| UniProt ID | DNM1_YEAST | |
|---|---|---|
| UniProt AC | P54861 | |
| Protein Name | Dynamin-related protein DNM1 | |
| Gene Name | DNM1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 757 | |
| Subcellular Localization |
Mitochondrion outer membrane Peripheral membrane protein Cytoplasmic side . Cytoplasm, localizes to the cytoplasmic outer membrane of mitochondria. |
|
| Protein Description | Microtubule-associated force-producing protein that participates mitochondrial fission. Fission of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. Functions antagonistically with FZO1.. | |
| Protein Sequence | MASLEDLIPTVNKLQDVMYDSGIDTLDLPILAVVGSQSSGKSSILETLVGRDFLPRGTGIVTRRPLVLQLNNISPNSPLIEEDDNSVNPHDEVTKISGFEAGTKPLEYRGKERNHADEWGEFLHIPGKRFYDFDDIKREIENETARIAGKDKGISKIPINLKVFSPHVLNLTLVDLPGITKVPIGEQPPDIEKQIKNLILDYIATPNCLILAVSPANVDLVNSESLKLAREVDPQGKRTIGVITKLDLMDSGTNALDILSGKMYPLKLGFVGVVNRSQQDIQLNKTVEESLDKEEDYFRKHPVYRTISTKCGTRYLAKLLNQTLLSHIRDKLPDIKTKLNTLISQTEQELARYGGVGATTNESRASLVLQLMNKFSTNFISSIDGTSSDINTKELCGGARIYYIYNNVFGNSLKSIDPTSNLSVLDVRTAIRNSTGPRPTLFVPELAFDLLVKPQIKLLLEPSQRCVELVYEELMKICHKCGSAELARYPKLKSMLIEVISELLRERLQPTRSYVESLIDIHRAYINTNHPNFLSATEAMDDIMKTRRKRNQELLKSKLSQQENGQTNGINGTSSISSNIDQDSAKNSDYDDDGIDAESKQTKDKFLNYFFGKDKKGQPVFDASDKKRSIAGDGNIEDFRNLQISDFSLGDIDDLENAEPPLTEREELECELIKRLIVSYFDIIREMIEDQVPKAVMCLLVNYCKDSVQNRLVTKLYKETLFEELLVEDQTLAQDRELCVKSLGVYKKAATLISNIL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 74 | Phosphorylation | VLQLNNISPNSPLIE EEEECCCCCCCCCCC | 21.83 | 23607784 | |
| 77 | Phosphorylation | LNNISPNSPLIEEDD ECCCCCCCCCCCCCC | 25.19 | 29136822 | |
| 86 | Phosphorylation | LIEEDDNSVNPHDEV CCCCCCCCCCCCCHH | 30.20 | 23607784 | |
| 94 | Phosphorylation | VNPHDEVTKISGFEA CCCCCHHHHHCCCCC | 22.17 | 23607784 | |
| 131 | Phosphorylation | HIPGKRFYDFDDIKR CCCCCCCCCHHHHHH | 21.52 | 21551504 | |
| 152 | Acetylation | ARIAGKDKGISKIPI HHHCCCCCCCCCCCC | 62.72 | 25381059 | |
| 193 | Acetylation | EQPPDIEKQIKNLIL CCCCCHHHHHHHHHH | 58.62 | 24489116 | |
| 277 | Phosphorylation | FVGVVNRSQQDIQLN EEEEECCCHHHHHCC | 27.30 | 28889911 | |
| 293 | Acetylation | TVEESLDKEEDYFRK HHHHHCCCHHHHHHH | 69.19 | 24489116 | |
| 313 | Phosphorylation | TISTKCGTRYLAKLL HHCCHHCHHHHHHHH | 26.13 | 25533186 | |
| 318 | Acetylation | CGTRYLAKLLNQTLL HCHHHHHHHHHHHHH | 51.41 | 24489116 | |
| 423 | Phosphorylation | IDPTSNLSVLDVRTA CCCCCCCEEEHHHHH | 25.53 | 27214570 | |
| 494 | Phosphorylation | ARYPKLKSMLIEVIS HHCHHHHHHHHHHHH | 29.29 | 27017623 | |
| 501 | Phosphorylation | SMLIEVISELLRERL HHHHHHHHHHHHHHH | 27.63 | 27017623 | |
| 567 | Phosphorylation | SQQENGQTNGINGTS HHCCCCCCCCCCCCC | 36.49 | 19779198 | |
| 573 | Phosphorylation | QTNGINGTSSISSNI CCCCCCCCCCCCCCC | 18.14 | 21551504 | |
| 574 | Phosphorylation | TNGINGTSSISSNID CCCCCCCCCCCCCCC | 27.37 | 21551504 | |
| 575 | Phosphorylation | NGINGTSSISSNIDQ CCCCCCCCCCCCCCC | 26.74 | 20377248 | |
| 577 | Phosphorylation | INGTSSISSNIDQDS CCCCCCCCCCCCCCH | 21.20 | 23749301 | |
| 578 | Phosphorylation | NGTSSISSNIDQDSA CCCCCCCCCCCCCHH | 35.81 | 20377248 | |
| 584 | Phosphorylation | SSNIDQDSAKNSDYD CCCCCCCHHHCCCCC | 35.19 | 21440633 | |
| 588 | Phosphorylation | DQDSAKNSDYDDDGI CCCHHHCCCCCCCCC | 36.52 | 29136822 | |
| 590 | Phosphorylation | DSAKNSDYDDDGIDA CHHHCCCCCCCCCCC | 22.54 | 29136822 | |
| 605 | Acetylation | ESKQTKDKFLNYFFG CHHHHHHHHHHHHCC | 53.99 | 24489116 | |
| 629 | Phosphorylation | DASDKKRSIAGDGNI CCCCCCCCCCCCCCH | 26.18 | 11553714 | |
| 645 | Phosphorylation | DFRNLQISDFSLGDI HHHCCCCCCCCCCCH | 21.46 | 30377154 | |
| 648 | Phosphorylation | NLQISDFSLGDIDDL CCCCCCCCCCCHHHH | 36.11 | 30377154 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DNM1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DNM1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DNM1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-629, AND MASSSPECTROMETRY. | |
