| UniProt ID | SPEE_YEAST | |
|---|---|---|
| UniProt AC | Q12074 | |
| Protein Name | Spermidine synthase | |
| Gene Name | SPE3 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 293 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MAQEITHPTIVDGWFREISDTMWPGQAMTLKVEKVLHHEKSKYQDVLIFKSTTYGNVLVLDNVIQATERDEFAYQEMIAHLALNSHPNPKKVLVIGGGDGGVLREVVKHDSVEEAWLCDIDEAVIRLSKEYLPEMAASYSHPKVKTHIGDGFQFLRDYQNTFDVIITDSSDPEGPAETLFQKEYFQLLNSALTEKGVITTQAESMWIHLPIIKDLKKACSEVFPVAEYSFVTIPTYPTGTIGFMVCSKDKTCNVKKPLREISDEKEAELYRYYNKKIHEASFVLPTWAAKELN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 6 | Phosphorylation | --MAQEITHPTIVDG --CCCCCCCCCEECC | 22.50 | 30377154 | |
| 9 | Phosphorylation | AQEITHPTIVDGWFR CCCCCCCCEECCHHH | 26.48 | 30377154 | |
| 19 | Phosphorylation | DGWFREISDTMWPGQ CCHHHHCCCCCCCCC | 23.44 | 30377154 | |
| 21 | Phosphorylation | WFREISDTMWPGQAM HHHHCCCCCCCCCEE | 17.85 | 30377154 | |
| 29 | Phosphorylation | MWPGQAMTLKVEKVL CCCCCEEEEEHHHHH | 26.83 | 30377154 | |
| 31 | Ubiquitination | PGQAMTLKVEKVLHH CCCEEEEEHHHHHHC | 38.90 | 23749301 | |
| 31 | Acetylation | PGQAMTLKVEKVLHH CCCEEEEEHHHHHHC | 38.90 | 24489116 | |
| 34 | Acetylation | AMTLKVEKVLHHEKS EEEEEHHHHHHCCHH | 53.75 | 24489116 | |
| 42 | Ubiquitination | VLHHEKSKYQDVLIF HHHCCHHCCCEEEEE | 58.98 | 24961812 | |
| 42 | Acetylation | VLHHEKSKYQDVLIF HHHCCHHCCCEEEEE | 58.98 | 24489116 | |
| 129 | Acetylation | EAVIRLSKEYLPEMA HHHHHHCHHHHHHHH | 55.78 | 24489116 | |
| 138 | Phosphorylation | YLPEMAASYSHPKVK HHHHHHHHCCCCCCE | 20.03 | 24961812 | |
| 140 | Phosphorylation | PEMAASYSHPKVKTH HHHHHHCCCCCCEEE | 30.71 | 24961812 | |
| 265 | Acetylation | LREISDEKEAELYRY HHHCCCHHHHHHHHH | 68.18 | 24489116 | |
| 265 | Succinylation | LREISDEKEAELYRY HHHCCCHHHHHHHHH | 68.18 | 23954790 | |
| 265 | Ubiquitination | LREISDEKEAELYRY HHHCCCHHHHHHHHH | 68.18 | 23749301 | |
| 265 | 2-Hydroxyisobutyrylation | LREISDEKEAELYRY HHHCCCHHHHHHHHH | 68.18 | - | |
| 275 | Ubiquitination | ELYRYYNKKIHEASF HHHHHHHHHHHHHHC | 36.66 | 22817900 | |
| 276 | Ubiquitination | LYRYYNKKIHEASFV HHHHHHHHHHHHHCC | 45.73 | 23749301 | |
| 290 | Acetylation | VLPTWAAKELN---- CCCHHHHHHCC---- | 55.79 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SPEE_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SPEE_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SPEE_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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