CGR1_YEAST - dbPTM
CGR1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CGR1_YEAST
UniProt AC P53188
Protein Name rRNA-processing protein CGR1
Gene Name CGR1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 120
Subcellular Localization Nucleus, nucleolus .
Protein Description Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit..
Protein Sequence MVNETGESQKAAKGTPVSGKVWKAEKTPLRAKSRVVKNKKLTSWELKKQKRLEDKQFKERLKALKDEKEEARQAKITMLKERREKKEENERYERLAAKMHAKKVERMRRREKRNKALKER
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
13AcetylationGESQKAAKGTPVSGK
CCCCCCCCCCCCCCC
69.0825381059
20AcetylationKGTPVSGKVWKAEKT
CCCCCCCCCCCCCCC
37.1025381059
23AcetylationPVSGKVWKAEKTPLR
CCCCCCCCCCCCCCC
50.0525381059
26AcetylationGKVWKAEKTPLRAKS
CCCCCCCCCCCCCCH
61.3725381059
65AcetylationKERLKALKDEKEEAR
HHHHHHHHHHHHHHH
69.5625381059
68AcetylationLKALKDEKEEARQAK
HHHHHHHHHHHHHHH
71.6224489116
98AcetylationRYERLAAKMHAKKVE
HHHHHHHHHHHHHHH
26.1325381059

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CGR1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CGR1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CGR1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EBP2_YEASTEBP2physical
18467557
RRS1_YEASTRRS1physical
18467557
UPF3_YEASTUPF3genetic
19061648
RRP8_YEASTRRP8genetic
19061648
RS8A_YEASTRPS8Agenetic
19061648
RS8B_YEASTRPS8Agenetic
19061648
IF2A_YEASTSUI2genetic
19061648
LTV1_YEASTLTV1genetic
19061648
FKBP_YEASTFPR1genetic
19061648
YAP6_YEASTYAP6physical
22875988
LOC1_YEASTLOC1physical
25877921
NSA2_YEASTNSA2physical
25877921
EBP2_YEASTEBP2physical
25877921
NOP4_YEASTNOP4physical
25877921
MAK21_YEASTMAK21physical
25877921
RPF2_YEASTRPF2genetic
27811238
NOP4_YEASTNOP4physical
27077951

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CGR1_YEAST

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Related Literatures of Post-Translational Modification

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