UniProt ID | NGL2_YEAST | |
---|---|---|
UniProt AC | Q03264 | |
Protein Name | RNA exonuclease NGL2 | |
Gene Name | NGL2 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 515 | |
Subcellular Localization | Cytoplasm . Nucleus . | |
Protein Description | Involved in pre-rRNA processing. Required for the final stage of 3'-end maturation of 5.8S rRNA at site E.. | |
Protein Sequence | MTQDKEVKVVAPDVAPDQEVEINKSVKDAKHQTNDDSLLQHKKKGKKGKKSKPIVTPEHIAKVRAEREVMRKAKRDAMLAQGVDPDCPPELHFIRRPFLSLHEAEPVTGFRFKLMTYNCLAQALIRRKLFPDSGDALKWYRRSKVLLNEFKYYNSDVICLQEIDHIQFQSFWKDEFSKLGYDGQYYRNATKNHGVAIMWRRELFHQVDKMLIDYDKESSESISTRTTTNNVGLVLALKFSEKVLSNLGKKSSKKCGILIGTTHLFWHPFGTYERTRQCYIVLKKMKEFMHRVNVLQNENDGDLSHWFPFFCGDFNSQPFDTPYLSMTSKPVHYRNRAKTVIGCSTSYKFSKVRDGEEGADDEEGGNIEKYGKDQPESPVPEKFHANEEQSELVDKMAQLHNSLDMRAISLYSVGYKNVHPENAGLDNDRGEPEISNWANTWRGLLDYLFYVKKWDPQSNCQEVETLGDFEKENKVKCRGFLRMPPGNEMTKHGQPHVGEYASDHLSMVCDLELQL | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
24 | Acetylation | DQEVEINKSVKDAKH CCEEEECHHHCHHCC | 63.39 | 24489116 | |
25 | Phosphorylation | QEVEINKSVKDAKHQ CEEEECHHHCHHCCC | 29.88 | 24961812 | |
42 | Acetylation | DDSLLQHKKKGKKGK CHHHHHHHHCCCCCC | 43.13 | 25381059 | |
56 | Phosphorylation | KKSKPIVTPEHIAKV CCCCCCCCHHHHHHH | 24.55 | 21440633 | |
209 | Acetylation | ELFHQVDKMLIDYDK HHHHHHHHHHCCCCH | 36.43 | 24489116 | |
245 | Phosphorylation | KFSEKVLSNLGKKSS HHHHHHHHHCCCCHH | 32.75 | 28889911 | |
339 | Phosphorylation | HYRNRAKTVIGCSTS CCCCCCCEEEEECCC | 19.17 | 27017623 | |
344 | Phosphorylation | AKTVIGCSTSYKFSK CCEEEEECCCCEEEE | 18.38 | 30377154 | |
347 | Phosphorylation | VIGCSTSYKFSKVRD EEEECCCCEEEECCC | 19.01 | 27017623 | |
348 | Acetylation | IGCSTSYKFSKVRDG EEECCCCEEEECCCC | 42.82 | 24489116 | |
350 | Phosphorylation | CSTSYKFSKVRDGEE ECCCCEEEECCCCCC | 26.53 | 30377154 | |
377 | Phosphorylation | YGKDQPESPVPEKFH CCCCCCCCCCCCCCC | 37.57 | 22369663 | |
382 | Acetylation | PESPVPEKFHANEEQ CCCCCCCCCCCCHHH | 36.06 | 24489116 | |
409 | Phosphorylation | SLDMRAISLYSVGYK HHHHHHHEEHHCCCC | 21.92 | 22369663 | |
411 | Phosphorylation | DMRAISLYSVGYKNV HHHHHEEHHCCCCCC | 8.43 | 22369663 | |
412 | Phosphorylation | MRAISLYSVGYKNVH HHHHEEHHCCCCCCC | 17.85 | 22369663 | |
415 | Phosphorylation | ISLYSVGYKNVHPEN HEEHHCCCCCCCHHH | 9.38 | 22369663 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of NGL2_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of NGL2_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of NGL2_YEAST !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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