dbPTM

PAC2_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	PAC2_YEAST
UniProt AC	P39937
Protein Name	Protein PAC2
Gene Name	PAC2
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	518
Subcellular Localization	Cytoplasm, cytoskeleton .
Protein Description	Required for viability in the absence of the kinesin-related CIN8 mitotic motor. Seems to be involved in the assembly of alpha-tubulin..
Protein Sequence	MTYEIGDRLKIGGYFCTIKFIGVIKPWPSVKAYGVEWDDHSRGKHSGTIDDIHYFDVQIPNSGSFLKESKIKSPGVRRITFYEALSEKYGGSSNNINDLSIGNKRVEGLGFDELNARNKNYKKLRKIALRDSDVAILFQNQDELNRVIQNCVNVKDLDLSLNLFTNINSLCEFIEPLKNLESLNISQNKLLSGWDNLKEYDLSHIKTLRLSSCGLSYKHIGKLLKSFRTLKMLDLSYNNLTSAGIQNFENEIPCTLEELNISGNNLISFPLFPKNLTLKGLNVSNNQISRAPSIAIYSVESLDITDNKFKERSLIDDLNKTFPSLKNIHLSGNEFNYNGNYINVEEQATFYEVLARFDRVMVLNGSICDVKTRREAEMFFVSKVMNNELSYDTNLPRWSSLIKSYEIDMSKLSFNNERETRQSLVLKIKIRAGKKPSSDLDYWVLPSFTVRYVKSVICRKLNFDILNVKLFHENSEGMINEIKYNFRPISDFNVVNGDIIHVSSPVNNKSIQKVNSPS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
186	Phosphorylation	NLESLNISQNKLLSG CHHHCCCCHHCCCCC	26.99	28152593

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of PAC2_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of PAC2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of PAC2_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RPN1_YEAST	RPN1	physical	11805837
BIK1_YEAST	BIK1	genetic	14764870
TBA3_YEAST	TUB3	genetic	14764870
TBCA_YEAST	RBL2	genetic	14764870
PFD3_YEAST	PAC10	genetic	14764870
BUB1_YEAST	BUB1	genetic	14764870
PFD6_YEAST	YKE2	genetic	14764870
CTF18_YEAST	CTF18	genetic	14764870
PFD4_YEAST	GIM3	genetic	14764870
TBA1_YEAST	TUB1	physical	9725898
CIN1_YEAST	CIN1	physical	10978276
TBCA_YEAST	RBL2	genetic	10978276
CIN1_YEAST	CIN1	genetic	9215891
CIN1_YEAST	CIN1	physical	16554755
CIN8_YEAST	CIN8	genetic	17314980
SWC3_YEAST	SWC3	genetic	17314980
BIK1_YEAST	BIK1	genetic	17314980
VPS72_YEAST	VPS72	genetic	17314980
NUP84_YEAST	NUP84	genetic	17314980
RPN1_YEAST	RPN1	physical	20204449
CDC53_YEAST	CDC53	physical	20204449
MAD1_YEAST	MAD1	genetic	14764870
MAD2_YEAST	MAD2	genetic	14764870
PFD5_YEAST	GIM5	genetic	14764870
SUM1_YEAST	SUM1	genetic	22285862
RPN10_YEAST	RPN10	physical	20204449
TBA1_YEAST	TUB1	physical	20204449
PSA4_YEAST	PRE6	physical	20204449
RPN12_YEAST	RPN12	physical	20204449
DBF4_YEAST	DBF4	genetic	27708008
SAC3_YEAST	SAC3	genetic	27708008
STU1_YEAST	STU1	genetic	27708008
SLI15_YEAST	SLI15	genetic	27708008
SCC1_YEAST	MCD1	genetic	27708008
PRP9_YEAST	PRP9	genetic	27708008
PRP11_YEAST	PRP11	genetic	27708008
TCPD_YEAST	CCT4	genetic	27708008
TCPZ_YEAST	CCT6	genetic	27708008
TCPA_YEAST	TCP1	genetic	27708008
CND3_YEAST	YCG1	genetic	27708008
SYF1_YEAST	SYF1	genetic	27708008
GPI19_YEAST	GPI19	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
SP105_YEAST	SPC105	genetic	27708008
SMD1_YEAST	SMD1	genetic	27708008
DAM1_YEAST	DAM1	genetic	27708008
CTF8_YEAST	CTF8	genetic	27708008
UTP9_YEAST	UTP9	genetic	27708008
MET30_YEAST	MET30	genetic	27708008
TCPE_YEAST	CCT5	genetic	27708008
MAK11_YEAST	MAK11	genetic	27708008
PRP19_YEAST	PRP19	genetic	27708008
STU2_YEAST	STU2	genetic	27708008
RSC9_YEAST	RSC9	genetic	27708008
PDS5_YEAST	PDS5	genetic	27708008
CEF1_YEAST	CEF1	genetic	27708008
NOP2_YEAST	NOP2	genetic	27708008
APC5_YEAST	APC5	genetic	27708008
IPL1_YEAST	IPL1	genetic	27708008
SWC3_YEAST	SWC3	genetic	27708008
SLA1_YEAST	SLA1	genetic	27708008
SWC5_YEAST	SWC5	genetic	27708008
DCC1_YEAST	DCC1	genetic	27708008
BIK1_YEAST	BIK1	genetic	27708008
YCP7_YEAST	YCR007C	genetic	27708008
NUM1_YEAST	NUM1	genetic	27708008
SWR1_YEAST	SWR1	genetic	27708008
VPS72_YEAST	VPS72	genetic	27708008
MAD1_YEAST	MAD1	genetic	27708008
PAN2_YEAST	PAN2	genetic	27708008
PFD3_YEAST	PAC10	genetic	27708008
BUB1_YEAST	BUB1	genetic	27708008
SNF6_YEAST	SNF6	genetic	27708008
EFM1_YEAST	EFM1	genetic	27708008
ARP1_YEAST	ARP1	genetic	27708008
ICE2_YEAST	ICE2	genetic	27708008
MAD2_YEAST	MAD2	genetic	27708008
PHO90_YEAST	PHO90	genetic	27708008
DCOR_YEAST	SPE1	genetic	27708008
DYHC_YEAST	DYN1	genetic	27708008
LDB18_YEAST	LDB18	genetic	27708008
ARP6_YEAST	ARP6	genetic	27708008
VPS71_YEAST	VPS71	genetic	27708008
TBA3_YEAST	TUB3	genetic	27708008
CTF18_YEAST	CTF18	genetic	27708008
JNM1_YEAST	JNM1	genetic	27708008
DYN3_YEAST	DYN3	genetic	27708008
SPO1_YEAST	SPO1	genetic	27708008
MKS1_YEAST	MKS1	genetic	27708008
PFD4_YEAST	GIM3	genetic	27708008
2A5D_YEAST	RTS1	genetic	27708008
BUB3_YEAST	BUB3	genetic	27708008
TBCA_YEAST	RBL2	genetic	27708008
LIS1_YEAST	PAC1	genetic	27708008
KIP2_YEAST	KIP2	genetic	27708008
NIP80_YEAST	NIP100	genetic	27708008
YME1_YEAST	YME1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of PAC2_YEAST

Related Literatures of Post-Translational Modification