| UniProt ID | GMC1_YEAST | |
|---|---|---|
| UniProt AC | Q04399 | |
| Protein Name | Putative multicopper oxidase GMC1 | |
| Gene Name | GMC1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 608 | |
| Subcellular Localization | ||
| Protein Description | Could be a iron transport multicopper oxidase, which is required for Fe(2+) high affinity uptake. May be required to oxidize Fe(2+) and release it from the transporter. Essential component of copper-dependent iron transport (By similarity). Involved in meiotic prophase and synaptonemal complex (SC) assembly.. | |
| Protein Sequence | MKVILLKPVQLPMLLLILLKFIMAAKEGKIHVLEFNASSEYTLDKRRVISINGYSATFGPEIRVKSGDTLNLKLTNWICSEEEASKDSDVWKDYCSTALHFHGVVPLANEFDGIPGLTQPTIGYGESYWYNFTIDQSTCGTFWYHSHSSVQYGDGMRGVLIVECDDYDNHVANTINSVRDIETLDDGVVTMKKDKHTKELTDYEVQERIITLSDWYTNWNLDILNDKVLSSTGGTDPKFDGSLINGKSSDGETIKIGFNTEYLLLRIVNSGMSGTQVFHLDGFQLIVLEADGIMIKPFIVQTINLAVGQRYTILVKLKSDTSFIRMINGCNKMMGYITKQWWFYKEGAHLDLPKNPNDVSIEHLPGFTKAELYRDIEPTQEENKKLRTKADPVAVFEFDYAYYKDESTKQKYGTGMYKVNERTFSEYVKDPVRFGFNETYDIVINSLDHMRHPWHMHGHHFQIISLGNKGDGPFHKDVQEGKAWSRYQNDLRHLARTGKAPMVRDSINIAGNSYAVLRINTEMPGKWLLHCHVEWHMMKGLGIVFEVPTTTEDSTKQATTAVLSYPTKEPDPNTVVHTAALEQNKSKVIAVYILIMCAVDAIFYWLLM | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 183 | Phosphorylation | NSVRDIETLDDGVVT HCCCCCEECCCCEEE | 28889911 | ||
| 248 | Phosphorylation | GSLINGKSSDGETIK CCEECCCCCCCCEEE | 22890988 | ||
| 249 | Phosphorylation | SLINGKSSDGETIKI CEECCCCCCCCEEEE | 22890988 | ||
| 253 | Phosphorylation | GKSSDGETIKIGFNT CCCCCCCEEEEEEEH | 22890988 | ||
| 260 | Phosphorylation | TIKIGFNTEYLLLRI EEEEEEEHHEEEEEH | 22890988 | ||
| 262 | Phosphorylation | KIGFNTEYLLLRIVN EEEEEHHEEEEEHHH | 22890988 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of GMC1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of GMC1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of GMC1_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SPO11_YEAST | SPO11 | genetic | 22194413 | |
| SLX5_YEAST | SLX5 | genetic | 27708008 | |
| GPR1_YEAST | GPR1 | genetic | 27708008 | |
| MED5_YEAST | NUT1 | genetic | 27708008 | |
| TRS65_YEAST | TRS65 | genetic | 27708008 | |
| TBP7_YEAST | YTA7 | genetic | 27708008 | |
| DAL81_YEAST | DAL81 | genetic | 27708008 | |
| NAA30_YEAST | MAK3 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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