UniProt ID | HSP82_YEAST | |
---|---|---|
UniProt AC | P02829 | |
Protein Name | ATP-dependent molecular chaperone HSP82 | |
Gene Name | HSP82 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 709 | |
Subcellular Localization | Cytoplasm . | |
Protein Description | Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. The nucleotide-free form of the dimer is found in an open conformation in which the N-termini are not dimerized and the complex is ready for client protein binding. Binding of ATP induces large conformational changes, resulting in the formation of a ring-like closed structure in which the N-terminal domains associate intramolecularly with the middle domain and also dimerize with each other, stimulating their intrinsic ATPase activity and acting as a clamp on the substrate. Finally, ATP hydrolysis results in the release of the substrate. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Required for growth at high temperatures.. | |
Protein Sequence | MASETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEVPIPEEEKKDEEKKDEEKKDEDDKKPKLEEVDEEEEKKPKTKKVKEEVQEIEELNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDITKDFELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNIDEDEETETAPEASTAAPVEEVPADTEMEEVD | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
|
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
36 | Phosphorylation | IFLRELISNASDALD HHHHHHHHCCHHHHH | 38.68 | 28152593 | |
39 | Phosphorylation | RELISNASDALDKIR HHHHHCCHHHHHHHH | 27.89 | 21440633 | |
44 | 2-Hydroxyisobutyrylation | NASDALDKIRYKSLS CCHHHHHHHHHHCCC | 29.90 | - | |
44 | Acetylation | NASDALDKIRYKSLS CCHHHHHHHHHHCCC | 29.90 | 24489116 | |
44 | Ubiquitination | NASDALDKIRYKSLS CCHHHHHHHHHHCCC | 29.90 | 23749301 | |
48 | 2-Hydroxyisobutyrylation | ALDKIRYKSLSDPKQ HHHHHHHHCCCCHHH | 34.76 | - | |
51 | Phosphorylation | KIRYKSLSDPKQLET HHHHHCCCCHHHCCC | 59.98 | 21440633 | |
54 | Acetylation | YKSLSDPKQLETEPD HHCCCCHHHCCCCCC | 72.93 | 24489116 | |
54 | Ubiquitination | YKSLSDPKQLETEPD HHCCCCHHHCCCCCC | 72.93 | 23749301 | |
69 | Ubiquitination | LFIRITPKPEQKVLE EEEECCCCHHHCEEE | 53.16 | 23749301 | |
73 | 2-Hydroxyisobutyrylation | ITPKPEQKVLEIRDS CCCCHHHCEEEEHHC | 47.31 | - | |
80 | Phosphorylation | KVLEIRDSGIGMTKA CEEEEHHCCCCCCHH | 23.59 | 21440633 | |
86 | Acetylation | DSGIGMTKAELINNL HCCCCCCHHHHHHHH | 30.85 | 24489116 | |
86 | Succinylation | DSGIGMTKAELINNL HCCCCCCHHHHHHHH | 30.85 | 23954790 | |
86 | Ubiquitination | DSGIGMTKAELINNL HCCCCCCHHHHHHHH | 30.85 | 23749301 | |
98 | Acetylation | NNLGTIAKSGTKAFM HHHHHHHHHCHHHHH | 45.64 | 24489116 | |
98 | Succinylation | NNLGTIAKSGTKAFM HHHHHHHHHCHHHHH | 45.64 | 23954790 | |
