DLD1_YEAST - dbPTM
DLD1_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID DLD1_YEAST
UniProt AC P32891
Protein Name D-lactate dehydrogenase [cytochrome] 1, mitochondrial
Gene Name DLD1
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 587
Subcellular Localization Mitochondrion inner membrane .
Protein Description Catalyzes the stereospecific oxidation of D-lactate to pyruvate..
Protein Sequence MLWKRTCTRLIKPIAQPRGRLVRRSCYRYASTGTGSTDSSSQWLKYSVIASSATLFGYLFAKNLYSRETKEDLIEKLEMVKKIDPVNSTLKLSSLDSPDYLHDPVKIDKVVEDLKQVLGNKPENYSDAKSDLDAHSDTYFNTHHPSPEQRPRIILFPHTTEEVSKILKICHDNNMPVVPFSGGTSLEGHFLPTRIGDTITVDLSKFMNNVVKFDKLDLDITVQAGLPWEDLNDYLSDHGLMFGCDPGPGAQIGGCIANSCSGTNAYRYGTMKENIINMTIVLPDGTIVKTKKRPRKSSAGYNLNGLFVGSEGTLGIVTEATVKCHVKPKAETVAVVSFDTIKDAAACASNLTQSGIHLNAMELLDENMMKLINASESTDRCDWVEKPTMFFKIGGRSPNIVNALVDEVKAVAQLNHCNSFQFAKDDDEKLELWEARKVALWSVLDADKSKDKSAKIWTTDVAVPVSQFDKVIHETKKDMQASKLINAIVGHAGDGNFHAFIVYRTPEEHETCSQLVDRMVKRALNAEGTCTGEHGVGIGKREYLLEELGEAPVDLMRKIKLAIDPKRIMNPDKIFKTDPNEPANDYR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
88PhosphorylationKKIDPVNSTLKLSSL
HCCCCCCCCEEECCC		35.0421440633
89PhosphorylationKIDPVNSTLKLSSLD
CCCCCCCCEEECCCC		23.7819823750
165AcetylationHTTEEVSKILKICHD
CCHHHHHHHHHHHHC		58.1824489116
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of DLD1_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of DLD1_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of DLD1_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
PTH2_YEASTPTH2genetic
20093466
HIR1_YEASTHIR1genetic
20093466
DOT1_YEASTDOT1genetic
20093466
YFH6_YEASTYFR006Wgenetic
20093466
YJQ3_YEASTYJL163Cgenetic
20093466
THDH_YEASTILV1genetic
21623372
ERG2_YEASTERG2genetic
21623372
CEM1_YEASTCEM1genetic
21623372
PRP6_YEASTPRP6genetic
27708008
UTP6_YEASTUTP6genetic
27708008
PTH2_YEASTPTH2genetic
27708008
NPL4_YEASTNPL4genetic
27708008
CP56_YEASTDIT2genetic
27708008
DOT1_YEASTDOT1genetic
27708008
YFH6_YEASTYFR006Wgenetic
27708008
MTC1_YEASTMTC1genetic
27708008
YJQ3_YEASTYJL163Cgenetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of DLD1_YEAST

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Related Literatures of Post-Translational Modification

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