| UniProt ID | YTM1_YEAST | |
|---|---|---|
| UniProt AC | Q12024 | |
| Protein Name | Ribosome biogenesis protein YTM1 {ECO:0000255|HAMAP-Rule:MF_03029} | |
| Gene Name | YTM1 {ECO:0000255|HAMAP-Rule:MF_03029, ECO:0000303|Ref.1} | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 460 | |
| Subcellular Localization | Nucleus, nucleolus . Nucleus, nucleoplasm . | |
| Protein Description | Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.. | |
| Protein Sequence | MTEDKSQVKIRFFTREKDELLHVQDTPMYAPISLKRYGLSEIVNHLLGSEKPVPFDFLIEGELLRTSLHDYLTKKGLSSEASLNVEYTRAILPPSYLNSFSNEDWVSSLDVGDGSKHIISGSYDGIVRTWDLSGNVQKQYSGHSGPIRAVKYISNTRLVSAGNDRTLRLWKTKNDDLKLTSQQQAQEDDDDEVNIEDGKTLAILEGHKAPVVSIDVSDNSRILSASYDNSIGFWSTIYKEMTVVDPLEDINNPNNKISTAARKRRKLTMKDGTIRRRAPLSLLESHTAPVEQVIFDSTDNTVGYSVSQDHTIKTWDLVTARCIDTRTTSYSLLSIAQLSTLNLLACGSSARHITLHDPRVGASSKVTQQQLIGHKNFVSSLDTCPENEYILCSGSHDGTVKVWDVRSTSPMYTITREDKSVQKGVNDKVFAVKWAEKVGIISAGQDKKIQINKGDNIFKN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 17 | Acetylation | IRFFTREKDELLHVQ EEEEECCCCEEEEEE | 53.89 | 24489116 | |
| 35 | Acetylation | MYAPISLKRYGLSEI CCCCCCHHHHCHHHH | 36.46 | 24489116 | |
| 166 | Phosphorylation | VSAGNDRTLRLWKTK EECCCCCCEEEEEEC | 21.06 | 19795423 | |
| 172 | Phosphorylation | RTLRLWKTKNDDLKL CCEEEEEECCCCCCC | 24.41 | 19795423 | |
| 180 | Phosphorylation | KNDDLKLTSQQQAQE CCCCCCCCHHHHHHC | 23.93 | 30377154 | |
| 181 | Phosphorylation | NDDLKLTSQQQAQED CCCCCCCHHHHHHCC | 36.11 | 28889911 | |
| 256 | Acetylation | DINNPNNKISTAARK HCCCCCCHHCHHHHH | 44.68 | 24489116 | |
| 340 | Phosphorylation | LSIAQLSTLNLLACG HHHHHHHHHCEECCC | 28.40 | 28889911 | |
| 408 | Phosphorylation | KVWDVRSTSPMYTIT EEEECCCCCCCEEEE | 26.70 | 21440633 | |
| 413 | Phosphorylation | RSTSPMYTITREDKS CCCCCCEEEECCCCH | 15.04 | 27017623 | |
| 419 | Acetylation | YTITREDKSVQKGVN EEEECCCCHHHCCCC | 48.01 | 25381059 | |
| 459 | Acetylation | NKGDNIFKN------ CCCCCCCCC------ | 58.93 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of YTM1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of YTM1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of YTM1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-181 AND THR-340, ANDMASS SPECTROMETRY. | |
