FOLC_YEAST - dbPTM
FOLC_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID FOLC_YEAST
UniProt AC P36001
Protein Name Probable folylpolyglutamate synthase
Gene Name RMA1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 430
Subcellular Localization Mitochondrion .
Protein Description Conversion of folates to polyglutamate derivatives..
Protein Sequence MDDISGRQTLPRINRLLEHVGNPQDSLSILHIAGTNGKETVSKFLTSILQHPGQQRQRVLIGRYTTSSLLNAKEEDISINNEAISLIEYSRIEKELIEADSSLKLQCNNLELLTSVALVYFAKKNCQWCIIETGLAGKQDPGSIIAGQSRVCCAITNVGISDEAFLCKFLSQITESSTNKAIFLLDGSNDEFVRNTITKRCHDVGCPLEITDPSLRDYNVHTDTWGTLEVRLPYSEEEYQIFNLRVAIAVLDFLSKEKKVCISKDQLSQGLISVDWPRSLHRLDYCYESTSGKKIALLLDNANNAKAARNLACHLRTTYGDTPLTFVIAITTGKKVSPLLDPLIRPQDYVIVTRFGSVVGMPWIQSLEPVNLLAFIKNRYTRNVNMQPDLQSVWTFLETSGLKTIVPVIVCGSLYICKELLRLHNCHLPV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
149PhosphorylationGSIIAGQSRVCCAIT
CCEEECCCEEEEEEE		26.2624909858
392PhosphorylationNMQPDLQSVWTFLET
CCCCCHHHHHHHHHH		27.2429688323
395PhosphorylationPDLQSVWTFLETSGL
CCHHHHHHHHHHCCC		19.0429688323
399PhosphorylationSVWTFLETSGLKTIV
HHHHHHHHCCCCCHH		30.1829688323
400PhosphorylationVWTFLETSGLKTIVP
HHHHHHHCCCCCHHE		32.5229688323
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of FOLC_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of FOLC_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of FOLC_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YP022_YEASTYPR022Cphysical
18719252
ERV15_YEASTERV15genetic
20093466
YGY5_YEASTYGL235Wgenetic
20093466
MET28_YEASTMET28genetic
20093466
MRX5_YEASTYJL147Cgenetic
20093466
YJ24_YEASTKCH1genetic
20093466
COX12_YEASTCOX12genetic
20093466
COA4_YEASTCOA4genetic
20093466
HST1_YEASTHST1genetic
20093466
ASE1_YEASTASE1genetic
20093466
TPO4_YEASTTPO4genetic
20093466
MNE1_YEASTMNE1genetic
20093466
MMT2_YEASTMMT2genetic
20093466
NCBP2_YEASTCBC2genetic
20093466
AIM44_YEASTAIM44genetic
20093466
H1_YEASTHHO1genetic
20093466
HSP7F_YEASTSSE1genetic
20093466
EAF3_YEASTEAF3genetic
20093466
AXL1_YEASTAXL1genetic
20093466
QCR2_YEASTQCR2genetic
20093466
THDH_YEASTILV1genetic
21623372
PUR4_YEASTADE6genetic
21623372
QCR7_YEASTQCR7genetic
21623372
CACP_YEASTCAT2genetic
21623372
ATPA_YEASTATP1genetic
21623372
THI22_YEASTTHI22genetic
21623372
F26_YEASTFBP26genetic
21623372
BNA3_YEASTBNA3genetic
21623372
SKN1_YEASTSKN1genetic
21623372
ARO1_YEASTARO1genetic
21623372
FCY1_YEASTFCY1genetic
21623372
CEM1_YEASTCEM1genetic
21623372
YPC1_YEASTYPC1genetic
21623372
CSG2_YEASTCSG2genetic
21623372
GGPPS_YEASTBTS1genetic
21623372
FKS3_YEASTFKS3genetic
21623372
SPSY_YEASTSPE4genetic
21623372
MHT1_YEASTMHT1genetic
21623372
NDI1_YEASTNDI1genetic
21623372
GCSH_YEASTGCV3genetic
21623372
COQ7_YEASTCAT5genetic
21623372
INO1_YEASTINO1genetic
21623372
UGPA2_YEASTYHL012Wgenetic
21623372
ADH2_YEASTADH2genetic
21623372
COX6_YEASTCOX6genetic
21623372
KAD2_YEASTADK1genetic
21623372
ACON2_YEASTACO2genetic
21623372
GCSP_YEASTGCV2genetic
21623372
FOLE_YEASTMET7genetic
21623372
IDHC_YEASTIDP2genetic
21623372
CY1_YEASTCYT1genetic
21623372
MET5_YEASTMET5genetic
21623372
ODO2_YEASTKGD2genetic
21623372
ARE1_YEASTARE1genetic
21623372
YEH1_YEASTYEH1genetic
21623372
GLRX3_YEASTGRX3genetic
21623372
IPT1_YEASTIPT1genetic
21623372
SSD1_YEASTSSD1genetic
21987634
CANB_YEASTCNB1genetic
21987634
MNE1_YEASTMNE1genetic
27708008
RNY1_YEASTRNY1genetic
27708008
OPY2_YEASTOPY2genetic
27708008
IMG2_YEASTIMG2genetic
27708008
UME6_YEASTUME6genetic
27708008
MRM2_YEASTMRM2genetic
27708008
QCR9_YEASTQCR9genetic
27708008
MRX5_YEASTYJL147Cgenetic
27708008
PABC_YEASTABZ2genetic
27708008
ASE1_YEASTASE1genetic
27708008
HAP5_YEASTHAP5genetic
27708008
COX10_YEASTCOX10genetic
27708008
MMT2_YEASTMMT2genetic
27708008
ASNS1_YEASTASN1genetic
27708008
LHX4_HUMANLHX4physical
27107014
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of FOLC_YEAST

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Related Literatures of Post-Translational Modification

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