| UniProt ID | TBP7_YEAST | |
|---|---|---|
| UniProt AC | P40340 | |
| Protein Name | Tat-binding homolog 7 | |
| Gene Name | YTA7 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 1379 | |
| Subcellular Localization | ||
| Protein Description | ||
| Protein Sequence | MARNLRNRRGSDVEDASNAKVGYETQIKDENGIIHTTTRSLRKINYAEIEKVFDFLEDDQVMDKDETPVDVTSDEHHNNNQKGDDEDDDVDLVSPHENARTNEELTNERNLRKRKAHDPEEDDESFHEEDVDDDEEEEEADEFEDEYLDEDSKDNNRRRRAADRKFVVPDPDDDEEYDEDDEEGDRISHSASSKRLKRANSRRTRSSRHPETPPPVRRALRSRTRHSRTSNEENDDENDNSRNEALTLADEIRELQEDSPIREKRFLRERTKPVNYKLPPPLTASNAEEFIDKNNNALSFHNPSPARRGRGGWNASQNSGPTRRLFPTGGPFGGNDVTTIFGKNTNFYNQVPSAFSDNNNNKLILDSDSSDDEILPLGVTPKTKKENTQKKKKKKPEIADLDPLGVDMNVNFDDIGGLDNYIDQLKEMVALPLLYPELYQNFNITPPRGVLFHGPPGTGKTLMARALAASCSSDERKITFFMRKGADILSKWVGEAERQLRLLFEEAKKHQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDGMDNRGQVIVIGATNRPDAVDPALRRPGRFDREFYFPLPDVKARFKILQIQTRKWSSPLSTNFIDKLAFLTKGYGGADLRSLCTEAALISIQRSFPQIYRSNDKLLVDPSKIKVKVSDFMLALKKIVPSSARSTGSSPQPLPELIKPLLADQLNNLKNKLDYMLNIKDTTFQRNTSLLQNFIDYEEYSGEEEEHDKYGGNEDTSSFRSYEFFESMAESQICKPRLLINGPKGNGQQYVGAAILNYLEEFNVQNLDLASLVSESSRTIEAAVVQSFMEAKKRQPSVVFIPNLDIWINTIPENVILVLSGLFRSLQSNEKILLLCLAENLDISEVKNGILSDFAFDKNIFQLHKPSKENITRYFSNLIELLKTKPSDIPMKKRRVKPLPELQKVTSNAAPTNFDENGEPLSEKVVLRRKLKSFQHQDMRLKNVLKIKLSGLMDLFKNRYKRFRKPPIDDAFLVHLFEPETSNDPNWQPAYIKDENMILEVSTGRKFFNMDLDIVEERLWNGYYSEPKQFLKDIELIYRDANTIGDRERVIKASEMFANAQMGIEEISTPDFIQECKATRQRDLERQELFLEDEEKRAAMELEAKEQSQENILQEPDLKDNKANEFGVAAGNQLQAQLQTTINTASIVNNSEVPQPIDTNLYKKEIPAAIPSAVDKEKAVIPEDSGANEEYTTELIQATCTSEITTDDDERARKEPKENEDSLQTQVTEENFSKIDANTNNINHVKEIQSVNKPNSLHETVEKRERSPIPKEVVEPEQGKKSDKELILTPEQIKKVSACLIEHCQNFTVSQLEDVHSSVAKIIWKSKSAWDKTGTVDEIIKFLSE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MARNLRNRR ------CCCCCCCCC | 22.00 | 17287358 | |
| 11 | Phosphorylation | NLRNRRGSDVEDASN CCCCCCCCCHHHHHH | 36.35 | 19823750 | |
| 17 | Phosphorylation | GSDVEDASNAKVGYE CCCHHHHHHCCCCCE | 50.03 | 22890988 | |
| 37 | Phosphorylation | ENGIIHTTTRSLRKI CCCEEEECCCHHHCC | 13.17 | 21440633 | |
| 38 | Phosphorylation | NGIIHTTTRSLRKIN CCEEEECCCHHHCCC | 21.29 | 21551504 | |
| 46 | Phosphorylation | RSLRKINYAEIEKVF CHHHCCCHHHHHHHH | 14.75 | 21440633 | |
| 67 | Phosphorylation | QVMDKDETPVDVTSD CCCCCCCCCCCCCCC | 38.45 | 28889911 | |
| 72 | Phosphorylation | DETPVDVTSDEHHNN CCCCCCCCCCCCCCC | 26.46 | 19795423 | |
| 73 | Phosphorylation | ETPVDVTSDEHHNNN CCCCCCCCCCCCCCC | 40.63 | 19795423 | |
| 94 | Phosphorylation | DDDVDLVSPHENART CCCCCCCCCCCCCCC | 28.03 | 22369663 | |
| 106 | Phosphorylation | ARTNEELTNERNLRK CCCCHHHHHHHHHHH | 38.01 | 21440633 | |
| 125 | Phosphorylation | DPEEDDESFHEEDVD CCCCCCCCCCCCCCC | 38.61 | 21551504 | |
| 177 | Phosphorylation | DPDDDEEYDEDDEEG CCCCCCCCCCCCCCC | 23.68 | 19823750 | |
| 188 | Phosphorylation | DEEGDRISHSASSKR CCCCCCCCCCHHHHH | 16.57 | 19823750 | |
| 190 | Phosphorylation | EGDRISHSASSKRLK CCCCCCCCHHHHHHH | 24.05 | 21440633 | |
| 192 | Phosphorylation | DRISHSASSKRLKRA CCCCCCHHHHHHHHH | 39.13 | 21440633 | |