98 | Ubiquitination | NNLGTIAKSGTKAFM HHHHHHHHHCHHHHH | 45.64 | 23749301 | |
102 | 2-Hydroxyisobutyrylation | TIAKSGTKAFMEALS HHHHHCHHHHHHHHH | 43.05 | - | |
178 | Acetylation | TILRLFLKDDQLEYL HHHHHEECHHHHHHH | 52.50 | 24489116 | |
178 | Succinylation | TILRLFLKDDQLEYL HHHHHEECHHHHHHH | 52.50 | 23954790 | |
178 | Ubiquitination | TILRLFLKDDQLEYL HHHHHEECHHHHHHH | 52.50 | 23749301 | |
188 | Acetylation | QLEYLEEKRIKEVIK HHHHHHHHHHHHHHH | 50.47 | 24489116 | |
188 | Succinylation | QLEYLEEKRIKEVIK HHHHHHHHHHHHHHH | 50.47 | 23954790 | |
188 | Ubiquitination | QLEYLEEKRIKEVIK HHHHHHHHHHHHHHH | 50.47 | 24961812 | |
195 | 2-Hydroxyisobutyrylation | KRIKEVIKRHSEFVA HHHHHHHHHHHHHCC | 49.59 | - | |
195 | Acetylation | KRIKEVIKRHSEFVA HHHHHHHHHHHHHCC | 49.59 | 25381059 | |
211 | Ubiquitination | PIQLVVTKEVEKEVP EEEEEEECCCCCCCC | 48.42 | 22106047 | |
215 | Acetylation | VVTKEVEKEVPIPEE EEECCCCCCCCCCHH | 70.01 | 24489116 | |
215 | Succinylation | VVTKEVEKEVPIPEE EEECCCCCCCCCCHH | 70.01 | 23954790 | |
224 | Acetylation | VPIPEEEKKDEEKKD CCCCHHHCCCHHHHH | 69.66 | 24489116 | |
243 | Acetylation | DEDDKKPKLEEVDEE CCCCCCCCHHHCCHH | 76.92 | 24489116 | |
253 | Acetylation | EVDEEEEKKPKTKKV HCCHHHHHCCCCHHH | 77.11 | 24489116 | |
253 | Ubiquitination | EVDEEEEKKPKTKKV HCCHHHHHCCCCHHH | 77.11 | 22817900 | |
254 | Acetylation | VDEEEEKKPKTKKVK CCHHHHHCCCCHHHH | 55.84 | 25381059 | |
254 | Ubiquitination | VDEEEEKKPKTKKVK CCHHHHHCCCCHHHH | 55.84 | 22817900 | |
256 | 2-Hydroxyisobutyrylation | EEEEKKPKTKKVKEE HHHHHCCCCHHHHHH | 80.16 | - | |
256 | Ubiquitination | EEEEKKPKTKKVKEE HHHHHCCCCHHHHHH | 80.16 | 22817900 | |
258 | Ubiquitination | EEKKPKTKKVKEEVQ HHHCCCCHHHHHHHH | 62.79 | 22817900 | |
259 | Acetylation | EKKPKTKKVKEEVQE HHCCCCHHHHHHHHH | 64.86 | 24489116 | |
259 | Ubiquitination | EKKPKTKKVKEEVQE HHCCCCHHHHHHHHH | 64.86 | 22817900 | |
261 | Ubiquitination | KPKTKKVKEEVQEIE CCCCHHHHHHHHHHH | 57.97 | 22817900 | |
272 | Ubiquitination | QEIEELNKTKPLWTR HHHHHHHCCCCCCCC | 71.23 | 17644757 | |
274 | Ubiquitination | IEELNKTKPLWTRNP HHHHHCCCCCCCCCH | 39.46 | 23749301 | |
278 | Phosphorylation | NKTKPLWTRNPSDIT HCCCCCCCCCHHHCC | 28.40 | 24961812 | |
282 | Phosphorylation | PLWTRNPSDITQEEY CCCCCCHHHCCHHHH | 45.23 | 21082442 | |
285 | Phosphorylation | TRNPSDITQEEYNAF CCCHHHCCHHHHHHH | 34.61 | 28889911 | |
294 | Ubiquitination | EEYNAFYKSISNDWE HHHHHHHHHHCCCCC | 34.55 | 23749301 | |
295 | Phosphorylation | EYNAFYKSISNDWED HHHHHHHHHCCCCCC | 21.62 | 22369663 | |
297 | Phosphorylation | NAFYKSISNDWEDPL HHHHHHHCCCCCCCE | 35.51 | 22369663 | |
