| UniProt ID | ASE1_YEAST | |
|---|---|---|
| UniProt AC | P50275 | |
| Protein Name | Anaphase spindle elongation protein | |
| Gene Name | ASE1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 885 | |
| Subcellular Localization | Cytoplasm, cytoskeleton, spindle . | |
| Protein Description | Required for anaphase spindle elongation.. | |
| Protein Sequence | METATSSPLPIKSRRNSENSGSTTVIPHMNPSLATPLTVSTMVNQSNSKEFMKLTPVRIRDFGSPLKNVSTNYHFLDSENGKGNTMDNMYRENFILISKDLEKLLENLNVIYQNIGYSNTEIITKEKIIFTTISNSIKQFFEQADEELKRLSAENGIEQDILNNILERINDPSGIKTIPDLYIRNAILLQESKTVPQSPKKPLSLLSKKAALDTAKKFVLGSFLPRLRDYLKSLITLKHLIQSVKENLPGLTEADNEAIAEFPELSTLTAYLLQIENGKGDIGLSMKFIIDNRKDILKGSAFKTINEESVKHMNEVIKIYEEEYERRFKSVLTKKVSISSICEQLGTPLATLIGEDFEQDLRSYGEEENSTSEIPNFHPVDRERMSKIDITLEKLQAIHKERADKKRLLMEQCQKLWTRLKISQEYIKTFMRNNSSLSTESLGRISKEVMRLEAMKKKLIKKLISDSWDKIQELWRTLQYSEESRSKFIIVFEELRNSATTLQEDELLLETCENELKRLEEKLTLYKPILKLISDFESLQEDQEFLERSSKDSSRLLSRNSHKILLTEEKMRKRITRHFPRVINDLRIKLEEADGLFDQPFLFKGKPLSEAIDIQQQEIEAKYPRCRVRMQRSKKGKCGANKENKVIKNTFKATESSIRVPIGLNLNDANITYKTPSKKTIQGLTKNDLSQENSLARHMQGTTKLSSPNRRATRLLAPTVISRNSKGNIERPTLNRNRSSDLSSSPRINHTHGEHAVKPRQLFPIPLNKVDTKGSHIPQLTKEKALELLKRSTGTTGKENVRSPERKSSLEDYAQKLSSPYKEPEHSIYKLSMSPEGKFQLNIQQKDIESGFDDTSMMEDENDKDFITWKNEQVSKLNGFSFTDI | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 6 | Phosphorylation | --METATSSPLPIKS --CCCCCCCCCCCCC | 27.74 | 28152593 | |
| 7 | Phosphorylation | -METATSSPLPIKSR -CCCCCCCCCCCCCC | 26.54 | 28152593 | |
| 17 | Phosphorylation | PIKSRRNSENSGSTT CCCCCCCCCCCCCCE | 36.02 | 28889911 | |
| 22 | Phosphorylation | RNSENSGSTTVIPHM CCCCCCCCCEEECCC | 22.26 | 19779198 | |
| 32 | Phosphorylation | VIPHMNPSLATPLTV EECCCCHHHCCCEEH | 26.15 | 19779198 | |
| 55 | Phosphorylation | SKEFMKLTPVRIRDF CHHHHHCCCEEEECC | 17.77 | 21440633 | |
| 64 | Phosphorylation | VRIRDFGSPLKNVST EEEECCCCCCCCCCC | 27.36 | 21440633 | |
| 198 | Phosphorylation | ESKTVPQSPKKPLSL CCCCCCCCCCCCHHH | 32.39 | 20377248 | |
| 320 | Phosphorylation | MNEVIKIYEEEYERR HHHHHHHHHHHHHHH | 16.58 | 25704821 | |
| 337 | Phosphorylation | SVLTKKVSISSICEQ HHHCCCCCHHHHHHH | 26.15 | 28889911 | |
| 524 | Phosphorylation | KRLEEKLTLYKPILK HHHHHHHHHHHHHHH | 38.83 | 28889911 | |
| 650 | Phosphorylation | ENKVIKNTFKATESS CCCHHHHHHCCCCCC | 22.85 | 27017623 | |
| 657 | Phosphorylation | TFKATESSIRVPIGL HHCCCCCCEEEEEEC | 14.26 | 27017623 | |
| 675 | Phosphorylation | DANITYKTPSKKTIQ CCCCEEECCCCCCCC | 23.52 | 17562791 | |
| 680 | Phosphorylation | YKTPSKKTIQGLTKN EECCCCCCCCCCCCC | 23.44 | 17765685 | |
| 690 | Phosphorylation | GLTKNDLSQENSLAR CCCCCCCCHHHHHHH | 38.01 | 21440633 | |
| 694 | Phosphorylation | NDLSQENSLARHMQG CCCCHHHHHHHHHHC | 23.74 | 21440633 | |
| 707 | Phosphorylation | QGTTKLSSPNRRATR HCCCCCCCCCHHHHH | 36.31 | 21440633 | |
| 733 | Phosphorylation | KGNIERPTLNRNRSS CCCCCCCCCCCCCCC | 42.77 | 28889911 | |
| 739 | Phosphorylation | PTLNRNRSSDLSSSP CCCCCCCCCCCCCCC | 31.58 | 23749301 | |
| 740 | Phosphorylation | TLNRNRSSDLSSSPR CCCCCCCCCCCCCCC | 39.06 | 23749301 | |
| 744 | Phosphorylation | NRSSDLSSSPRINHT CCCCCCCCCCCCCCC | 52.22 | 28889911 | |
| 745 | Phosphorylation | RSSDLSSSPRINHTH CCCCCCCCCCCCCCC | 18.15 | 23749301 | |
| 803 | Phosphorylation | TGKENVRSPERKSSL CCCHHCCCHHHHCHH | 27.16 | 17562791 | |
| 809 | Phosphorylation | RSPERKSSLEDYAQK CCHHHHCHHHHHHHH | 38.52 | 17765685 | |
| 818 | Phosphorylation | EDYAQKLSSPYKEPE HHHHHHCCCCCCCCC | 35.98 | 19779198 | |
| 819 | Phosphorylation | DYAQKLSSPYKEPEH HHHHHCCCCCCCCCC | 42.56 | 21440633 | |
| 821 | Phosphorylation | AQKLSSPYKEPEHSI HHHCCCCCCCCCCCE | 29.90 | 19779198 | |
| 829 | Phosphorylation | KEPEHSIYKLSMSPE CCCCCCEEEEECCCC | 14.64 | 19779198 | |
| 832 | Phosphorylation | EHSIYKLSMSPEGKF CCCEEEEECCCCCCE | 17.05 | 21440633 | |
| 834 | Phosphorylation | SIYKLSMSPEGKFQL CEEEEECCCCCCEEE | 19.20 | 21440633 | |
| 855 | Phosphorylation | IESGFDDTSMMEDEN HHCCCCCCCCCCCCC | 21.99 | 21551504 | |
| 856 | Phosphorylation | ESGFDDTSMMEDEND HCCCCCCCCCCCCCC | 24.11 | 21551504 | |
| 881 | Phosphorylation | VSKLNGFSFTDI--- HHHCCCCCCCCC--- | 28.74 | 21440633 |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ASE1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ASE1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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