OCA4_YEAST - dbPTM
OCA4_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID OCA4_YEAST
UniProt AC P25366
Protein Name Protein OCA4
Gene Name OCA4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 362
Subcellular Localization
Protein Description Required for replication of Brome mosaic virus (BMV)..
Protein Sequence MLVPPANFGIAEEGIYRCSKVETLNLSFLETLNLKTAIFIGGQEPSKFFKDFFTRSSIKWIVLRMSDFSAAAVPVKSSSVSNANLYSNNNSTLSLQEEKKKSTANGSQNSTTGDPVIQEELAYHLTDNDDLMLIKSTCLKRTFKTLLNVDNYNVLLVDKTALVIGILRKIQKWNIASIINEYRLFSGKNRNYFAETFLEIINIEIEQEKDNKTIVDNKAKKLPLENNRTHSIEYKANSGKLIRVNEDDLCREPEVPQRLLTLINQIETKVKNNKVLQVSGVLGDDLKKTSSDLGIFGHRYRLAFNKKENGDYGYYKARGKDNVKIRIPCDSELPDWFRFQRDLWEKENVPEEHHFYREHIFT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
16PhosphorylationGIAEEGIYRCSKVET
CCCCCCCCCCCCCEE		19.2030377154
77PhosphorylationAAAVPVKSSSVSNAN
CEECEECCCCCCCCE		28.2522369663
78PhosphorylationAAVPVKSSSVSNANL
EECEECCCCCCCCEE		29.1022369663
79PhosphorylationAVPVKSSSVSNANLY
ECEECCCCCCCCEEE		36.3322369663
81PhosphorylationPVKSSSVSNANLYSN
EECCCCCCCCEEECC		31.9722369663
86PhosphorylationSVSNANLYSNNNSTL
CCCCCEEECCCCCCC		14.7922369663
87PhosphorylationVSNANLYSNNNSTLS
CCCCEEECCCCCCCC		35.9322369663
91PhosphorylationNLYSNNNSTLSLQEE
EEECCCCCCCCCCHH		32.6122369663
92PhosphorylationLYSNNNSTLSLQEEK
EECCCCCCCCCCHHH		23.6122369663
94PhosphorylationSNNNSTLSLQEEKKK
CCCCCCCCCCHHHHH		28.2622369663
145PhosphorylationCLKRTFKTLLNVDNY
HHHHHHHHHHCCCCC		32.0819795423
152PhosphorylationTLLNVDNYNVLLVDK
HHHCCCCCCEEEECH		11.3719823750
229PhosphorylationLPLENNRTHSIEYKA
CCCCCCCCEEEEEEE		23.3026447709
231PhosphorylationLENNRTHSIEYKANS
CCCCCCEEEEEEECC		19.2630377154
234PhosphorylationNRTHSIEYKANSGKL
CCCEEEEEEECCCCE		17.4626447709
238PhosphorylationSIEYKANSGKLIRVN
EEEEEECCCCEEEEC		42.0126447709
279PhosphorylationNNKVLQVSGVLGDDL
CCCEEEEEEEECCHH		15.3822369663
289PhosphorylationLGDDLKKTSSDLGIF
ECCHHHHCHHCCCCC		31.6922369663
290PhosphorylationGDDLKKTSSDLGIFG
CCHHHHCHHCCCCCC		30.6322369663
291PhosphorylationDDLKKTSSDLGIFGH
CHHHHCHHCCCCCCC		41.9322369663
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of OCA4_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of OCA4_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of OCA4_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
OCA1_YEASTOCA1physical
16429126
SIW14_YEASTSIW14physical
16429126
OCA5_YEASTOCA5physical
16429126
OCA1_YEASTOCA1physical
11283351
OCA5_YEASTOCA5physical
18467557
OCA5_YEASTOCA5genetic
19176519
GCN2_YEASTGCN2genetic
19176519
SIW14_YEASTSIW14genetic
21409566
HCM1_YEASTHCM1genetic
21127252
OCA5_YEASTOCA5physical
22615397
RS6A_YEASTRPS6Bgenetic
27708008
RS6B_YEASTRPS6Bgenetic
27708008
LSM6_YEASTLSM6genetic
27708008
CBF1_YEASTCBF1genetic
27708008
DNM1_YEASTDNM1genetic
27708008
ADY4_YEASTADY4genetic
27708008
HRB1_YEASTHRB1genetic
27708008
RRP6_YEASTRRP6genetic
27708008
MSS18_YEASTMSS18genetic
27708008
YAJ9_YEASTYAR029Wgenetic
27708008
H4_YEASTHHF1genetic
27708008
MBA1_YEASTMBA1genetic
27708008
VAM6_YEASTVAM6genetic
27708008
YD180_YEASTYDL180Wgenetic
27708008
SWF1_YEASTSWF1genetic
27708008
ARO1_YEASTARO1genetic
27708008
NUM1_YEASTNUM1genetic
27708008
SAC3_YEASTSAC3genetic
27708008
PMP3_YEASTPMP3genetic
27708008
PAL1_YEASTPAL1genetic