307 | Ubiquitination | WEDPLYVKHFSVEGQ CCCCEEEEEEEEECE | 25.94 | 23749301 | |
325 | 2-Hydroxyisobutyrylation | RAILFIPKRAPFDLF EEEEEEECCCCCCHH | 57.27 | - | |
325 | Acetylation | RAILFIPKRAPFDLF EEEEEEECCCCCCHH | 57.27 | 24489116 | |
325 | Succinylation | RAILFIPKRAPFDLF EEEEEEECCCCCCHH | 57.27 | 23954790 | |
325 | Ubiquitination | RAILFIPKRAPFDLF EEEEEEECCCCCCHH | 57.27 | 23749301 | |
334 | Phosphorylation | APFDLFESKKKKNNI CCCCHHHCCCCCCCE | 42.30 | 25521595 | |
335 | Acetylation | PFDLFESKKKKNNIK CCCHHHCCCCCCCEE | 62.51 | 24489116 | |
335 | Succinylation | PFDLFESKKKKNNIK CCCHHHCCCCCCCEE | 62.51 | 23954790 | |
335 | Ubiquitination | PFDLFESKKKKNNIK CCCHHHCCCCCCCEE | 62.51 | 17644757 | |
336 | Acetylation | FDLFESKKKKNNIKL CCHHHCCCCCCCEEE | 77.56 | 24489116 | |
336 | Ubiquitination | FDLFESKKKKNNIKL CCHHHCCCCCCCEEE | 77.56 | 17644757 | |
342 | Acetylation | KKKKNNIKLYVRRVF CCCCCCEEEEEEEEE | 35.57 | 22865919 | |
342 | Ubiquitination | KKKKNNIKLYVRRVF CCCCCCEEEEEEEEE | 35.57 | 23749301 | |
366 | Ubiquitination | PEWLSFVKGVVDSED HHHHHHHCCCCCCCC | 43.93 | 17644757 | |
371 | Phosphorylation | FVKGVVDSEDLPLNL HHCCCCCCCCCCCCC | 22.77 | 22369663 | |
379 | Phosphorylation | EDLPLNLSREMLQQN CCCCCCCCHHHHHHC | 25.73 | 22369663 | |
387 | Acetylation | REMLQQNKIMKVIRK HHHHHHCHHHHHHHH | 39.58 | 24489116 | |
387 | Succinylation | REMLQQNKIMKVIRK HHHHHHCHHHHHHHH | 39.58 | 23954790 | |
387 | Ubiquitination | REMLQQNKIMKVIRK HHHHHHCHHHHHHHH | 39.58 | 23749301 | |
390 | Acetylation | LQQNKIMKVIRKNIV HHHCHHHHHHHHHHH | 37.67 | 24489116 | |
390 | Ubiquitination | LQQNKIMKVIRKNIV HHHCHHHHHHHHHHH | 37.67 | 22817900 | |
398 | Ubiquitination | VIRKNIVKKLIEAFN HHHHHHHHHHHHHHH | 37.76 | 17644757 | |
399 | Acetylation | IRKNIVKKLIEAFNE HHHHHHHHHHHHHHH | 43.75 | 24489116 | |
399 | Ubiquitination | IRKNIVKKLIEAFNE HHHHHHHHHHHHHHH | 43.75 | 17644757 | |
416 | Ubiquitination | EDSEQFEKFYSAFSK CCHHHHHHHHHHHHH | 51.39 | 23749301 | |
419 | Phosphorylation | EQFEKFYSAFSKNIK HHHHHHHHHHHHCCC | 26.43 | 21440633 | |
423 | Acetylation | KFYSAFSKNIKLGVH HHHHHHHHCCCCCCC | 57.13 | 24489116 | |
426 | 2-Hydroxyisobutyrylation | SAFSKNIKLGVHEDT HHHHHCCCCCCCHHH | 48.89 | - | |
426 | Acetylation | SAFSKNIKLGVHEDT HHHHHCCCCCCCHHH | 48.89 | 22865919 | |
426 | Ubiquitination | SAFSKNIKLGVHEDT HHHHHCCCCCCCHHH | 48.89 | 23749301 | |
433 | Phosphorylation | KLGVHEDTQNRAALA CCCCCHHHHCHHHHH | 25.43 | 20377248 | |
441 | 2-Hydroxyisobutyrylation | QNRAALAKLLRYNST HCHHHHHHHHHHCCC | 49.24 | - | |
441 | Acetylation | QNRAALAKLLRYNST HCHHHHHHHHHHCCC | 49.24 | 24489116 | |
441 | Ubiquitination | QNRAALAKLLRYNST HCHHHHHHHHHHCCC | 49.24 | 23749301 | |
