NGL2_YEAST - dbPTM
NGL2_YEAST - PTM Information in dbPTM
Basic Information of Protein
UniProt ID NGL2_YEAST
UniProt AC Q03264
Protein Name RNA exonuclease NGL2
Gene Name NGL2
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length 515
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Involved in pre-rRNA processing. Required for the final stage of 3'-end maturation of 5.8S rRNA at site E..
Protein Sequence MTQDKEVKVVAPDVAPDQEVEINKSVKDAKHQTNDDSLLQHKKKGKKGKKSKPIVTPEHIAKVRAEREVMRKAKRDAMLAQGVDPDCPPELHFIRRPFLSLHEAEPVTGFRFKLMTYNCLAQALIRRKLFPDSGDALKWYRRSKVLLNEFKYYNSDVICLQEIDHIQFQSFWKDEFSKLGYDGQYYRNATKNHGVAIMWRRELFHQVDKMLIDYDKESSESISTRTTTNNVGLVLALKFSEKVLSNLGKKSSKKCGILIGTTHLFWHPFGTYERTRQCYIVLKKMKEFMHRVNVLQNENDGDLSHWFPFFCGDFNSQPFDTPYLSMTSKPVHYRNRAKTVIGCSTSYKFSKVRDGEEGADDEEGGNIEKYGKDQPESPVPEKFHANEEQSELVDKMAQLHNSLDMRAISLYSVGYKNVHPENAGLDNDRGEPEISNWANTWRGLLDYLFYVKKWDPQSNCQEVETLGDFEKENKVKCRGFLRMPPGNEMTKHGQPHVGEYASDHLSMVCDLELQL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
24AcetylationDQEVEINKSVKDAKH
CCEEEECHHHCHHCC
63.3924489116
25PhosphorylationQEVEINKSVKDAKHQ
CEEEECHHHCHHCCC
29.8824961812
42AcetylationDDSLLQHKKKGKKGK
CHHHHHHHHCCCCCC
43.1325381059
56PhosphorylationKKSKPIVTPEHIAKV
CCCCCCCCHHHHHHH
24.5521440633
209AcetylationELFHQVDKMLIDYDK
HHHHHHHHHHCCCCH
36.4324489116
245PhosphorylationKFSEKVLSNLGKKSS
HHHHHHHHHCCCCHH
32.7528889911
339PhosphorylationHYRNRAKTVIGCSTS
CCCCCCCEEEEECCC
19.1727017623
344PhosphorylationAKTVIGCSTSYKFSK
CCEEEEECCCCEEEE
18.3830377154
347PhosphorylationVIGCSTSYKFSKVRD
EEEECCCCEEEECCC
19.0127017623
348AcetylationIGCSTSYKFSKVRDG
EEECCCCEEEECCCC
42.8224489116
350PhosphorylationCSTSYKFSKVRDGEE
ECCCCEEEECCCCCC
26.5330377154
377PhosphorylationYGKDQPESPVPEKFH
CCCCCCCCCCCCCCC
37.5722369663
382AcetylationPESPVPEKFHANEEQ
CCCCCCCCCCCCHHH
36.0624489116
409PhosphorylationSLDMRAISLYSVGYK
HHHHHHHEEHHCCCC
21.9222369663
411PhosphorylationDMRAISLYSVGYKNV
HHHHHEEHHCCCCCC
8.4322369663
412PhosphorylationMRAISLYSVGYKNVH
HHHHEEHHCCCCCCC
17.8522369663
415PhosphorylationISLYSVGYKNVHPEN
HEEHHCCCCCCCHHH
9.3822369663

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of NGL2_YEAST !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of NGL2_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of NGL2_YEAST !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HPR1_YEASTHPR1genetic
19061648
ARC1_YEASTARC1genetic
19061648
SYMM_YEASTMSM1genetic
19061648
CBT1_YEASTCBT1genetic
19061648
LTV1_YEASTLTV1genetic
19061648
IF2M_YEASTIFM1genetic
19061648
EFTU_YEASTTUF1genetic
19061648
SYKM_YEASTMSK1genetic
19061648
SUV3_YEASTSUV3genetic
19061648
SYFM_YEASTMSF1genetic
19061648
NOP8_YEASTNOP8genetic
19061648
SYDM_YEASTMSD1genetic
19061648
SSB1_YEASTSSB1physical
19536198
SLX5_YEASTSLX5genetic
27708008
RL19A_YEASTRPL19Bgenetic
27708008
RL19B_YEASTRPL19Bgenetic
27708008
URA7_YEASTURA7genetic
27708008
MBA1_YEASTMBA1genetic
27708008
ODPB_YEASTPDB1genetic
27708008
CHK1_YEASTCHK1genetic
27708008
NHP10_YEASTNHP10genetic
27708008
RPN4_YEASTRPN4genetic
27708008
MTU1_YEASTSLM3genetic
27708008
RLA1_YEASTRPP1Agenetic
27708008
CYK3_YEASTCYK3genetic
27708008
S2538_YEASTYDL119Cgenetic
27708008
RM01_YEASTMRPL1genetic
27708008
ARO1_YEASTARO1genetic
27708008
OMS1_YEASTOMS1genetic
27708008
BCS1_YEASTBCS1genetic
27708008
ODPA_YEASTPDA1genetic
27708008
DLDH_YEASTLPD1genetic
27708008
MMS2_YEASTMMS2genetic
27708008
MDM34_YEASTMDM34genetic
27708008
CHO2_YEASTCHO2genetic
27708008
COX23_YEASTCOX23genetic
27708008
PIR5_YEASTYJL160Cgenetic
27708008
COXM1_YEASTCMC1genetic
27708008
RM49_YEASTMRP49genetic
27708008
RS21A_YEASTRPS21Agenetic
27708008
ENV10_YEASTENV10genetic
27708008
YL225_YEASTYLR225Cgenetic
27708008
MMS22_YEASTMMS22genetic
27708008
COX8_YEASTCOX8genetic
27708008
TSR2_YEASTTSR2genetic
27708008
SST2_YEASTSST2genetic
27708008
RCF1_YEASTRCF1genetic
27708008
MAC1_YEASTMAC1genetic
27708008
MSS1_YEASTMSS1genetic
27708008
GBLP_YEASTASC1genetic
27708008
COX5A_YEASTCOX5Agenetic
27708008
ODP2_YEASTLAT1genetic
27708008
SWS2_YEASTSWS2genetic
27708008
YO08A_YEASTYOR008C-Agenetic
27708008
CYC2_YEASTCYC2genetic
27708008
CY1_YEASTCYT1genetic
27708008
FYV12_YEASTFYV12genetic
27708008
LIPA_YEASTLIP5genetic
27708008
MNE1_YEASTMNE1genetic
27708008
HSP7F_YEASTSSE1genetic
27708008

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of NGL2_YEAST

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Related Literatures of Post-Translational Modification

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