| UniProt ID | CWC26_YEAST | |
|---|---|---|
| UniProt AC | P46947 | |
| Protein Name | Pre-mRNA-splicing factor CWC26 | |
| Gene Name | BUD13 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 266 | |
| Subcellular Localization | Cytoplasm. Nucleus. | |
| Protein Description | Required for efficient splicing and pre-mRNA nuclear retention. May also be involved in positioning the proximal bud pole signal.. | |
| Protein Sequence | MALHQYLSETYGPTKPKNKTKKKKKESKSDANSDKTSLIVKERLSTLQQEQEKSGVASFSKFDKQKSKNIWKNLETNELSHAITHPSASSITGNESKNDLKEIRAQEPLVTVADKSKTRKTIYRDAQGHKIQEDSKIDDSSFSRSKYEDEKAAEREQYLKNLNMGDVQKLGINVDAHDKKKNQTASSLTIEDPAITFTHDKERTVKTSLLGRKLYDKPAPENRFAIMPGSRWDGVHRSNGFEEKWFAKQNEINEKKVQSYTLQEDY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 61 | Acetylation | SGVASFSKFDKQKSK HCCCCHHHHHHHHCC | 56.42 | 24489116 | |
| 87 | Phosphorylation | SHAITHPSASSITGN HHHHHCCCHHHCCCC | 32.93 | 21551504 | |
| 90 | Phosphorylation | ITHPSASSITGNESK HHCCCHHHCCCCCCH | 24.72 | 21551504 | |
| 96 | Phosphorylation | SSITGNESKNDLKEI HHCCCCCCHHHHHHH | 40.53 | 21440633 | |
| 135 | Phosphorylation | GHKIQEDSKIDDSSF CCCCCCCCCCCCCCC | 30.66 | 19823750 | |
| 140 | Phosphorylation | EDSKIDDSSFSRSKY CCCCCCCCCCCCHHH | 29.54 | 19823750 | |
| 141 | Phosphorylation | DSKIDDSSFSRSKYE CCCCCCCCCCCHHHH | 33.95 | 23749301 | |
| 143 | Phosphorylation | KIDDSSFSRSKYEDE CCCCCCCCCHHHHHH | 37.28 | 19823750 | |
| 145 | Phosphorylation | DDSSFSRSKYEDEKA CCCCCCCHHHHHHHH | 38.09 | 19823750 | |
| 198 | Phosphorylation | EDPAITFTHDKERTV ECCCEEEECCCCCCE | 22.10 | 21440633 | |
| 201 | Acetylation | AITFTHDKERTVKTS CEEEECCCCCCEEEH | 41.30 | 24489116 | |
| 259 | Phosphorylation | INEKKVQSYTLQEDY CCHHHHHHHCCCCCC | 24.07 | 22369663 | |
| 260 | Phosphorylation | NEKKVQSYTLQEDY- CHHHHHHHCCCCCC- | 8.38 | 22369663 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CWC26_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CWC26_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CWC26_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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