445 | Phosphorylation | ALAKLLRYNSTKSVD HHHHHHHHCCCCCHH | 17.27 | 21440633 | |
447 | Phosphorylation | AKLLRYNSTKSVDEL HHHHHHCCCCCHHHH | 28.42 | 21440633 | |
448 | Phosphorylation | KLLRYNSTKSVDELT HHHHHCCCCCHHHHH | 24.57 | 21440633 | |
449 | Acetylation | LLRYNSTKSVDELTS HHHHCCCCCHHHHHH | 48.58 | 24489116 | |
449 | Ubiquitination | LLRYNSTKSVDELTS HHHHCCCCCHHHHHH | 48.58 | 23749301 | |
450 | Phosphorylation | LRYNSTKSVDELTSL HHHCCCCCHHHHHHH | 34.58 | 22369663 | |
455 | Phosphorylation | TKSVDELTSLTDYVT CCCHHHHHHHHHHHH | 21.46 | 19779198 | |
456 | Phosphorylation | KSVDELTSLTDYVTR CCHHHHHHHHHHHHH | 41.73 | 25752575 | |
458 | Phosphorylation | VDELTSLTDYVTRMP HHHHHHHHHHHHHCC | 25.67 | 19779198 | |
462 | Phosphorylation | TSLTDYVTRMPEHQK HHHHHHHHHCCHHHC | 18.28 | 19779198 | |
469 | 2-Hydroxyisobutyrylation | TRMPEHQKNIYYITG HHCCHHHCCEEEECC | 47.42 | - | |
469 | Acetylation | TRMPEHQKNIYYITG HHCCHHHCCEEEECC | 47.42 | 24489116 | |
469 | Ubiquitination | TRMPEHQKNIYYITG HHCCHHHCCEEEECC | 47.42 | 24961812 | |
472 | Phosphorylation | PEHQKNIYYITGESL CHHHCCEEEECCHHH | 9.75 | 22369663 | |
473 | Phosphorylation | EHQKNIYYITGESLK HHHCCEEEECCHHHH | 6.55 | 22369663 | |
475 | Phosphorylation | QKNIYYITGESLKAV HCCEEEECCHHHHHH | 20.83 | 22369663 | |
478 | Phosphorylation | IYYITGESLKAVEKS EEEECCHHHHHHHHC | 36.19 | 22369663 | |
480 | Acetylation | YITGESLKAVEKSPF EECCHHHHHHHHCCH | 60.71 | 24489116 | |
480 | Ubiquitination | YITGESLKAVEKSPF EECCHHHHHHHHCCH | 60.71 | 24961812 | |
484 | 2-Hydroxyisobutyrylation | ESLKAVEKSPFLDAL HHHHHHHHCCHHHHH | 57.75 | - | |
484 | Acetylation | ESLKAVEKSPFLDAL HHHHHHHHCCHHHHH | 57.75 | 24489116 | |
484 | Ubiquitination | ESLKAVEKSPFLDAL HHHHHHHHCCHHHHH | 57.75 | 23749301 | |
485 | Phosphorylation | SLKAVEKSPFLDALK HHHHHHHCCHHHHHH | 13.84 | 21440633 | |
492 | Acetylation | SPFLDALKAKNFEVL CCHHHHHHHCCCEEE | 60.06 | 24489116 | |
492 | Succinylation | SPFLDALKAKNFEVL CCHHHHHHHCCCEEE | 60.06 | 23954790 | |
492 | Ubiquitination | SPFLDALKAKNFEVL CCHHHHHHHCCCEEE | 60.06 | 23749301 | |
494 | 2-Hydroxyisobutyrylation | FLDALKAKNFEVLFL HHHHHHHCCCEEEEE | 61.66 | - | |
494 | Ubiquitination | FLDALKAKNFEVLFL HHHHHHHCCCEEEEE | 61.66 | 22817900 | |
514 | Ubiquitination | EYAFTQLKEFEGKTL HHHHHHHHHCCCCEE | 51.01 | 17644757 | |
519 | 2-Hydroxyisobutyrylation | QLKEFEGKTLVDITK HHHHCCCCEEEEHHH | 31.33 | - | |
519 | Acetylation | QLKEFEGKTLVDITK HHHHCCCCEEEEHHH | 31.33 | 24489116 | |
519 | Ubiquitination | QLKEFEGKTLVDITK HHHHCCCCEEEEHHH | 31.33 | 23749301 | |
526 | Acetylation | KTLVDITKDFELEET CEEEEHHHCCCCCCC | 61.83 | 24489116 | |
533 | Phosphorylation | KDFELEETDEEKAER HCCCCCCCHHHHHHH | 39.06 | 27214570 | |
