARHFNNSA------ HHHHCCCCC------ | 36.14 | 19795423 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VAM7_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VAM7_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VAM7_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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