| UniProt ID | SRN2_YEAST | |
|---|---|---|
| UniProt AC | Q99176 | |
| Protein Name | Protein SRN2 | |
| Gene Name | SRN2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 213 | |
| Subcellular Localization |
Cytoplasm . Endosome . Late endosome membrane Peripheral membrane protein . |
|
| Protein Description | Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for normal endocytic and biosynthetic traffic to the yeast vacuole.. | |
| Protein Sequence | MKVKATKLRIKQRRKNKGLNISRLDIIRAEMDVVPSPGLPEKVNEKSKNIPLPEGINLLSSKEIIDLIQTHRHQLELYVTKFNPLTDFAGKIHAFRDQFKQLEENFEDLHEQKDKVQALLENCRILESKYVASWQDYHSEFSKKYGDIALKKKLEQNTKKLDEESSQLETTTRSIDSADDLDQFIKNYLDIRTQYHLRREKLATWDKQGNLKY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 143 | Acetylation | DYHSEFSKKYGDIAL HHHHHHHHHHHHHHH | 56.17 | 24489116 | |
| 144 | Acetylation | YHSEFSKKYGDIALK HHHHHHHHHHHHHHH | 53.95 | 25381059 | |
| 166 | Phosphorylation | KKLDEESSQLETTTR HHHHHHHHHHHHHHH | 41.90 | 27017623 | |
| 171 | Phosphorylation | ESSQLETTTRSIDSA HHHHHHHHHHCCCCH | 15.73 | 27017623 | |
| 172 | Phosphorylation | SSQLETTTRSIDSAD HHHHHHHHHCCCCHH | 29.82 | 27017623 | |
| 177 | Phosphorylation | TTTRSIDSADDLDQF HHHHCCCCHHHHHHH | 31.74 | 27214570 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SRN2_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SRN2_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SRN2_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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