537 | 2-Hydroxyisobutyrylation | LEETDEEKAEREKEI CCCCHHHHHHHHHHH | 54.20 | - | |
537 | Acetylation | LEETDEEKAEREKEI CCCCHHHHHHHHHHH | 54.20 | 24489116 | |
537 | Ubiquitination | LEETDEEKAEREKEI CCCCHHHHHHHHHHH | 54.20 | 24961812 | |
542 | Acetylation | EEKAEREKEIKEYEP HHHHHHHHHHHHHHH | 71.59 | 24489116 | |
542 | Ubiquitination | EEKAEREKEIKEYEP HHHHHHHHHHHHHHH | 71.59 | 24961812 | |
545 | 2-Hydroxyisobutyrylation | AEREKEIKEYEPLTK HHHHHHHHHHHHHHH | 56.16 | - | |
545 | Acetylation | AEREKEIKEYEPLTK HHHHHHHHHHHHHHH | 56.16 | 24489116 | |
545 | Succinylation | AEREKEIKEYEPLTK HHHHHHHHHHHHHHH | 56.16 | 23954790 | |
545 | Ubiquitination | AEREKEIKEYEPLTK HHHHHHHHHHHHHHH | 56.16 | 23749301 | |
547 | Phosphorylation | REKEIKEYEPLTKAL HHHHHHHHHHHHHHH | 20.18 | 28889911 | |
551 | Phosphorylation | IKEYEPLTKALKEIL HHHHHHHHHHHHHHH | 25.61 | 28889911 | |
552 | 2-Hydroxyisobutyrylation | KEYEPLTKALKEILG HHHHHHHHHHHHHHC | 60.45 | - | |
552 | Acetylation | KEYEPLTKALKEILG HHHHHHHHHHHHHHC | 60.45 | 24489116 | |
552 | Ubiquitination | KEYEPLTKALKEILG HHHHHHHHHHHHHHC | 60.45 | 23749301 | |
555 | 2-Hydroxyisobutyrylation | EPLTKALKEILGDQV HHHHHHHHHHHCCHH | 47.79 | - | |
555 | Acetylation | EPLTKALKEILGDQV HHHHHHHHHHHCCHH | 47.79 | 24489116 | |
555 | Succinylation | EPLTKALKEILGDQV HHHHHHHHHHHCCHH | 47.79 | 23954790 | |
555 | Ubiquitination | EPLTKALKEILGDQV HHHHHHHHHHHCCHH | 47.79 | 23749301 | |
564 | 2-Hydroxyisobutyrylation | ILGDQVEKVVVSYKL HHCCHHEEEEEEEEE | 41.28 | - | |
564 | Acetylation | ILGDQVEKVVVSYKL HHCCHHEEEEEEEEE | 41.28 | 24489116 | |
569 | Phosphorylation | VEKVVVSYKLLDAPA HEEEEEEEEECCCCC | 8.27 | 21440633 | |
570 | 2-Hydroxyisobutyrylation | EKVVVSYKLLDAPAA EEEEEEEEECCCCCH | 34.76 | - | |
570 | Acetylation | EKVVVSYKLLDAPAA EEEEEEEEECCCCCH | 34.76 | 24489116 | |
570 | Succinylation | EKVVVSYKLLDAPAA EEEEEEEEECCCCCH | 34.76 | 23954790 | |
570 | Ubiquitination | EKVVVSYKLLDAPAA EEEEEEEEECCCCCH | 34.76 | 23749301 | |
580 | Phosphorylation | DAPAAIRTGQFGWSA CCCCHHHCCCCCCCC | 29.26 | 28889911 | |
586 | Phosphorylation | RTGQFGWSANMERIM HCCCCCCCCCHHHHH | 15.33 | 22369663 | |
594 | 2-Hydroxyisobutyrylation | ANMERIMKAQALRDS CCHHHHHHHHHHHHC | 34.67 | - | |
594 | Acetylation | ANMERIMKAQALRDS CCHHHHHHHHHHHHC | 34.67 | 25381059 | |
594 | Ubiquitination | ANMERIMKAQALRDS CCHHHHHHHHHHHHC | 34.67 | 23749301 | |
601 | Phosphorylation | KAQALRDSSMSSYMS HHHHHHHCHHHHHHH | 22.85 | 20377248 | |
602 | Phosphorylation | AQALRDSSMSSYMSS HHHHHHCHHHHHHHC | 27.29 | 22369663 | |
604 | Phosphorylation | ALRDSSMSSYMSSKK HHHHCHHHHHHHCCC | 21.92 | 20377248 | |
605 | Phosphorylation | LRDSSMSSYMSSKKT HHHCHHHHHHHCCCE | 19.06 | 22369663 | |
