PRP9_YEAST - dbPTM
PRP9_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PRP9_YEAST
UniProt AC P19736
Protein Name Pre-mRNA-splicing factor PRP9
Gene Name PRP9
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 530
Subcellular Localization Nucleus.
Protein Description mRNA splicing factors, PRP9, PRP11, and PRP21, are necessary for binding of the U2 snRNP to the pre-mRNA in an early step of spliceosome assembly..
Protein Sequence MNLLETRRSLLEEMEIIENAIAERIQRNPELYYHYIQESSKVFPDTKLPRSSLIAENKIYKFKKVKRKRKQIILQQHEINIFLRDYQEKQQTFNKINRPEETQEDDKDLPNFERKLQQLEKELKNEDENFELDINSKKDKYALFSSSSDPSRRTNILSDRARDLDLNEIFTRDEQYGEYMELEQFHSLWLNVIKRGDCSLLQFLDILELFLDDEKYLLTPPMDRKNDRYMAFLLKLSKYVETFFFKSYALLDAAAVENLIKSDFEHSYCRGSLRSEAKGIYCPFCSRWFKTSSVFESHLVGKIHKKNESKRRNFVYSEYKLHRYLKYLNDEFSRTRSFVERKLAFTANERMAEMDILTQKYEAPAYDSTEKEGAEQVDGEQRDGQLQEEHLSGKSFDMPLGPDGLPMPYWLYKLHGLDREYRCEICSNKVYNGRRTFERHFNEERHIYHLRCLGIEPSSVFKGITKIKEAQELWKNMQGQSQLTSIAAVPPKPNPSQLKVPTELELEEEDEEGNVMSKKVYDELKKQGLV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
145PhosphorylationKDKYALFSSSSDPSR
CCCEEEECCCCCHHH		30.1127017623
146PhosphorylationDKYALFSSSSDPSRR
CCEEEECCCCCHHHH		26.9127017623
158PhosphorylationSRRTNILSDRARDLD
HHHHCHHHHHHHHCC		22.6627017623
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PRP9_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PRP9_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PRP9_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PRP11_YEASTPRP11physical
8969185
PRP21_YEASTPRP21physical
8969185
PRP11_YEASTPRP11physical
8065365
PRP21_YEASTPRP21physical
8065365
PRP21_YEASTPRP21physical
15565172
PRP11_YEASTPRP11physical
15565172
PRP21_YEASTPRP21physical
9207794
SLX5_YEASTSLX5physical
9207794
PT127_YEASTPET127physical
9207794
MDM1_YEASTMDM1physical
9207794
TAF4_YEASTTAF4physical
9207794
MRC1_YEASTMRC1physical
9207794
ARO80_YEASTARO80physical
9207794
VPS72_YEASTVPS72physical
9207794
RSE1_YEASTRSE1physical
9207794
AHC1_YEASTAHC1physical
9207794
ULS1_YEASTULS1physical
9207794
NOP53_YEASTNOP53physical
9207794
PRP11_YEASTPRP11genetic
8211114
PRP21_YEASTPRP21genetic
1505518
PRP21_YEASTPRP21genetic
8602141
NUP59_YEASTASM4genetic
19061648
EFTU_YEASTTUF1genetic
19061648
GBLP_YEASTASC1genetic
19061648
NCBP1_YEASTSTO1genetic
19061648
LSM7_YEASTLSM7genetic
19061648
VAM7_YEASTVAM7genetic
27708008
MAK16_YEASTMAK16genetic
27708008
CDC27_YEASTCDC27genetic
27708008
MED8_YEASTMED8genetic
27708008
NSE3_YEASTNSE3genetic
27708008
RSP5_YEASTRSP5genetic
27708008
MED6_YEASTMED6genetic
27708008
DNA2_YEASTDNA2genetic
27708008
UTP9_YEASTUTP9genetic
27708008
ESS1_YEASTESS1genetic
27708008
NSE1_YEASTNSE1genetic
27708008
SMC4_YEASTSMC4genetic
27708008
NSE5_YEASTNSE5genetic
27708008
ARP9_YEASTARP9genetic
27708008
GPI12_YEASTGPI12genetic
27708008
SMC5_YEASTSMC5genetic
27708008
PSA4_YEASTPRE6genetic
27708008
NUF2_YEASTNUF2genetic
27708008
BRX1_YEASTBRX1genetic
27708008
HRP1_YEASTHRP1genetic
27708008
CH10_YEASTHSP10genetic
27708008
TYSY_YEASTCDC21genetic
27708008
TBF1_YEASTTBF1genetic
27708008
HRR25_YEASTHRR25genetic
27708008
TF2B_YEASTSUA7genetic
27708008
DPM1_YEASTDPM1genetic
27708008
ACE2_YEASTACE2genetic
27708008
RU1A_YEASTMUD1genetic
27708008
RS14A_YEASTRPS14Agenetic
27708008
CEM1_YEASTCEM1genetic
27708008
MSH4_YEASTMSH4genetic
27708008
CWC26_YEASTBUD13genetic
27708008
NAM8_YEASTNAM8genetic
27708008
IST3_YEASTIST3genetic
27708008
LPLA_YEASTAIM22genetic
27708008
FABG_YEASTOAR1genetic
27708008
MUD2_YEASTMUD2genetic
27708008
ARP6_YEASTARP6genetic
27708008
REXO3_YEASTREX3genetic
27708008
ENT2_YEASTENT2genetic
27708008
LIPB_YEASTLIP2genetic
27708008
SEC22_YEASTSEC22genetic
27708008
YNO0_YEASTYNL140Cgenetic
27708008
ATG3_YEASTATG3genetic
27708008
FYV12_YEASTFYV12genetic
27708008
LIPA_YEASTLIP5genetic
27708008
SNU66_YEASTSNU66genetic
27708008
PMT3_YEASTPMT3genetic
27708008
CHL1_YEASTCHL1genetic
27708008
PMA2_YEASTPMA2genetic
27708008
RL21B_YEASTRPL21Bgenetic
27708008
ATG41_YEASTICY2genetic
27708008
BRR1_YEASTBRR1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PRP9_YEAST

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Related Literatures of Post-Translational Modification

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