MGR3_YEAST - dbPTM
MGR3_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MGR3_YEAST
UniProt AC Q04472
Protein Name Mitochondrial inner membrane i-AAA protease supercomplex subunit MGR3
Gene Name MGR3
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 501
Subcellular Localization Mitochondrion inner membrane
Single-pass membrane protein .
Protein Description Component of the mitochondrial inner membrane i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins. Together with MGR1, functions in an adapter complex that targets substrates to the i-AAA protease for degradation. Required for growth of cells lacking the mitochondrial genome..
Protein Sequence MLLQGMRLSQRLHKRHLFASKILTWTTNPAHIRHLHDIRPPASNFNTQESAPIPESPANSPTRPQMAPKPNLKKKNRSLMYSIIGVSIVGLYFWFKSNSRKQKLPLSAQKVWKEAIWQESDKMDFNYKEALRRYIEALDECDRSHVDLLSDDYTRIELKIAEMYEKLNMLEEAQNLYQELLSRFFEALNVPGKVDESERGEVLRKDLRILIKSLEINKDIESGKRKLLQHLLLAQEEILSKSPELKEFFENRKKKLSMVKDINRDPNDDFKTFVSEENIKFDEQGYMILDLEKNSSAWEPFKEEFFTARDLYTAYCLSSKDIAAALSCKITSVEWMVMADMPPGQILLSQANLGSLFYLQAEKLEADLNQLEQKKSKESNQELDMGTYIKAVRFVRKNRDLCLERAQKCYDSVIAFAKRNRKIRFHVKDQLDPSIAQSIALSTYGMGVLSLHEGVLAKAEKLFKDSITMAKETEFNELLAEAEKELEKTTVLKAAKKEGLN
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
327PhosphorylationKDIAAALSCKITSVE
HHHHHHHCCCEEEEE		14.5028747907
331PhosphorylationAALSCKITSVEWMVM
HHHCCCEEEEEEEEE		16.5329136822
332PhosphorylationALSCKITSVEWMVMA
HHCCCEEEEEEEEEC		22.8528747907
349PhosphorylationPPGQILLSQANLGSL
CCCCEEEEECCCCHH		24.6528747907
355PhosphorylationLSQANLGSLFYLQAE
EEECCCCHHHHHHHH		20.6228747907
358PhosphorylationANLGSLFYLQAEKLE
CCCCHHHHHHHHHHH		11.8228747907
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MGR3_YEAST !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MGR3_YEAST !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MGR3_YEAST !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YME1_YEASTYME1physical
18843051
MGR1_YEASTMGR1physical
18843051
AFG3_YEASTAFG3physical
18843051
SCO2_YEASTSCO2genetic
20093466
C1TM_YEASTMIS1genetic
20093466
CCZ1_YEASTCCZ1genetic
20093466
RMD9L_YEASTYBR238Cgenetic
20093466
SNF5_YEASTSNF5genetic
20093466
MGR1_YEASTMGR1genetic
20093466
HSP30_YEASTHSP30genetic
20093466
SNT1_YEASTSNT1genetic
20093466
CRD1_YEASTCRD1genetic
20093466
SWR1_YEASTSWR1genetic
20093466
MIC19_YEASTMIC19genetic
20093466
MED20_YEASTSRB2genetic
20093466
FYV4_YEASTFYV4genetic
20093466
FIS1_YEASTFIS1genetic
20093466
PIR5_YEASTYJL160Cgenetic
20093466
IML2_YEASTIML2genetic
20093466
GYP6_YEASTGYP6genetic
20093466
YJ90_YEASTYJR120Wgenetic
20093466
DCOR_YEASTSPE1genetic
20093466
SA190_YEASTSAP190genetic
20093466
SET3_YEASTSET3genetic
20093466
OMA1_YEASTOMA1genetic
20093466
YK104_YEASTYKR104Wgenetic
20093466
DNM1_YEASTDNM1genetic
20093466
YL050_YEASTYLR050Cgenetic
20093466
PFD6_YEASTYKE2genetic
20093466
CDC73_YEASTCDC73genetic
20093466
COX7_YEASTCOX7genetic
20093466
NGL2_YEASTNGL2genetic
20093466
YME2_YEASTYME2genetic
20093466
RCM1_YEASTRCM1genetic
20093466
CYP8_YEASTCPR8genetic
20093466
IRA2_YEASTIRA2genetic
20093466
DGK1_YEASTDGK1genetic
20093466
MGR2_YEASTMGR2genetic
20093466
TAZ1_YEASTTAZ1genetic
20093466
OXA1_YEASTOXA1genetic
19307606
GEM1_YEASTGEM1genetic
21987634
FZO1_YEASTFZO1genetic
21987634
CRD1_YEASTCRD1genetic
21987634
DOP1_YEASTDOP1genetic
21987634
RPB7_YEASTRPB7genetic
21987634
AFG3_YEASTAFG3genetic
21987634
ISC1_YEASTISC1genetic
21987634
MDJ1_YEASTMDJ1genetic
21987634
RPOM_YEASTRPO41genetic
21987634
AAKG_YEASTSNF4genetic
21987634
PCP1_YEASTPCP1genetic
21987634
PHB1_YEASTPHB1genetic
21987634
PHB2_YEASTPHB2genetic
21987634
GEP4_YEASTGEP4genetic
21987634
FIS1_YEASTFIS1genetic
21987634
PT130_YEASTPET130genetic
21987634
MG101_YEASTMGM101genetic
21987634
PMIP_YEASTOCT1genetic
21987634
MIC60_YEASTMIC60genetic
21987634
LAS1_YEASTLAS1genetic
21987634
DNM1_YEASTDNM1genetic
21987634
GEP5_YEASTGEP5genetic
21987634
PGA3_YEASTPGA3genetic
21987634
SAM37_YEASTSAM37genetic
21987634
IPYR2_YEASTPPA2genetic
21987634
GATA_YEASTHER2genetic
21987634
YME2_YEASTYME2genetic
21987634
IF2M_YEASTIFM1genetic
21987634
IRA2_YEASTIRA2genetic
21987634
INO4_YEASTINO4genetic
21987634
MDM32_YEASTMDM32genetic
21987634
GEP3_YEASTGEP3genetic
21987634
DPOG_YEASTMIP1genetic
21987634
MGR2_YEASTMGR2genetic
21987634
FMP30_YEASTFMP30genetic
21987634
SYFM_YEASTMSF1genetic
21987634
C1TM_YEASTMIS1genetic
27708008
NGL2_YEASTNGL2genetic
27708008
GGPPS_YEASTBTS1genetic
27708008
VPS4_YEASTVPS4genetic
27708008
CCZ1_YEASTCCZ1genetic
27708008
SNT1_YEASTSNT1genetic
27708008
MTU1_YEASTSLM3genetic
27708008
CRD1_YEASTCRD1genetic
27708008
INO2_YEASTINO2genetic
27708008
UME6_YEASTUME6genetic
27708008
ARO8_YEASTARO8genetic
27708008
PHB1_YEASTPHB1genetic
27708008
FIS1_YEASTFIS1genetic
27708008
MIC60_YEASTMIC60genetic
27708008
SA190_YEASTSAP190genetic
27708008
SET3_YEASTSET3genetic
27708008
OMA1_YEASTOMA1genetic
27708008
DNM1_YEASTDNM1genetic
27708008
YL407_YEASTYLR407Wgenetic
27708008
CDC73_YEASTCDC73genetic
27708008
MGR2_YEASTMGR2genetic
27708008
TAZ1_YEASTTAZ1genetic
27708008
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MGR3_YEAST

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Related Literatures of Post-Translational Modification

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