| UniProt ID | CSK2C_YEAST | |
|---|---|---|
| UniProt AC | P38930 | |
| Protein Name | Casein kinase II subunit beta' | |
| Gene Name | CKB2 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 258 | |
| Subcellular Localization | ||
| Protein Description | Plays a complex role in regulating the basal catalytic activity of the alpha subunit.. | |
| Protein Sequence | MGSRSENVGTVTREGSRVEQDDVLMDDDSDSSEYVDMWIDLFLGRKGHEYFCDVDPEYITDRFNLMNLQKTVSKFSYVVQYIVDDLDDSILENMTHARLEQLESDSRKLYGLIHARYIITIKGLQKMYAKYKEADFGRCPRVYCNLQQLLPVGLHDIPGIDCVKLYCPSCEDLYIPKSSRHSSIDGAYFGTSFPGMFLQAFPDMVPKHPTKRYVPKIFGFELHKQAQLTRWQELQRLKLVEKLESKDVDLTKSGGFKT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MGSRSENVGT -----CCCCCCCCCC | 31.19 | 22369663 | |
| 5 | Phosphorylation | ---MGSRSENVGTVT ---CCCCCCCCCCCC | 34.91 | 22369663 | |
| 10 | Phosphorylation | SRSENVGTVTREGSR CCCCCCCCCCCCCCC | 17.89 | 22369663 | |
| 12 | Phosphorylation | SENVGTVTREGSRVE CCCCCCCCCCCCCCE | 23.88 | 22369663 | |
| 108 | Ubiquitination | QLESDSRKLYGLIHA HHHHHHHHHHHHHHH | 50.44 | 23749301 | |
| 122 | Acetylation | ARYIITIKGLQKMYA HHHHEEEHHHHHHHH | 44.94 | 24489116 | |
| 130 | Ubiquitination | GLQKMYAKYKEADFG HHHHHHHHHHHCCCC | 39.09 | 22817900 | |
| 132 | Ubiquitination | QKMYAKYKEADFGRC HHHHHHHHHCCCCCC | 45.80 | 23749301 | |
| 169 | Phosphorylation | CVKLYCPSCEDLYIP EEEEECCCCHHEECC | 26.95 | 27214570 | |
| 177 | Ubiquitination | CEDLYIPKSSRHSSI CHHEECCCCCCCCCC | 52.05 | 23749301 | |
| 216 | Acetylation | PTKRYVPKIFGFELH CCCCCCCCCCCCCHH | 40.39 | 24489116 | |
| 246 | Acetylation | LVEKLESKDVDLTKS HHHHHHHCCCCCCCC | 53.01 | 24489116 | |
| 257 | Acetylation | LTKSGGFKT------ CCCCCCCCC------ | 57.51 | 25381059 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CSK2C_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CSK2C_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CSK2C_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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