dbPTM

YL225_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YL225_YEAST
UniProt AC	Q05948
Protein Name	Uncharacterized SVF1-like protein YLR225C
Gene Name	YLR225C
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	407
Subcellular Localization	Cytoplasm .
Protein Description
Protein Sequence	MAVAIKKEKTKFAPVKEVLSEKDHANYTKFQDTSKLEWFCRTSNHKKFKSHSLLKAVRNPTETRIETQTLYFTDLTNGKCGLIQLLYSSVMGGIYKGFQLNFKIFKASSEENSEEDIDIWESFKIDNIKDFDTLKVESDNVTFHFVPLENSSSSGFAQLLIKIDIPKGSTSCLLKDLKVDITVNLQEGFIINPDGSNYYLDKSISLEELAKRDSSSTSRKMIRHVFVPRGFCNGTISYKKNDKPVKLDLKDTPMLYLDAVQGLIPNKAASKWNFLCFNGEKRSMMCIEFTTTKEYGSTTVTIWAVSDKDKILEVGSSVNDHAVKFPSTKEDKQNGWKYPTSISFPRGFEESNLRLVNRYDIMSELPAFIRSIAENLANMKPFIYQFCQKSKFDDDEGVSIIESTFIN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Ubiquitination	VKEVLSEKDHANYTK HHHHCCCCCCCCCCC	51.98	23749301
29	Acetylation	KDHANYTKFQDTSKL CCCCCCCCCCCCCCC	30.57	24489116
55	Acetylation	FKSHSLLKAVRNPTE CCCHHHHHHHCCCCC	50.56	25381059
108	Phosphorylation	NFKIFKASSEENSEE EEEEEECCCCCCCHH	38.58	28889911
109	Phosphorylation	FKIFKASSEENSEED EEEEECCCCCCCHHH	54.51	28889911
167	Acetylation	LIKIDIPKGSTSCLL EEEEECCCCCCEEEE	66.87	25381059
175	Acetylation	GSTSCLLKDLKVDIT CCCEEEECCCEEEEE	48.33	22865919
310	Ubiquitination	WAVSDKDKILEVGSS EEECCHHCEEEECCC	55.73	24961812
328	Phosphorylation	HAVKFPSTKEDKQNG CCCCCCCCHHHHCCC	38.40	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YL225_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YL225_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YL225_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DAP2_YEAST	DAP2	genetic	27708008
MAD3_YEAST	MAD3	genetic	27708008
INO1_YEAST	INO1	genetic	27708008
FAR8_YEAST	FAR8	genetic	27708008
YAP7_YEAST	YAP7	genetic	27708008
DSD1_YEAST	DSD1	genetic	27708008
KEX1_YEAST	KEX1	genetic	27708008
MVB12_YEAST	MVB12	genetic	27708008
KEL2_YEAST	KEL2	genetic	27708008
TBP7_YEAST	YTA7	genetic	27708008
DUR3_YEAST	DUR3	genetic	27708008
YHE2_YEAST	YHL042W	genetic	27708008
PPME1_YEAST	PPE1	genetic	27708008
HXT5_YEAST	HXT5	genetic	27708008
YHS7_YEAST	YHR127W	genetic	27708008
AIM46_YEAST	AIM46	genetic	27708008
YH10_YEAST	YHR210C	genetic	27708008
YIA6_YEAST	YIA6	genetic	27708008
YIC9_YEAST	YIL029C	genetic	27708008
THIK_YEAST	POT1	genetic	27708008
YUR1_YEAST	YUR1	genetic	27708008
RCY1_YEAST	RCY1	genetic	27708008
RSF2_YEAST	RSF2	genetic	27708008
POC2_YEAST	ADD66	genetic	27708008
SRL3_YEAST	SRL3	genetic	27708008
YOX1_YEAST	YOX1	genetic	27708008
FKBP3_YEAST	FPR3	genetic	27708008
IDHH_YEAST	IDP3	genetic	27708008
TCB2_YEAST	TCB2	genetic	27708008
KC12_YEAST	YCK2	genetic	27708008
MNT4_YEAST	MNT4	genetic	27708008
COS10_YEAST	COS10	genetic	27708008
PHO80_YEAST	PHO80	genetic	27708008
YO036_YEAST	YOL036W	genetic	27708008
MET22_YEAST	MET22	genetic	27708008
MPC70_YEAST	SPO21	genetic	27708008
2A5D_YEAST	RTS1	genetic	27708008
SERC_YEAST	SER1	genetic	27708008
FSF1_YEAST	FSF1	genetic	27708008
POC4_YEAST	POC4	genetic	27708008
SRO7_YEAST	SRO7	genetic	27708008
MDM36_YEAST	MDM36	genetic	27708008
AXL1_YEAST	AXL1	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YL225_YEAST

Related Literatures of Post-Translational Modification