606 | Phosphorylation | RDSSMSSYMSSKKTF HHCHHHHHHHCCCEE | 8.16 | 22369663 | |
608 | Phosphorylation | SSMSSYMSSKKTFEI CHHHHHHHCCCEEEC | 30.67 | 22369663 | |
609 | Phosphorylation | SMSSYMSSKKTFEIS HHHHHHHCCCEEECC | 22.95 | 21551504 | |
610 | 2-Hydroxyisobutyrylation | MSSYMSSKKTFEISP HHHHHHCCCEEECCC | 48.83 | - | |
610 | Succinylation | MSSYMSSKKTFEISP HHHHHHCCCEEECCC | 48.83 | 23954790 | |
610 | Ubiquitination | MSSYMSSKKTFEISP HHHHHHCCCEEECCC | 48.83 | 23749301 | |
611 | 2-Hydroxyisobutyrylation | SSYMSSKKTFEISPK HHHHHCCCEEECCCC | 61.47 | - | |
611 | Ubiquitination | SSYMSSKKTFEISPK HHHHHCCCEEECCCC | 61.47 | 23749301 | |
612 | Phosphorylation | SYMSSKKTFEISPKS HHHHCCCEEECCCCC | 30.18 | 19823750 | |
616 | Phosphorylation | SKKTFEISPKSPIIK CCCEEECCCCCHHHH | 21.05 | 22369663 | |
618 | 2-Hydroxyisobutyrylation | KTFEISPKSPIIKEL CEEECCCCCHHHHHH | 63.17 | - | |
618 | Acetylation | KTFEISPKSPIIKEL CEEECCCCCHHHHHH | 63.17 | 24489116 | |
618 | Succinylation | KTFEISPKSPIIKEL CEEECCCCCHHHHHH | 63.17 | 23954790 | |
618 | Ubiquitination | KTFEISPKSPIIKEL CEEECCCCCHHHHHH | 63.17 | 23749301 | |
619 | Phosphorylation | TFEISPKSPIIKELK EEECCCCCHHHHHHH | 25.39 | 22369663 | |
623 | 2-Hydroxyisobutyrylation | SPKSPIIKELKKRVD CCCCHHHHHHHHHHC | 58.68 | - | |
623 | Acetylation | SPKSPIIKELKKRVD CCCCHHHHHHHHHHC | 58.68 | 24489116 | |
623 | Succinylation | SPKSPIIKELKKRVD CCCCHHHHHHHHHHC | 58.68 | 23954790 | |
623 | Ubiquitination | SPKSPIIKELKKRVD CCCCHHHHHHHHHHC | 58.68 | 23749301 | |
626 | Ubiquitination | SPIIKELKKRVDEGG CHHHHHHHHHHCCCC | 39.36 | 22817900 | |
627 | Acetylation | PIIKELKKRVDEGGA HHHHHHHHHHCCCCC | 70.99 | 24489116 | |
627 | Ubiquitination | PIIKELKKRVDEGGA HHHHHHHHHHCCCCC | 70.99 | 22817900 | |
637 | 2-Hydroxyisobutyrylation | DEGGAQDKTVKDLTK CCCCCCCCHHHHHHH | 43.04 | - | |
637 | Acetylation | DEGGAQDKTVKDLTK CCCCCCCCHHHHHHH | 43.04 | 24489116 | |
637 | Ubiquitination | DEGGAQDKTVKDLTK CCCCCCCCHHHHHHH | 43.04 | 23749301 | |
640 | Acetylation | GAQDKTVKDLTKLLY CCCCCHHHHHHHHHH | 52.86 | 25381059 | |
640 | Succinylation | GAQDKTVKDLTKLLY CCCCCHHHHHHHHHH | 52.86 | 23954790 | |
640 | Ubiquitination | GAQDKTVKDLTKLLY CCCCCHHHHHHHHHH | 52.86 | 22817900 | |
657 | Phosphorylation | ALLTSGFSLDEPTSF HHHHCCCCCCCCCCH | 38.14 | 28889911 | |
663 | Phosphorylation | FSLDEPTSFASRINR CCCCCCCCHHHHHHH | 29.54 | 28889911 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HSP82_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HSP82_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HSP82_YEAST !! |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-657 AND SER-663, ANDMASS SPECTROMETRY. |