LSM12_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: LSM12_YEAST
• UniProt AC: P38828
• Protein Name: Protein LSM12
• Gene Name: LSM12
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 187
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Sequence: MSVSLEQTLGFRIKVTNVLDVVTEGRLYSFNSSNNTLTIQTTKKNQSPQNFKVIKCTFIKHLEVIGDKPSFNSFKKQQIKPSYVNVERVEKLLKESVIASKKKELLRGKGVSAEGQFIFDQIFKTIGDTKWVAKDIIILDDVKVQPPYKVEDIKVLHEGSNQSITLIQRIVERSWEQLEQDDGRKGG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSVSLEQTL ------CCCCHHHHH	22.03	22814378
52	Acetylation	NQSPQNFKVIKCTFI CCCCCCEEEEEEEEE	51.07	22865919
70	Phosphorylation	EVIGDKPSFNSFKKQ EEECCCCCCCHHCHH	42.68	20377248
73	Phosphorylation	GDKPSFNSFKKQQIK CCCCCCCHHCHHCCC	36.11	20377248
75	Acetylation	KPSFNSFKKQQIKPS CCCCCHHCHHCCCCC	49.87	24489116

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of LSM12_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of LSM12_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of LSM12_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ACA2_YEAST	CST6	physical	16554755
SSB2_YEAST	SSB2	physical	16554755
HSP82_YEAST	HSP82	physical	16554755
ENO2_YEAST	ENO2	physical	16429126
HSP42_YEAST	HSP42	physical	16429126
PBP1_YEAST	PBP1	physical	16429126
PBP4_YEAST	PBP4	physical	16702403
PBP1_YEAST	PBP1	physical	16702403
PBP1_YEAST	PBP1	physical	11283351
EDC3_YEAST	EDC3	genetic	18408161
LRS4_YEAST	LRS4	genetic	19061648
DOA1_YEAST	DOA1	genetic	19061648
THP2_YEAST	THP2	genetic	19061648
ELP1_YEAST	IKI3	genetic	19061648
ERF3_YEAST	SUP35	genetic	19061648
HIR2_YEAST	HIR2	genetic	19061648
PP12_YEAST	GLC7	genetic	19061648
PBP1_YEAST	PBP1	physical	18719252
DIG1_YEAST	DIG1	physical	18719252
DIG2_YEAST	DIG2	physical	18719252
IGO1_YEAST	IGO1	physical	20471941
RS8A_YEAST	RPS8A	genetic	27708008
RS8B_YEAST	RPS8A	genetic	27708008
TFS2_YEAST	DST1	genetic	27708008
HUR1_YEAST	HUR1	genetic	27708008
RL26B_YEAST	RPL26B	genetic	27708008
VPS53_YEAST	VPS53	genetic	27708008
LSM1_YEAST	LSM1	genetic	27708008
NU133_YEAST	NUP133	genetic	27708008
RS3A2_YEAST	RPS1B	genetic	27708008
ADE_YEAST	AAH1	genetic	27708008
BUD21_YEAST	BUD21	genetic	27708008
SFL1_YEAST	SFL1	genetic	27708008
SPEE_YEAST	SPE3	genetic	27708008
RL36A_YEAST	RPL36A	genetic	29158977
PBP1_YEAST	PBP1	physical	25073155
PBP4_YEAST	PBP4	physical	25073155
PABP_YEAST	PAB1	physical	25073155
YRA1_YEAST	YRA1	physical	25073155
STM1_YEAST	STM1	physical	25073155
H4_YEAST	HHF1	physical	25073155
CEP76_HUMAN	CEP76	physical	27107014
NUP60_YEAST	NUP60	genetic	29674565
TFS2_YEAST	DST1	genetic	29674565
NU133_YEAST	NUP133	genetic	29674565
RS7B_YEAST	RPS7B	genetic	29674565
PSH1_YEAST	PSH1	genetic	29674565
DPOD_YEAST	POL3	genetic	29674565
TRS23_YEAST	TRS23	genetic	29674565
STS1_YEAST	STS1	genetic	29674565
BET3_YEAST	BET3	genetic	29674565
BUD31_YEAST	BUD31	genetic	29674565
ICE2_YEAST	ICE2	genetic	29674565
TIM16_YEAST	PAM16	genetic	29674565
CTF18_YEAST	CTF18	genetic	29674565
NAB3_YEAST	NAB3	genetic	29674565
PUS1_YEAST	PUS1	genetic	29674565
BRR1_YEAST	BRR1	genetic	29674565
TSC3_YEAST	TSC3	genetic	29674565
SWC5_YEAST	SWC5	genetic	29674565
TCPZ_YEAST	CCT6	genetic	29674565
RSP5_YEAST	RSP5	genetic	29674565
HUR1_YEAST	HUR1	genetic	29674565
MLP1_YEAST	MLP1	genetic	29674565
DPH6_YEAST	DPH6	genetic	29674565
GYP1_YEAST	GYP1	genetic	29674565

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.