| UniProt ID | DYN3_YEAST | |
|---|---|---|
| UniProt AC | Q04949 | |
| Protein Name | Cytoplasmic dynein intermediate light chain DYN3 | |
| Gene Name | DYN3 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 312 | |
| Subcellular Localization | Cytoplasm, cytoskeleton . Concentrates at motile dots in the cytoplasm corresponding to the plus ends of cytoplasmic microtubules. | |
| Protein Description | Component of the cytoplasmic dynein which acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast. Probably required for normal progression of the cell cycle.. | |
| Protein Sequence | MDNCNAWDKLLSQNESTINSTETATITAIIYSPSSKTLHQFINICFPEGSNSILDTTLINYATIGWTNDLKENYSVDVYTLIRNTDDALDLLKPFLQEHSSKVRWLILLDWTLNDQKLWLNELSYAFNKIKQLNDDNEFSVWCLNSGEILNLQRHTTVWQSVHIDFILQTLRSFCYFNDSSLFYICEDHTEEKREEAQRLKYQELLKHFCEDRDMKDHIEMVKRSEILIPKGCDSIGLIKTVDERFEPTEVKEQHFLARYMDFIPTIDKIREDRKTTSGIDLDKLYPLEVFKVNIQEELGKMFAKYRENSRI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 276 | Phosphorylation | KIREDRKTTSGIDLD HHHCCCCCCCCCCHH | 27.39 | 19779198 | |
| 277 | Phosphorylation | IREDRKTTSGIDLDK HHCCCCCCCCCCHHH | 28.17 | 22369663 | |
| 278 | Phosphorylation | REDRKTTSGIDLDKL HCCCCCCCCCCHHHH | 38.70 | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DYN3_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DYN3_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DYN3_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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