YIP5_YEAST - dbPTM
YIP5_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID YIP5_YEAST
UniProt AC P53108
Protein Name Protein YIP5
Gene Name YIP5
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 310
Subcellular Localization Membrane
Multi-pass membrane protein .
Protein Description Possible role in vesicle-mediated transport. May be involved in proper membrane localization of Rab GTPases..
Protein Sequence MPSNNSSFLDIDDDLEGVDDFGNEPNPFDDATVPDSPNMNNSTAGKGSEFYNTTGSKAESAPLQGQMDPPAYDQVIGQNDNDGLGRNGLRPGLINYYSKYFQIDLTQFKKRLSAVLTFRNDHNSESNEDNTDLYGAVWITATVVMINFTMSRGLNFIISDVIEGVKTGEDIDRASQFKKLLHSIWLFYGYTFGVPFITMQVLNRDEHSERNRSFKSVPELISVYGYANLIWIPVCVILNILDMSKRLRTVQAIQWAIVALGWAQSSYFLNSQISSNNNTETQSNGKFSLSIIVVVALHTLFCLLFRFIIF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
53PhosphorylationKGSEFYNTTGSKAES
CCCCCCCCCCCCHHC		22.5822369663
54PhosphorylationGSEFYNTTGSKAESA
CCCCCCCCCCCHHCC		35.5022369663
56PhosphorylationEFYNTTGSKAESAPL
CCCCCCCCCHHCCCC		26.9722369663
57UbiquitinationFYNTTGSKAESAPLQ
CCCCCCCCHHCCCCC		58.4823749301
60PhosphorylationTTGSKAESAPLQGQM
CCCCCHHCCCCCCCC		39.7927214570
109AcetylationQIDLTQFKKRLSAVL
EEEHHHHHHHHHHHE		27.4524489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources
-KUbiquitinationE3 ubiquitin ligaseRSP5P39940
PMID:22199232
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of YIP5_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of YIP5_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YIP4_YEASTYIP4physical
10688190
ORM2_YEASTORM2genetic
16269340
GET1_YEASTGET1genetic
16269340
EMP24_YEASTEMP24genetic
16269340
GPI8_YEASTGPI8genetic
16269340
ARV1_YEASTARV1genetic
16269340
CHO2_YEASTCHO2genetic
16269340
SCS7_YEASTSCS7genetic
16269340
LHS1_YEASTLHS1genetic
16269340
PHO86_YEASTPHO86genetic
16269340
TVP23_YEASTTVP23physical
11283351
YIP4_YEASTYIP4physical
11283351
CSG2_YEASTCSG2genetic
23891562
DHAS_YEASTHOM2genetic
27708008
DCOR_YEASTSPE1genetic
27708008
PFKA2_YEASTPFK2genetic
27708008
MET22_YEASTMET22genetic
27708008
TRS23_YEASTTRS23genetic
29674565
VPS35_YEASTVPS35genetic
29674565
RIC1_YEASTRIC1genetic
29674565
YPT6_YEASTYPT6genetic
29674565
FKS1_YEASTFKS1genetic
29674565
RTC6_YEASTRTC6genetic
29674565
SIF2_YEASTSIF2genetic
29674565
RV161_YEASTRVS161genetic
29674565
SCW4_YEASTSCW4genetic
29674565
HSE1_YEASTHSE1genetic
29674565
VPS29_YEASTVPS29genetic
29674565
RPA34_YEASTRPA34genetic
29674565
DOA1_YEASTDOA1genetic
29674565
SA190_YEASTSAP190genetic
29674565
CFT2_YEASTCFT2genetic
29674565
SRN2_YEASTSRN2genetic
29674565
AP1S1_YEASTAPS1genetic
29674565
RNH2A_YEASTRNH201genetic
29674565
AHC1_YEASTAHC1genetic
29674565
VPS5_YEASTVPS5genetic
29674565
TGS1_YEASTTGS1genetic
29674565
H4_YEASTHHF1genetic
29674565
ELO2_YEASTELO2genetic
29674565
VRP1_YEASTVRP1genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of YIP5_YEAST

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Related Literatures of Post-Translational Modification

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