RRS1_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RRS1_YEAST
• UniProt AC: Q08746
• Protein Name: Regulator of ribosome biosynthesis
• Gene Name: RRS1
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 203
• Subcellular Localization: Nucleus .
• Protein Description: Required for ribosome biogenesis..
• Protein Sequence: MSAEDYKNLPVTVEKPIPVVYDLGNLAAFDSNVLDKNDLDSSNARREEKIKSLTRDNVQLLINQLLSLPMKTTTESVGGTGGQSSVMTLLQLPDPTTDLPREKPLPKAKAMTKWEKFAAKKGIKPKERAGKMIYDEASGEWVPKWGYKGANKKLDDQWLVEVDDKVKGTDNELIDPRTLNRAERKRLVKKNEKQQRRNMKNAL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
113	Acetylation	PKAKAMTKWEKFAAK CHHHHHHHHHHHHHH	40.03	24489116
116	Acetylation	KAMTKWEKFAAKKGI HHHHHHHHHHHHCCC	38.91	25381059
131	Acetylation	KPKERAGKMIYDEAS CHHHHCCCEEEECCC	22.57	24489116
144	Acetylation	ASGEWVPKWGYKGAN CCCCCCCCCCCCCCC	43.56	24489116
148	Acetylation	WVPKWGYKGANKKLD CCCCCCCCCCCCCCC	47.83	25381059
152	Acetylation	WGYKGANKKLDDQWL CCCCCCCCCCCCCEE	54.93	25381059
169	Phosphorylation	VDDKVKGTDNELIDP ECCCCCCCCCCCCCH	29.90	24961812

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RRS1_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RRS1_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RRS1_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RPF2_YEAST	RPF2	physical	12048200
EBP2_YEAST	EBP2	physical	12048200
EBP2_YEAST	EBP2	physical	10947841
RL11A_YEAST	RPL11A	physical	11893754
RL11B_YEAST	RPL11B	physical	11893754
RL3_YEAST	RPL3	physical	11893754
EBP2_YEAST	EBP2	physical	11893754
RL5_YEAST	RPL5	physical	16100378
RL11A_YEAST	RPL11A	physical	16100378
RL11B_YEAST	RPL11B	physical	16100378
RPF2_YEAST	RPF2	physical	17938242
RL5_YEAST	RPL5	physical	17938242
RL11A_YEAST	RPL11A	physical	17938242
RL11B_YEAST	RPL11B	physical	17938242
RLA0_YEAST	RPP0	physical	17938242
EBP2_YEAST	EBP2	physical	17938242
KCS1_YEAST	KCS1	genetic	19202276
LHP1_YEAST	LHP1	genetic	16581807
EBP2_YEAST	EBP2	physical	22319211
BRX1_YEAST	BRX1	physical	22319211
RLP7_YEAST	RLP7	physical	24129494
RIM11_YEAST	RIM11	physical	25035982
MRK1_YEAST	MRK1	physical	25035982
RPF2_YEAST	RPF2	physical	25877921
RPF2_YEAST	RPF2	physical	26122634
EBP2_YEAST	EBP2	physical	26122634
RPF2_YEAST	RPF2	physical	26159998
YCZ2_YEAST	YCR102C	genetic	27708008
BCK1_YEAST	BCK1	genetic	27708008
TFC6_YEAST	TFC6	genetic	27708008
CDC4_YEAST	CDC4	genetic	27708008
PRS8_YEAST	RPT6	genetic	27708008
RPF2_YEAST	RPF2	genetic	27708008
NOP2_YEAST	NOP2	genetic	27708008
PSB5_YEAST	PRE2	genetic	27708008
SGF29_YEAST	SGF29	genetic	27708008
RMD1_YEAST	RMD1	genetic	27708008
SAP1_YEAST	SAP1	genetic	27708008
UBP6_YEAST	UBP6	genetic	27708008
RMD8_YEAST	RMD8	genetic	27708008
RS25A_YEAST	RPS25A	genetic	27708008
VMA21_YEAST	VMA21	genetic	27708008
SMI1_YEAST	SMI1	genetic	27708008
REXO1_YEAST	RNH70	genetic	27708008
UBA4_YEAST	UBA4	genetic	27708008
SPO12_YEAST	SPO12	genetic	27708008
STB5_YEAST	STB5	genetic	27708008
AIR1_YEAST	AIR1	genetic	27708008
VPS53_YEAST	VPS53	genetic	27708008
PIR5_YEAST	YJL160C	genetic	27708008
UBR2_YEAST	UBR2	genetic	27708008
SIC1_YEAST	SIC1	genetic	27708008
GBLP_YEAST	ASC1	genetic	27708008
HDA1_YEAST	HDA1	genetic	27708008
EOS1_YEAST	EOS1	genetic	27708008
MSB4_YEAST	MSB4	genetic	27708008
YAP4_YEAST	CIN5	genetic	27708008
NACB1_YEAST	EGD1	genetic	27708008
SGF11_YEAST	SGF11	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.