EF1G1_YEAST - dbPTM
EF1G1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID EF1G1_YEAST
UniProt AC P29547
Protein Name Elongation factor 1-gamma 1
Gene Name CAM1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 415
Subcellular Localization Cytoplasm. Nucleus.
Protein Description Subunit of the eukaryotic elongation factor 1 complex (eEF1). Probably plays a role in anchoring the complex to other cellular components. May be involved in transcriptional regulation of MXR1..
Protein Sequence MSQGTLYANFRIRTWVPRGLVKALKLDVKVVTPDAAAEQFARDFPLKKVPAFVGPKGYKLTEAMAINYYLVKLSQDDKMKTQLLGADDDLNAQAQIIRWQSLANSDLCIQIANTIVPLKGGAPYNKKSVDSAMDAVDKIVDIFENRLKNYTYLATENISLADLVAASIFTRYFESLFGTEWRAQHPAIVRWFNTVRASPFLKDEYKDFKFADKPLSPPQKKKEKKAPAAAPAASKKKEEAKPAATETETSSKKPKHPLELLGKSTFVLDDWKRKYSNEDTRPVALPWFWEHYNPEEYSLWKVTYKYNDELTLTFMSNNLVGGFFNRLSASTKYMFGCLVVYGENNNNGIVGAVMVRGQDYVPAFDVAPDWESYDYAKLDPTNDDDKEFINNMWAWDKPVSVNGEPKEIVDGKVLK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Acetylation------MSQGTLYAN
------CCCCCEEEE		37.0022814378
222-HydroxyisobutyrylationWVPRGLVKALKLDVK
ECCHHHHHHHCCEEE		53.71-
29AcetylationKALKLDVKVVTPDAA
HHHCCEEEEECCHHH		30.5624489116
32PhosphorylationKLDVKVVTPDAAAEQ
CCEEEEECCHHHHHH		20.5925752575
56AcetylationVPAFVGPKGYKLTEA
CCCCCCCCCCCHHHH		69.7824489116
782-HydroxyisobutyrylationVKLSQDDKMKTQLLG
EECCCCCHHHHHHCC		51.06-
802-HydroxyisobutyrylationLSQDDKMKTQLLGAD
CCCCCHHHHHHCCCC		38.57-
80UbiquitinationLSQDDKMKTQLLGAD
CCCCCHHHHHHCCCC		38.5724961812
127AcetylationGGAPYNKKSVDSAMD
CCCCCCCCCHHHHHH		52.6624489116
202SuccinylationVRASPFLKDEYKDFK
HCCCCCCCHHHCCCC		49.2223954790
202AcetylationVRASPFLKDEYKDFK
HCCCCCCCHHHCCCC		49.2224489116
206AcetylationPFLKDEYKDFKFADK
CCCCHHHCCCCCCCC		55.4224489116
209UbiquitinationKDEYKDFKFADKPLS
CHHHCCCCCCCCCCC		50.1824961812
213AcetylationKDFKFADKPLSPPQK
CCCCCCCCCCCCCHH		44.4124489116
216PhosphorylationKFADKPLSPPQKKKE
CCCCCCCCCCHHHHH		42.9621440633
234PhosphorylationPAAAPAASKKKEEAK
CCCCCHHHHCHHHCC		47.3028889911
247PhosphorylationAKPAATETETSSKKP
CCCCCCCCCCCCCCC		39.9627717283
249PhosphorylationPAATETETSSKKPKH
CCCCCCCCCCCCCCC		45.8028889911
250PhosphorylationAATETETSSKKPKHP
CCCCCCCCCCCCCCH		33.6528889911
251PhosphorylationATETETSSKKPKHPL
CCCCCCCCCCCCCHH		52.7127717283
263UbiquitinationHPLELLGKSTFVLDD
CHHHHCCCCEEEECC		46.4117644757
264PhosphorylationPLELLGKSTFVLDDW
HHHHCCCCEEEECCH		25.8622369663
265PhosphorylationLELLGKSTFVLDDWK
HHHCCCCEEEECCHH		22.6522369663
272AcetylationTFVLDDWKRKYSNED
EEEECCHHHHCCCCC		46.1124489116
272UbiquitinationTFVLDDWKRKYSNED
EEEECCHHHHCCCCC		46.1117644757
2722-HydroxyisobutyrylationTFVLDDWKRKYSNED
EEEECCHHHHCCCCC		46.11-
272SuccinylationTFVLDDWKRKYSNED
EEEECCHHHHCCCCC		46.1123954790
274UbiquitinationVLDDWKRKYSNEDTR
EECCHHHHCCCCCCC		49.6717644757
276PhosphorylationDDWKRKYSNEDTRPV
CCHHHHCCCCCCCCC		36.4624961812
280PhosphorylationRKYSNEDTRPVALPW
HHCCCCCCCCCCCCC		30.6024961812
397AcetylationNNMWAWDKPVSVNGE
HHHCCCCCCCEECCC		36.3024489116
400PhosphorylationWAWDKPVSVNGEPKE
CCCCCCCEECCCCCE		20.5622369663
412UbiquitinationPKEIVDGKVLK----
CCEECCCEECC----		39.6723749301
412AcetylationPKEIVDGKVLK----
CCEECCCEECC----		39.6724489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of EF1G1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of EF1G1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of EF1G1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
EF1B_YEASTEFB1physical
16429126
HSL1_YEASTHSL1physical
16429126
RAD34_YEASTRAD34physical
16429126
SWD3_YEASTSWD3genetic
19061648
MEX67_YEASTMEX67genetic
19061648
ELP3_YEASTELP3genetic
19061648
CBP2_YEASTCBP2genetic
19061648
RSA3_YEASTRSA3genetic
19061648
MRT4_YEASTMRT4genetic
19061648
RU2A_YEASTLEA1genetic
19061648
PRP4_YEASTPRP4genetic
19061648
SSB1_YEASTSSB1physical
19536198
ELP3_YEASTELP3genetic
19547744
PRP4_YEASTPRP4genetic
19547744
ODP2_YEASTLAT1genetic
27708008
SWS2_YEASTSWS2genetic
27708008
CTU2_YEASTNCS2genetic
27708008
ERV15_YEASTERV15genetic
27708008
STE50_YEASTSTE50genetic
27708008
NAA38_YEASTMAK31genetic
27708008
PEX19_YEASTPEX19genetic
27708008
RAD4_YEASTRAD4genetic
27708008
PALF_YEASTRIM8genetic
27708008
MRM2_YEASTMRM2genetic
27708008
PFD3_YEASTPAC10genetic
27708008
YG37_YEASTYGR127Wgenetic
27708008
TDA11_YEASTTDA11genetic
27708008
POG1_YEASTPOG1genetic
27708008
ATG32_YEASTATG32genetic
27708008
RL17B_YEASTRPL17Bgenetic
27708008
DID2_YEASTDID2genetic
27708008
RFU1_YEASTRFU1genetic
27708008
RAD14_YEASTRAD14genetic
27708008
SCS7_YEASTSCS7genetic
27708008
JNM1_YEASTJNM1genetic
27708008
PET8_YEASTPET8genetic
27708008
COG6_YEASTCOG6genetic
27708008
COX5A_YEASTCOX5Agenetic
27708008
MAS5_YEASTYDJ1genetic
27708008
VPS27_YEASTVPS27genetic
27708008
IZH2_YEASTIZH2genetic
27708008
DOM34_YEASTDOM34genetic
29158977
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of EF1G1_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-32, AND MASSSPECTROMETRY.

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