| UniProt ID | MEX67_YEAST | |
|---|---|---|
| UniProt AC | Q99257 | |
| Protein Name | mRNA export factor MEX67 | |
| Gene Name | MEX67 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 599 | |
| Subcellular Localization | Nucleus. Cytoplasm. Localizes at both the nuclear and cytoplasmic site of the pores. Shuttles between the nucleus and the cytoplasm. | |
| Protein Description | Involved in the export of mRNA from the nucleus to the cytoplasm.. | |
| Protein Sequence | MSGFHNVGNINMMAQQQMQQNRIKISVRNWQNATMNDLINFISRNARVAVYDAHVEGPLVIGYVNSKAEAESLMKWNGVRFAGSNLKFELLDNNGASAGTSDTISFLRGVLLKRYDPQTKLLNLGALHSDPELIQKGVFSSISTQSKMFPAMMKLASTEKSLIVESVNLADNQLKDISAISTLAQTFPNLKNLCLANNQIFRFRSLEVWKNKFKDLRELLMTNNPITTDKLYRTEMLRLFPKLVVLDNVIVRDEQKLQTVYSLPMKIQQFFFENDALGQSSTDFATNFLNLWDNNREQLLNLYSPQSQFSVSVDSTIPPSTVTDSDQTPAFGYYMSSSRNISKVSSEKSIQQRLSIGQESINSIFKTLPKTKHHLQEQPNEYSMETISYPQINGFVITLHGFFEETGKPELESNKKTGKNNYQKNRRYNHGYNSTSNNKLSKKSFDRTWVIVPMNNSVIIASDLLTVRAYSTGAWKTASIAIAQPPQQQASVLPQVASMNPNITTPPQPQPSVVPGGMSIPGAPQGAMVMAPTLQLPPDVQSRLNPVQLELLNKLHLETKLNAEYTFMLAEQSNWNYEVAIKGFQSSMNGIPREAFVQF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Acetylation | ------MSGFHNVGN ------CCCCCCHHH | 50.60 | 22814378 | |
| 129 | Phosphorylation | LNLGALHSDPELIQK ECCCCCCCCHHHHHC | 56.56 | 21440633 | |
| 230 | Acetylation | NNPITTDKLYRTEML CCCCCCCHHHHHHHH | 45.38 | 24489116 | |
| 261 | Phosphorylation | EQKLQTVYSLPMKIQ HHHHHHHHHCCCCHH | 14.10 | 21126336 | |
| 419 | Acetylation | ESNKKTGKNNYQKNR HHCCCCCCCHHHHCC | 47.45 | 25381059 | |
| 424 | Acetylation | TGKNNYQKNRRYNHG CCCCHHHHCCCCCCC | 41.90 | 25381059 | |
| 436 | Phosphorylation | NHGYNSTSNNKLSKK CCCCCCCCCCCCCCC | 37.92 | 25521595 | |
| 448 | Phosphorylation | SKKSFDRTWVIVPMN CCCCCCCEEEEEECC | 26.40 | 29688323 | |
| 457 | Phosphorylation | VIVPMNNSVIIASDL EEEECCCEEEEEECC | 15.08 | 29688323 | |
| 462 | Phosphorylation | NNSVIIASDLLTVRA CCEEEEEECCEEEEE | 20.55 | 29688323 | |
| 466 | Phosphorylation | IIASDLLTVRAYSTG EEEECCEEEEECCCC | 18.42 | 29688323 | |
| 471 | Phosphorylation | LLTVRAYSTGAWKTA CEEEEECCCCCCEEE | 21.27 | 28889911 | |
| 512 | Phosphorylation | TPPQPQPSVVPGGMS CCCCCCCCCCCCCCC | 30.42 | 28889911 | |
| 533 | Phosphorylation | GAMVMAPTLQLPPDV CCEEECCCCCCCCCH | 20.00 | 28889911 | |
| 542 | Phosphorylation | QLPPDVQSRLNPVQL CCCCCHHHCCCHHHH | 38.29 | 28889911 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MEX67_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MEX67_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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