LOC1_YEAST - dbPTM
LOC1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID LOC1_YEAST
UniProt AC P43586
Protein Name 60S ribosomal subunit assembly/export protein LOC1
Gene Name LOC1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 204
Subcellular Localization Nucleus, nucleolus .
Protein Description Required for efficient assembly and nuclear export of the 60S ribosomal subunit. Involved in asymmetric localization of ASH1 mRNA..
Protein Sequence MAPKKPSKRQNLRREVAPEVFQDSQARNQLANVPHLTEKSAQRKPSKTKVKKEQSLARLYGAKKDKKGKYSEKDLNIPTLNRAIVPGVKIRRGKKGKKFIADNDTLTLNRLITTIGDKYDDIAESKLEKARRLEEIRELKRKEIERKEALKQDKLEEKKDEIKKKSSVARTIRRKNKRDMLKSEAKASESKTEGRKVKKVSFAQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
24PhosphorylationAPEVFQDSQARNQLA
HHHHHCCHHHHHHHC
18.2423749301
39AcetylationNVPHLTEKSAQRKPS
CCCCCCHHHHCCCCC
45.9524489116
55PhosphorylationTKVKKEQSLARLYGA
CCCHHHHHHHHHHCC
25.7021440633
69AcetylationAKKDKKGKYSEKDLN
CCCCCCCCCCCCCCC
55.2524489116
73AcetylationKKGKYSEKDLNIPTL
CCCCCCCCCCCCCCH
62.6724489116
98AcetylationRRGKKGKKFIADNDT
ECCCCCCCEECCCCC
51.1524489116
118AcetylationLITTIGDKYDDIAES
HHHHHHHHHHHHHHH
45.4224489116
126AcetylationYDDIAESKLEKARRL
HHHHHHHHHHHHHHH
52.7724489116
167PhosphorylationDEIKKKSSVARTIRR
HHHHHHHHHHHHHHH
28.7728889911
171PhosphorylationKKSSVARTIRRKNKR
HHHHHHHHHHHHHHH
14.7528889911
201PhosphorylationGRKVKKVSFAQ----
CCCCCCCEECC----
24.6027717283

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of LOC1_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of LOC1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of LOC1_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
ASH1_YEASTASH1physical
11309412
DBP10_YEASTDBP10physical
16429126
ERB1_YEASTERB1physical
16429126
NOC2_YEASTNOC2physical
16429126
NOC3_YEASTNOC3physical
16429126
NOG1_YEASTNOG1physical
16429126
PESC_YEASTNOP7physical
16429126
NUG1_YEASTNUG1physical
16429126
RLP7_YEASTRLP7physical
16429126
RL16A_YEASTRPL16Aphysical
16429126
RL3_YEASTRPL3physical
16429126
SPB4_YEASTSPB4physical
16429126
IF6_YEASTTIF6physical
16429126
DRS1_YEASTDRS1physical
16429126
MRT4_YEASTMRT4physical
16429126
NIP7_YEASTNIP7physical
16429126
NOP2_YEASTNOP2physical
16429126
RL13B_YEASTRPL13Bphysical
16429126
RL9A_YEASTRPL9Aphysical
16429126
YTM1_YEASTYTM1physical
16429126
BRX1_YEASTBRX1physical
16429126
CIC1_YEASTCIC1physical
16429126
RL30_YEASTRPL30physical
16429126
RL8B_YEASTRPL8Bphysical
16429126
RL31A_YEASTRPL31Aphysical
16429126
SPB1_YEASTSPB1physical
16429126
IPI3_YEASTIPI3physical
16429126
RL25_YEASTRPL25physical
16429126
RL5_YEASTRPL5physical
16429126
RL7A_YEASTRPL7Aphysical
16429126
EBP2_YEASTEBP2physical
16429126
HAS1_YEASTHAS1physical
16429126
NSA1_YEASTNSA1physical
16429126
RL23A_YEASTRPL23Aphysical
16429126
RL23B_YEASTRPL23Aphysical
16429126
RRP5_YEASTRRP5physical
16429126
RPF1_YEASTRPF1physical
16429126
RL4B_YEASTRPL4Bphysical
16429126
RL7B_YEASTRPL7Bphysical
16429126
PUF6_YEASTPUF6genetic
17981122
UBP10_YEASTUBP10physical
18467557
GAR1_YEASTGAR1physical
18467557
EBP2_YEASTEBP2physical
18467557
BRX1_YEASTBRX1physical
18467557
PWP1_YEASTPWP1physical
18467557
NOC2_YEASTNOC2physical
18467557
FKBP4_YEASTFPR4physical
18467557
UBI4P_YEASTUBI4genetic
19061648
EIF3J_YEASTHCR1genetic
19061648
XPOT_YEASTLOS1genetic
19061648
LTV1_YEASTLTV1genetic
19061648
EFTU_YEASTTUF1genetic
19061648
PFD5_YEASTGIM5genetic
19061648
LSM7_YEASTLSM7genetic
19061648
FKBP_YEASTFPR1genetic
19061648
BRR1_YEASTBRR1genetic
19061648
IMB4_YEASTKAP123genetic
19061648
ASH1_YEASTASH1physical
19244342
SHE2_YEASTSHE2physical
19244342
EBP2_YEASTEBP2physical
22319211
ASH1_YEASTASH1physical
25013181
SHE2_YEASTSHE2physical
25013181
PUF6_YEASTPUF6physical
25013181
ASH1_YEASTASH1physical
24324176
LOC1_YEASTLOC1physical
25877921
EBP2_YEASTEBP2physical
25877921
NOP4_YEASTNOP4physical
25877921
NOP53_YEASTNOP53physical
25877921
SKN1_YEASTSKN1genetic
27708008
ATC3_YEASTDRS2genetic
27708008
KC13_YEASTYCK3genetic
27708008
VPS53_YEASTVPS53genetic
27708008
LDB18_YEASTLDB18genetic
27708008
RL38_YEASTRPL38genetic
27708008
YO098_YEASTYOL098Cgenetic
27708008
PUF6_YEASTPUF6genetic
27458021
PUF6_YEASTPUF6physical
27458021
RL8A_YEASTRPL8Aphysical
27458021
RL43A_YEASTRPL43Bphysical
27458021
RL43B_YEASTRPL43Bphysical
27458021
IF6_YEASTTIF6physical
27458021
RL36A_YEASTRPL36Agenetic
29158977
DOM34_YEASTDOM34genetic
29158977

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of LOC1_YEAST

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Related Literatures of Post-Translational Modification

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