| UniProt ID | HOC1_YEAST | |
|---|---|---|
| UniProt AC | P47124 | |
| Protein Name | Putative glycosyltransferase HOC1 | |
| Gene Name | HOC1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 396 | |
| Subcellular Localization |
Golgi apparatus, cis-Golgi network membrane Single-pass type II membrane protein . |
|
| Protein Description | The M-Pol II complex possesses alpha-1,6-mannosyltransferase activity and is probably involved in the elongation of the mannan backbone of N-linked glycans on cell wall and periplasmic proteins.. | |
| Protein Sequence | MAKTTKRASSFRRLMIFAIIALISLAFGVRYLFHNSNATDLQKILQNLPKEISQSINSANNIQSSDSDLVQHFESLAQEIRHQQEVQAKQFDKQRKILEKKIQDLKQTPPEATLRERIAMTFPYDSHVKFPAFIWQTWSNDEGPERVQDIKGMWESKNPGFAHEVLNHDVINALVHHYFYSIPEILETYEALPSIILKIDFFKYLILLVHGGVYADIDTFPVQPIPNWIPEELSPSDIGLIVGVEEDAQRADWRTKYIRRLQFGTWIIQAKPGHPVLREIISRIIETTLQRKRDDQLNVNLRNDLNIMSWTGSGLWTDTIFTYFNDFMRSGVREKVTWKLFHNLNQPKLLSDVLVFPKFSFNCPNQIDNDDPHKKFYFITHLASQFWKNTPKVEQK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 37 | N-linked_Glycosylation | RYLFHNSNATDLQKI HHHHCCCCHHHHHHH | 52.77 | - | |
| 100 | Acetylation | KQRKILEKKIQDLKQ HHHHHHHHHHHHHHC | 52.29 | 25381059 | |
| 101 | Acetylation | QRKILEKKIQDLKQT HHHHHHHHHHHHHCC | 35.90 | 25381059 | |
| 106 | Ubiquitination | EKKIQDLKQTPPEAT HHHHHHHHCCCCCCC | 61.49 | 23749301 | |
| 121 | Phosphorylation | LRERIAMTFPYDSHV HHHHHCHHCCCCCCC | 16.67 | 27017623 | |
| 124 | Phosphorylation | RIAMTFPYDSHVKFP HHCHHCCCCCCCCCC | 26.36 | 27017623 | |
| 126 | Phosphorylation | AMTFPYDSHVKFPAF CHHCCCCCCCCCCEE | 25.08 | 27017623 | |
| 339 | Acetylation | VREKVTWKLFHNLNQ HHHHHHHHHHCCCCC | 31.73 | 24489116 | |
| 348 | Acetylation | FHNLNQPKLLSDVLV HCCCCCCCCHHHEEE | 52.90 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HOC1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HOC1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HOC1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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