MIP6_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: MIP6_YEAST
• UniProt AC: P38760
• Protein Name: RNA-binding protein MIP6
• Gene Name: MIP6
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 659
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MPNSHGNVLNNISLNSKQNPRSISKSCPNDKDARQKSFKTISAQALVRVQGAGYKLGDVKLKDAEVKEKNSLKKYDCKNATQEKKEQEQVFEKTVAKGSVQKYITKTSKTNSLFIGNLKSTVTEEMLRKIFKRYQSFESAKVCRDFLTKKSLGYGYLNFKDKNDAESARKEFNYTVFFGQEVKIMPSMKNTLFRKNIGTNVFFSNLPLENPQLTTRSFYLIMIEYGNVLSCLLERRKNIGFVYFDNDISARNVIKKYNNQEFFGNKIICGLHFDKEVRTRPEFTKRKKMIGSDIVIEDELLASNNLSDNARSKTILVKNLPSDTTQEEVLDYFSTIGPIKSVFISEKQANTPHKAFVTYKNEEESKKAQKCLNKTIFKNHTIWVGPGKDKPVHNQIGTNKKTKVYLKNLSFNCNKEFISQLCLQEKIRFSEIKITNYNSLNWTFCGHVECFSRSDAERLFNILDRRLIGSSLVEASWSKNNDNILNEIDYDDGNNNENYKKLINISSMMRFRTQELSAHQKGLTSQFQQVVSPFSSYSNSYTNMNSLVATPMKPHPAFNLITNTVDEKLHQPKRTKQENAEILESLKKIINRNLQRISISGLNKEENLRSISEFIFDVFWEHDSERLSHFLLMTNTSLESQKILQKQVTRAAESLGFTV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
4	Phosphorylation	----MPNSHGNVLNN ----CCCCCCCCCCC	27.22	27214570
39	Acetylation	DARQKSFKTISAQAL HHHHHHHHHHCHHHH	52.63	25381059
42	Phosphorylation	QKSFKTISAQALVRV HHHHHHHCHHHHHHH	21.40	27214570
54	Phosphorylation	VRVQGAGYKLGDVKL HHHCCCCCEECCCCC	11.51	27017623
55	Acetylation	RVQGAGYKLGDVKLK HHCCCCCEECCCCCC	45.11	25381059
78	Acetylation	SLKKYDCKNATQEKK CCCCCCCCCCCHHHH	46.87	25381059
175	Phosphorylation	ARKEFNYTVFFGQEV HHHHHCEEEEECCEE	16.37	30377154
187	Phosphorylation	QEVKIMPSMKNTLFR CEEEECHHHCCHHHH	25.63	28889911
312	Phosphorylation	NLSDNARSKTILVKN CCCCCCCCCEEEEEC	31.57	27017623
314	Phosphorylation	SDNARSKTILVKNLP CCCCCCCEEEEECCC	22.31	27017623
360	Acetylation	HKAFVTYKNEEESKK CCEEEEECCHHHHHH	48.82	25381059
506	Phosphorylation	YKKLINISSMMRFRT HHHHHHHHHHHHHHH	14.00	28889911
517	Phosphorylation	RFRTQELSAHQKGLT HHHHHHHHHHHCCHH	23.97	30377154
585	Phosphorylation	ENAEILESLKKIINR HHHHHHHHHHHHHHH	41.88	25005228

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of MIP6_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of MIP6_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of MIP6_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
LCP5_YEAST	LCP5	genetic	19061648
CAK1_YEAST	CAK1	genetic	19061648
PRP19_YEAST	PRP19	genetic	19061648

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.