| UniProt ID | THDH_YEAST | |
|---|---|---|
| UniProt AC | P00927 | |
| Protein Name | Threonine dehydratase, mitochondrial | |
| Gene Name | ILV1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 576 | |
| Subcellular Localization | Mitochondrion . | |
| Protein Description | ||
| Protein Sequence | MSATLLKQPLCTVVRQGKQSKVSGLNLLRLKAHLHRQHLSPSLIKLHSELKLDELQTDNTPDYVRLVLRSSVYDVINESPISQGVGLSSRLNTNVILKREDLLPVFSFKLRGAYNMIAKLDDSQRNQGVIACSAGNHAQGVAFAAKHLKIPATIVMPVCTPSIKYQNVSRLGSQVVLYGNDFDEAKAECAKLAEERGLTNIPPFDHPYVIAGQGTVAMEILRQVRTANKIGAVFVPVGGGGLIAGIGAYLKRVAPHIKIIGVETYDAATLHNSLQRNQRTPLPVVGTFADGTSVRMIGEETFRVAQQVVDEVVLVNTDEICAAVKDIFEDTRSIVEPSGALSVAGMKKYISTVHPEIDHTKNTYVPILSGANMNFDRLRFVSERAVLGEGKEVFMLVTLPDVPGAFKKMQKIIHPRSVTEFSYRYNEHRHESSSEVPKAYIYTSFSVVDREKEIKQVMQQLNALGFEAVDISDNELAKSHGRYLVGGASKVPNERIISFEFPERPGALTRFLGGLSDSWNLTLFHYRNHGADIGKVLAGISVPPRENLTFQKFLEDLGYTYHDETDNTVYQKFLKY | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 51 | Acetylation | IKLHSELKLDELQTD HHHHCCCCCHHHCCC | 50.25 | 24489116 | |
| 109 | N6-(pyridoxal phosphate)lysine | LLPVFSFKLRGAYNM HHHHEEEEECHHHHH | 35.76 | - | |
| 109 | Acetylation | LLPVFSFKLRGAYNM HHHHEEEEECHHHHH | 35.76 | 24489116 | |
| 109 | Other | LLPVFSFKLRGAYNM HHHHEEEEECHHHHH | 35.76 | - | |
| 119 | Acetylation | GAYNMIAKLDDSQRN HHHHHHEECCHHHHC | 41.34 | 24489116 | |
| 146 | Acetylation | QGVAFAAKHLKIPAT HHHHHHHHHCCCCEE | 46.14 | 24489116 | |
| 186 | Acetylation | GNDFDEAKAECAKLA CCCHHHHHHHHHHHH | 42.54 | 24489116 | |
| 191 | Acetylation | EAKAECAKLAEERGL HHHHHHHHHHHHHCC | 60.95 | 22865919 | |
| 361 | Acetylation | HPEIDHTKNTYVPIL CCCCCCCCCCEEEEC | 43.82 | 24489116 | |
| 363 | Phosphorylation | EIDHTKNTYVPILSG CCCCCCCCEEEECCC | 27.70 | 27017623 | |
| 364 | Phosphorylation | IDHTKNTYVPILSGA CCCCCCCEEEECCCC | 17.39 | 27017623 | |
| 369 | Phosphorylation | NTYVPILSGANMNFD CCEEEECCCCCCCHH | 36.26 | 27017623 | |
| 417 | Phosphorylation | QKIIHPRSVTEFSYR HHHCCCCCHHHHECC | 37.53 | 22369663 | |
| 419 | Phosphorylation | IIHPRSVTEFSYRYN HCCCCCHHHHECCCC | 32.34 | 22369663 | |
| 422 | Phosphorylation | PRSVTEFSYRYNEHR CCCHHHHECCCCCCC | 11.50 | 22369663 | |
| 423 | Phosphorylation | RSVTEFSYRYNEHRH CCHHHHECCCCCCCC | 23.57 | 22369663 | |
| 490 | Acetylation | YLVGGASKVPNERII EECCCCCCCCCCEEE | 62.26 | 24489116 | |
| 498 | Phosphorylation | VPNERIISFEFPERP CCCCEEEEEECCCCC | 19.15 | 22369663 | |
| 572 | Acetylation | TDNTVYQKFLKY--- CCCCCHHHHHCC--- | 34.67 | 24489116 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of THDH_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of THDH_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of THDH_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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