dbPTM

YHS7_YEAST - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YHS7_YEAST
UniProt AC	P38833
Protein Name	Uncharacterized protein YHR127W
Gene Name	YHR127W
Organism	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
Sequence Length	243
Subcellular Localization
Protein Description
Protein Sequence	MARNRTTSKKNVQSKRLIDRVVPMDKIKKVGVAKKKTVEHTKEGFSVVNGKLVSSNDVGVLLREAQGAIDKRTNVSQRNRKKGIKNNRPHKDINSSPDWGNAHRGTDWQSEKANGMNRAKNSRNFTTNIKLQRQHFGEEIQGGSQLVISTNSDASDKLLMLFNLTLGVNQENLKNVLENISQVQIAQIRVRDLPSGSATAKVRLAYPTTQSLEKVRKLFHGALVDGRRIQVVIASDESSHLSY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
8	Phosphorylation	MARNRTTSKKNVQSK CCCCCCCCCHHHHHH	40.81	28889911
54	Phosphorylation	VVNGKLVSSNDVGVL EECCEEEECCCHHHH	33.58	21440633
71	Acetylation	EAQGAIDKRTNVSQR HHHHHHHHCCCHHHH	55.82	25381059
85	Acetylation	RNRKKGIKNNRPHKD HHHHHCCCCCCCCCC	57.76	25381059
91	Acetylation	IKNNRPHKDINSSPD CCCCCCCCCCCCCCC	64.09	25381059
95	Phosphorylation	RPHKDINSSPDWGNA CCCCCCCCCCCCCCC	43.51	22369663
96	Phosphorylation	PHKDINSSPDWGNAH CCCCCCCCCCCCCCC	23.53	22369663
106	Phosphorylation	WGNAHRGTDWQSEKA CCCCCCCCCHHHHHH	33.74	19823750
110	Phosphorylation	HRGTDWQSEKANGMN CCCCCHHHHHHCCCC	36.49	19823750
122	Phosphorylation	GMNRAKNSRNFTTNI CCCCCCCCCCCCCCC	28.09	28889911
201	Ubiquitination	PSGSATAKVRLAYPT CCCCCCEEEEEECCC	24.43	22817900
235	Phosphorylation	RIQVVIASDESSHLS EEEEEEECCCCCCCC	30.68	30377154
242	Phosphorylation	SDESSHLSY------ CCCCCCCCC------	24.31	28889911
243	Phosphorylation	DESSHLSY------- CCCCCCCC-------	29.00	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YHS7_YEAST !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YHS7_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YHS7_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YRA1_YEAST	YRA1	physical	16554755
RRS1_YEAST	RRS1	physical	16554755
PRP40_YEAST	PRP40	physical	16554755
HSP71_YEAST	SSA1	physical	19536198
ORC2_YEAST	ORC2	genetic	27708008
CDC37_YEAST	CDC37	genetic	27708008
GPI8_YEAST	GPI8	genetic	27708008
GNA1_YEAST	GNA1	genetic	27708008
NU159_YEAST	NUP159	genetic	27708008
FIP1_YEAST	FIP1	genetic	27708008
BUR1_YEAST	SGV1	genetic	27708008
NSE4_YEAST	NSE4	genetic	27708008
RPB1_YEAST	RPO21	genetic	27708008
MAK21_YEAST	MAK21	genetic	27708008
RRP1_YEAST	RRP1	genetic	27708008
ERF3_YEAST	SUP35	genetic	27708008
COPB_YEAST	SEC26	genetic	27708008
RSC3_YEAST	RSC3	genetic	27708008
TFB1_YEAST	TFB1	genetic	27708008
MOB2_YEAST	MOB2	genetic	27708008
ACT_YEAST	ACT1	genetic	27708008
MCE1_YEAST	CEG1	genetic	27708008
TIP20_YEAST	TIP20	genetic	27708008
BRR6_YEAST	BRR6	genetic	27708008
NOP56_YEAST	NOP56	genetic	27708008
PGA3_YEAST	PGA3	genetic	27708008
DPOA_YEAST	POL1	genetic	27708008
PROF_YEAST	PFY1	genetic	27708008
RPB2_YEAST	RPB2	genetic	27708008
RPA1_YEAST	RPA190	genetic	27708008
TF2B_YEAST	SUA7	genetic	27708008

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YHS7_YEAST

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-54; SER-96; SER-242 ANDTYR-243, AND MASS SPECTROMETRY.	18407956 [Abstract]
"Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-96, AND MASSSPECTROMETRY.	17330950 [Abstract]