27708008
RV167_YEASTRVS167genetic
27708008
UBP3_YEASTUBP3genetic
27708008
FTHC_YEASTFAU1genetic
27708008
RIM15_YEASTRIM15genetic
27708008
PIB2_YEASTPIB2genetic
27708008
ATC1_YEASTPMR1genetic
27708008
HTD2_YEASTHTD2genetic
27708008
YIW2_YEASTYIR042Cgenetic
27708008
VPS53_YEASTVPS53genetic
27708008
LPLA_YEASTAIM22genetic
27708008
3HAO_YEASTBNA1genetic
27708008
IF5A2_YEASTANB1genetic
27708008
XPOT_YEASTLOS1genetic
27708008
UBI4P_YEASTUBI4genetic
27708008
FPS1_YEASTFPS1genetic
27708008
ARP6_YEASTARP6genetic
27708008
CSF1_YEASTCSF1genetic
27708008
AVL9_YEASTAVL9genetic
27708008
LIPB_YEASTLIP2genetic
27708008
VAC14_YEASTVAC14genetic
27708008
ADE_YEASTAAH1genetic
27708008
PHO80_YEASTPHO80genetic
27708008
KPR5_YEASTPRS5genetic
27708008
INO4_YEASTINO4genetic
27708008
BUB3_YEASTBUB3genetic
27708008
SERC_YEASTSER1genetic
27708008
UBA3_YEASTUBA3genetic
27708008
TKT1_YEASTTKL1genetic
27708008
COG3_YEASTCOG3genetic
29674565
YPT6_YEASTYPT6genetic
29674565
SCS7_YEASTSCS7genetic
29674565
KPC1_YEASTPKC1genetic
29674565
ALG14_YEASTALG14genetic
29674565
ARL1_YEASTARL1genetic
29674565
DPOD_YEASTPOL3genetic
29674565
DHAS_YEASTHOM2genetic
29674565
TCPA_YEASTTCP1genetic
29674565
TFB1_YEASTTFB1genetic
29674565
FCF1_YEASTFCF1genetic
29674565
ESC2_YEASTESC2genetic
29674565
VPS72_YEASTVPS72genetic
29674565
AK_YEASTHOM3genetic
29674565
CEM1_YEASTCEM1genetic
29674565
UBP3_YEASTUBP3genetic
29674565
SEC4_YEASTSEC4genetic
29674565
HUR1_YEASTHUR1genetic
29674565
HTD2_YEASTHTD2genetic
29674565
ARP1_YEASTARP1genetic
29674565
STB5_YEASTSTB5genetic
29674565
LPLA_YEASTAIM22genetic
29674565
PRS7_YEASTRPT1genetic
29674565
NOC3_YEASTNOC3genetic
29674565
ELP1_YEASTIKI3genetic
29674565
TAF11_YEASTTAF11genetic
29674565
VPS71_YEASTVPS71genetic
29674565
UTP15_YEASTUTP15genetic
29674565
DYN3_YEASTDYN3genetic
29674565
RFC4_YEASTRFC4genetic
29674565
VPS5_YEASTVPS5genetic
29674565
GYP1_YEASTGYP1genetic
29674565
SFL1_YEASTSFL1genetic
29674565
LIPA_YEASTLIP5genetic
29674565
DYR_YEASTDFR1genetic
29674565
TBF1_YEASTTBF1genetic
29674565
BRR1_YEASTBRR1genetic
29674565
KAR3_YEASTKAR3genetic
29674565
SWC5_YEASTSWC5genetic
29674565
OCA5_YEASTOCA5genetic
29674565
ICE2_YEASTICE2genetic
29674565
MOG1_YEASTMOG1genetic
29674565
VRP1_YEASTVRP1genetic
29674565
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of OCA4_YEAST

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis.";
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
Mol. Cell. Proteomics 7:1389-1396(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-87; SER-91; THR-92;SER-94; SER-290 AND SER-291, AND MASS SPECTROMETRY.
"Proteome-wide identification of in vivo targets of DNA damagecheckpoint kinases.";
Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H.;
Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-290 AND SER-291, ANDMASS SPECTROMETRY.
"Analysis of phosphorylation sites on proteins from Saccharomycescerevisiae by electron transfer dissociation (ETD) massspectrometry.";
Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L.,Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F.;
Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-291, AND MASSSPECTROMETRY.

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