RAD10_YEAST - dbPTM
RAD10_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RAD10_YEAST
UniProt AC P06838
Protein Name DNA repair protein RAD10
Gene Name RAD10
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 210
Subcellular Localization Nucleus.
Protein Description Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Along with RAD1 forms an endonuclease that specifically degrades single-stranded DNA..
Protein Sequence MNNTDPTSFESILAGVAKLRKEKSGADTTGSQSLEIDASKLQQQEPQTSRRINSNQVINAFNQQKPEEWTDSKATDDYNRKRPFRSTRPGKTVLVNTTQKENPLLNHLKSTNWRYVSSTGINMIYYDYLVRGRSVLFLTLTYHKLYVDYISRRMQPLSRNENNILIFIVDDNNSEDTLNDITKLCMFNGFTLLLAFNFEQAAKYIEYLNL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MNNTDPTSFES
----CCCCCCCCHHH
38.0530377154
7Phosphorylation-MNNTDPTSFESILA
-CCCCCCCCHHHHHH
49.1930377154
8PhosphorylationMNNTDPTSFESILAG
CCCCCCCCHHHHHHH
32.1930377154
115PhosphorylationLKSTNWRYVSSTGIN
HHHCCCEEECCCCCC
9.0430377154
117PhosphorylationSTNWRYVSSTGINMI
HCCCEEECCCCCCEE
17.1630377154
118PhosphorylationTNWRYVSSTGINMIY
CCCEEECCCCCCEEE
22.1730377154
119PhosphorylationNWRYVSSTGINMIYY
CCEEECCCCCCEEEE
34.2830377154
125PhosphorylationSTGINMIYYDYLVRG
CCCCCEEEEEEHHCC
4.5930377154
126PhosphorylationTGINMIYYDYLVRGR
CCCCEEEEEEHHCCC
6.2830377154
128PhosphorylationINMIYYDYLVRGRSV
CCEEEEEEHHCCCCC
7.3230377154

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RAD10_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RAD10_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RAD10_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SODM_YEASTSOD2physical
11805837
RAD1_YEASTRAD1physical
11805837
RIR2_YEASTRNR2physical
11805837
PROB_YEASTPRO1physical
11805837
ARC1_YEASTARC1physical
11805837
CYPH_YEASTCPR1physical
11805837
IF4A_YEASTTIF2physical
11805837
VATA_YEASTVMA1physical
11805837
SAHH_YEASTSAH1physical
11805837
FUMH_YEASTFUM1physical
11805837
EI2BG_YEASTGCD1physical
10688190
CSM1_YEASTCSM1physical
10688190
RAD1_YEASTRAD1physical
8621533
RAD1_YEASTRAD1physical
1620114
RAD1_YEASTRAD1physical
1518857
MSH2_YEASTMSH2physical
9826691
RAD14_YEASTRAD14physical
8621533
RAD52_YEASTRAD52genetic
2188090
ATR_YEASTMEC1genetic
15687264
ELG1_YEASTELG1genetic
15687264
RAD5_YEASTRAD5genetic
15687264
RAD18_YEASTRAD18genetic
15687264
MRE11_YEASTMRE11genetic
15687264
RAD52_YEASTRAD52genetic
15687264
RFA1_YEASTRFA1genetic
15687264
FEN1_YEASTRAD27genetic
15687264
MUS81_YEASTMUS81genetic
15687264
RAD1_YEASTRAD1physical
16554755
PIH1_YEASTPIH1genetic
17314980
RAD18_YEASTRAD18genetic
17314980
PRP18_YEASTPRP18genetic
17314980
VRP1_YEASTVRP1genetic
17314980
MFT1_YEASTMFT1genetic
17314980
APN1_YEASTAPN1genetic
17314980
SHG1_YEASTSHG1genetic
17314980
APN1_YEASTAPN1genetic
17535927
APN2_YEASTAPN2genetic
17535927
RAD18_YEASTRAD18genetic
18931302
PFD2_YEASTGIM4genetic
18931302
MMS4_YEASTMMS4genetic
15687264
COG4_YEASTCOG4genetic
21288874
MSH2_YEASTMSH2genetic
9826691
VAM3_YEASTVAM3genetic
27708008
SLX5_YEASTSLX5genetic
27708008
ARO1_YEASTARO1genetic
27708008
APN1_YEASTAPN1genetic
27708008
TOP3_YEASTTOP3genetic
27708008
NST1_YEASTNST1genetic
27708008
RMI1_YEASTRMI1genetic
27708008
HSP7F_YEASTSSE1genetic
27708008
SPEE_YEASTSPE3genetic
27708008
MED1_YEASTMED1genetic
27708008
RAD1_YEASTRAD1physical
29660012
MSH3_YEASTMSH3physical
29660012
MSH2_YEASTMSH2physical
29660012

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RAD10_YEAST

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Related Literatures of Post-Translational Modification

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