TF2B_YEAST - dbPTM
TF2B_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TF2B_YEAST
UniProt AC P29055
Protein Name Transcription initiation factor IIB
Gene Name SUA7
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 345
Subcellular Localization Nucleus.
Protein Description General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II..
Protein Sequence MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQTLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGVEKK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
65PhosphorylationDTRSEWRTFSNDDHN
CCHHHHHCCCCCCCC		32.2724930733
67PhosphorylationRSEWRTFSNDDHNGD
HHHHHCCCCCCCCCC		38.4430377154
98UbiquitinationNLSTRIGKGETTDMR
CCCCCCCCCCCCCHH		51.7223749301
121AcetylationQGKNVMDKKDNEVQA
HCCCCCCCCCHHHHH		43.8824489116
170PhosphorylationLKGKSMESIMAASIL
CCCCCHHHHHHHHHH		14.7127017623
205AcetylationVKTKEFGKTLNIMKN
HHHHHHHHHHHHHHH		55.9824489116
211AcetylationGKTLNIMKNILRGKS
HHHHHHHHHHHCCCC		36.7225381059
344AcetylationDNLPGVEKK------
CCCCCCCCC------		62.4724489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TF2B_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TF2B_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TF2B_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
GLT1_YEASTGLT1physical
11805826
IST2_YEASTIST2physical
11805826
EIF3C_YEASTNIP1physical
11805826
EIF3B_YEASTPRT1physical
11805826
EIF3A_YEASTRPG1physical
11805826
EIF3I_YEASTTIF34physical
11805826
EIF3G_YEASTTIF35physical
11805826
IF5_YEASTTIF5physical
11805826
TBP_YEASTSPT15physical
11223526
FCP1_YEASTFCP1physical
11003641
ACE2_YEASTACE2physical
10756191
SSU72_YEASTSSU72physical
10511545
RPB1_YEASTRPO21physical
10464320
TBP_YEASTSPT15physical
8516312
TBP_YEASTSPT15physical
7604282
RPB1_YEASTRPO21physical
14963322
TAF12_YEASTTAF12physical
12297514
SUB1_YEASTSUB1physical
8702984
IMB5_YEASTKAP114physical
15888545
TBP_YEASTSPT15physical
15888545
TBP_YEASTSPT15genetic
12446790
SSU72_YEASTSSU72genetic
10511545
SUB1_YEASTSUB1genetic
10511545
SUB1_YEASTSUB1genetic
8617240
SSU72_YEASTSSU72genetic
8692696
RPB1_YEASTRPO21genetic
8264591
RPB9_YEASTRPB9genetic
8692696
T2FA_YEASTTFG1genetic
15572698
MOT1_YEASTMOT1physical
15861138
RLA1_YEASTRPP1Aphysical
11283351
RM24_YEASTMRPL24physical
11283351
RPB2_YEASTRPB2genetic
15082791
HMO1_YEASTHMO1genetic
18187511
RNA15_YEASTRNA15physical
19602510
T2FA_YEASTTFG1genetic
16147988
RNA14_YEASTRNA14physical
21835917
RNA15_YEASTRNA15physical
21835917
PCF11_YEASTPCF11physical
21835917
HRP1_YEASTHRP1physical
21835917
CLP1_YEASTCLP1physical
21835917
PAP_YEASTPAP1physical
21835917
RAD25_YEASTSSL2genetic
22081613
IMB5_YEASTKAP114physical
22562154
RAD25_YEASTSSL2physical
22751016
MED22_YEASTSRB6genetic
27708008
PRP18_YEASTPRP18genetic
27708008
RU1C_YEASTYHC1genetic
27708008
MED11_YEASTMED11genetic
27708008
RNT1_YEASTRNT1genetic
27708008
FCP1_YEASTFCP1genetic
27708008
SWC3_YEASTSWC3genetic
27708008
AIM4_YEASTAIM4genetic
27708008
PYC2_YEASTPYC2genetic
27708008
SWC5_YEASTSWC5genetic
27708008
CHK1_YEASTCHK1genetic
27708008
VPS41_YEASTVPS41genetic
27708008
H2A1_YEASTHTA1genetic
27708008
SWR1_YEASTSWR1genetic
27708008
VPS72_YEASTVPS72genetic
27708008
UBP3_YEASTUBP3genetic
27708008
BLM10_YEASTBLM10genetic
27708008
RS25A_YEASTRPS25Agenetic
27708008
SNF6_YEASTSNF6genetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
MNN11_YEASTMNN11genetic
27708008
ENT4_YEASTENT4genetic
27708008
ARP6_YEASTARP6genetic
27708008
SEI1_YEASTFLD1genetic
27708008
CDC73_YEASTCDC73genetic
27708008
RL6B_YEASTRPL6Bgenetic
27708008
VPS71_YEASTVPS71genetic
27708008
INO4_YEASTINO4genetic
27708008
MED10_YEASTNUT2physical
27688401
MED14_YEASTRGR1physical
27688401
RPB1_YEASTRPO21genetic
25380729
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TF2B_YEAST

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Related Literatures of Post-Translational Modification

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