| 193 | Phosphorylation | RISHSASSKRLKRAN CCCCCHHHHHHHHHH | 22.85 | 21440633 | |
| 194 | Acetylation | ISHSASSKRLKRANS CCCCHHHHHHHHHHH | 60.29 | 24489116 | |
| 206 | Phosphorylation | ANSRRTRSSRHPETP HHHCCCHHCCCCCCC | 30.98 | 22369663 | |
| 207 | Phosphorylation | NSRRTRSSRHPETPP HHCCCHHCCCCCCCH | 31.17 | 22369663 | |
| 212 | Phosphorylation | RSSRHPETPPPVRRA HHCCCCCCCHHHHHH | 45.61 | 22369663 | |
| 229 | Phosphorylation | SRTRHSRTSNEENDD HCCCCCCCCCCCCCC | 38.63 | 22369663 | |
| 230 | Phosphorylation | RTRHSRTSNEENDDE CCCCCCCCCCCCCCC | 40.93 | 22369663 | |
| 241 | Phosphorylation | NDDENDNSRNEALTL CCCCCCCHHHHHHHH | 39.07 | 22369663 | |
| 247 | Phosphorylation | NSRNEALTLADEIRE CHHHHHHHHHHHHHH | 27.27 | 21440633 | |
| 259 | Phosphorylation | IRELQEDSPIREKRF HHHHHCCCCHHHHHH | 22.83 | 22369663 | |
| 283 | Phosphorylation | YKLPPPLTASNAEEF CCCCCCCCCCCHHHH | 33.54 | 30377154 | |
| 285 | Phosphorylation | LPPPLTASNAEEFID CCCCCCCCCHHHHHH | 31.19 | 28889911 | |
| 299 | Phosphorylation | DKNNNALSFHNPSPA HCCCCCCCCCCCCCC | 23.27 | 22890988 | |
| 304 | Phosphorylation | ALSFHNPSPARRGRG CCCCCCCCCCCCCCC | 36.19 | 22369663 | |
| 316 | Phosphorylation | GRGGWNASQNSGPTR CCCCCCCCCCCCCCC | 27.04 | 25752575 | |
| 319 | Phosphorylation | GWNASQNSGPTRRLF CCCCCCCCCCCCEEC | 38.21 | 23749301 | |
| 353 | Phosphorylation | NFYNQVPSAFSDNNN CCCCCCCCCCCCCCC | 42.99 | 21440633 | |
| 356 | Phosphorylation | NQVPSAFSDNNNNKL CCCCCCCCCCCCCEE | 38.86 | 21440633 | |
| 367 | Phosphorylation | NNKLILDSDSSDDEI CCEEEECCCCCCCCC | 35.63 | 22890988 | |
| 369 | Phosphorylation | KLILDSDSSDDEILP EEEECCCCCCCCCCC | 39.35 | 22890988 | |
| 370 | Phosphorylation | LILDSDSSDDEILPL EEECCCCCCCCCCCC | 54.81 | 22890988 | |
| 380 | Phosphorylation | EILPLGVTPKTKKEN CCCCCCCCCCCCHHC | 19.78 | 22890988 | |
| 460 | Ubiquitination | HGPPGTGKTLMARAL CCCCCCCHHHHHHHH | 38.02 | 22817900 | |
| 657 | Phosphorylation | DKLLVDPSKIKVKVS CEEEECHHHCEEEHH | 42.42 | 28889911 | |
| 658 | Acetylation | KLLVDPSKIKVKVSD EEEECHHHCEEEHHH | 52.51 | 24489116 | |
| 716 | Phosphorylation | YMLNIKDTTFQRNTS HHHHCCCCCHHHCHH | 25.22 | 19823750 | |
| 717 | Phosphorylation | MLNIKDTTFQRNTSL HHHCCCCCHHHCHHH | 28.09 | 19823750 | |
| 722 | Phosphorylation | DTTFQRNTSLLQNFI CCCHHHCHHHHHHHC | 23.96 | 19823750 | |
| 723 | Phosphorylation | TTFQRNTSLLQNFID CCHHHCHHHHHHHCC | 30.54 | 19823750 | |
| 731 | Phosphorylation | LLQNFIDYEEYSGEE HHHHHCCHHHHCCCC | 13.07 | 22369663 | |
| 734 | Phosphorylation | NFIDYEEYSGEEEEH HHCCHHHHCCCCCCC | 15.27 | 20377248 | |
| 735 | Phosphorylation | FIDYEEYSGEEEEHD HCCHHHHCCCCCCCC | 42.90 | 22369663 | |
| 744 | Phosphorylation | EEEEHDKYGGNEDTS CCCCCCCCCCCCCCC | 36.00 | 19779198 | |
| 752 | Phosphorylation | GGNEDTSSFRSYEFF CCCCCCCHHHHHHHH | 27.11 | 22369663 | |
| 859 | Phosphorylation | VLSGLFRSLQSNEKI HHHHHHHHHCCCHHH | 24.35 | 28889911 | |
| 862 | Phosphorylation | GLFRSLQSNEKILLL HHHHHHCCCHHHHHH | 52.85 | 28889911 | |
| 902 | Ubiquitination | FQLHKPSKENITRYF HHCCCCCHHHHHHHH | 64.41 | 24961812 | |
