| UniProt ID | KRR1_YEAST | |
|---|---|---|
| UniProt AC | P25586 | |
| Protein Name | KRR1 small subunit processome component | |
| Gene Name | KRR1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 316 | |
| Subcellular Localization | Nucleus, nucleolus . | |
| Protein Description | Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.. | |
| Protein Sequence | MVSTHNRDKPWDTDDIDKWKIEEFKEEDNASGQPFAEESSFMTLFPKYRESYLKTIWNDVTRALDKHNIACVLDLVEGSMTVKTTRKTYDPAIILKARDLIKLLARSVPFPQAVKILQDDMACDVIKIGNFVTNKERFVKRRQRLVGPNGNTLKALELLTKCYILVQGNTVSAMGPFKGLKEVRRVVEDCMKNIHPIYHIKELMIKRELAKRPELANEDWSRFLPMFKKRNVARKKPKKIRNVEKKVYTPFPPAQLPRKVDLEIESGEYFLSKREKQMKKLNEQKEKQMEREIERQEERAKDFIAPEEEAYKPNQN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 9 | Acetylation | VSTHNRDKPWDTDDI CCCCCCCCCCCCCCH | 44.78 | 24489116 | |
| 13 | Phosphorylation | NRDKPWDTDDIDKWK CCCCCCCCCCHHHHC | 31.53 | 19779198 | |
| 18 | Acetylation | WDTDDIDKWKIEEFK CCCCCHHHHCHHHHH | 51.20 | 24489116 | |
| 39 | Phosphorylation | GQPFAEESSFMTLFP CCCCCHHHCHHHHCH | 22.00 | 27017623 | |
| 40 | Phosphorylation | QPFAEESSFMTLFPK CCCCHHHCHHHHCHH | 23.47 | 27017623 | |
| 48 | Phosphorylation | FMTLFPKYRESYLKT HHHHCHHHHHHHHHH | 21.61 | 27017623 | |
| 84 | Phosphorylation | EGSMTVKTTRKTYDP CCCEEEEECCCCCCH | 27.74 | 28889911 | |
| 85 | Phosphorylation | GSMTVKTTRKTYDPA CCEEEEECCCCCCHH | 25.17 | 28889911 | |
| 102 | Acetylation | LKARDLIKLLARSVP HCHHHHHHHHHHCCC | 44.75 | 24489116 | |
| 127 | Acetylation | DMACDVIKIGNFVTN CCCCCEEEECCCCCC | 44.39 | 25381059 | |
| 154 | Acetylation | GPNGNTLKALELLTK CCCCCHHHHHHHHHH | 49.22 | 24489116 | |
| 163 | Phosphorylation | LELLTKCYILVQGNT HHHHHHHEEEEECCE | 9.99 | 19823750 | |
| 170 | Phosphorylation | YILVQGNTVSAMGPF EEEEECCEEECCCCC | 23.74 | 19823750 | |
| 172 | Phosphorylation | LVQGNTVSAMGPFKG EEECCEEECCCCCCC | 15.53 | 19823750 | |
| 246 | Acetylation | KIRNVEKKVYTPFPP HCCCCCCCEECCCCH | 27.28 | 25381059 | |
| 249 | Phosphorylation | NVEKKVYTPFPPAQL CCCCCEECCCCHHHC | 22.80 | 27214570 | |
| 312 | Acetylation | APEEEAYKPNQN--- CCHHHHCCCCCC--- | 44.53 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of KRR1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of KRR1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of KRR1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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