| 940 | Phosphorylation | LPELQKVTSNAAPTN CHHHHHHHCCCCCCC | 24.25 | 23749301 | |
| 941 | Phosphorylation | PELQKVTSNAAPTNF HHHHHHHCCCCCCCC | 27.71 | 25752575 | |
| 946 | Phosphorylation | VTSNAAPTNFDENGE HHCCCCCCCCCCCCC | 43.73 | 24961812 | |
| 967 | Phosphorylation | VLRRKLKSFQHQDMR HHHHHHHHHHCHHHH | 40.34 | 30377154 | |
| 1016 | Phosphorylation | HLFEPETSNDPNWQP ECCCCCCCCCCCCCC | 37.26 | 28889911 | |
| 1062 | Acetylation | NGYYSEPKQFLKDIE CCCCCCHHHHHHHHH | 50.02 | 24489116 | |
| 1086 | Ubiquitination | GDRERVIKASEMFAN CCHHHHHHHHHHHHH | 42.90 | 19722269 | |
| 1142 | Phosphorylation | ELEAKEQSQENILQE HHHHHHHHHHHHHCC | 40.32 | 22369663 | |
| 1206 | Phosphorylation | EIPAAIPSAVDKEKA CCCCCCCCCCCHHHC | 34.51 | 25752575 | |
| 1210 | Acetylation | AIPSAVDKEKAVIPE CCCCCCCHHHCCCCC | 55.29 | 22865919 | |
| 1226 | Phosphorylation | SGANEEYTTELIQAT CCCCHHHHHHHHHHH | 19.64 | 19779198 | |
| 1227 | Phosphorylation | GANEEYTTELIQATC CCCHHHHHHHHHHHH | 28.08 | 19779198 | |
| 1233 | Phosphorylation | TTELIQATCTSEITT HHHHHHHHHHCCCCC | 10.43 | 19779198 | |
| 1236 | Phosphorylation | LIQATCTSEITTDDD HHHHHHHCCCCCCCH | 29.19 | 21551504 | |
| 1239 | Phosphorylation | ATCTSEITTDDDERA HHHHCCCCCCCHHHH | 21.81 | 21551504 | |
| 1240 | Phosphorylation | TCTSEITTDDDERAR HHHCCCCCCCHHHHH | 42.99 | 21551504 | |
| 1256 | Phosphorylation | EPKENEDSLQTQVTE CCCCCHHHHHHHHHH | 19.05 | 21551504 | |
| 1259 | Phosphorylation | ENEDSLQTQVTEENF CCHHHHHHHHHHHHH | 30.24 | 28889911 | |
| 1262 | Phosphorylation | DSLQTQVTEENFSKI HHHHHHHHHHHHHHC | 27.97 | 28889911 | |
| 1267 | Phosphorylation | QVTEENFSKIDANTN HHHHHHHHHCCCCCC | 40.04 | 30377154 | |
| 1284 | Phosphorylation | NHVKEIQSVNKPNSL CCHHHHHHCCCCCCH | 33.06 | 30377154 | |
| 1290 | Phosphorylation | QSVNKPNSLHETVEK HHCCCCCCHHHHHHH | 39.36 | 21551504 | |
| 1294 | Phosphorylation | KPNSLHETVEKRERS CCCCHHHHHHHHCCC | 24.18 | 21440633 | |
| 1301 | Phosphorylation | TVEKRERSPIPKEVV HHHHHCCCCCCHHHC | 23.56 | 21440633 | |
| 1316 | Phosphorylation | EPEQGKKSDKELILT CCCCCCCCCCCCCCC | 58.35 | 19779198 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TBP7_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TBP7_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TBP7_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11; THR-212; SER-241;SER-259; SER-285; SER-304; SER-316; SER-941; SER-1142; SER-1256 ANDTHR-1259, AND MASS SPECTROMETRY. | |
| "Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases."; Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.; Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11; THR-212; SER-241;SER-259 AND SER-1142, AND MASS SPECTROMETRY. | |
| "Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry."; Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.; Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-11 AND SER-17, AND MASSSPECTROMETRY. | |
| "Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-94 AND SER-259, AND MASSSPECTROMETRY. | |
