| UniProt ID | RPA1_YEAST | |
|---|---|---|
| UniProt AC | P10964 | |
| Protein Name | DNA-directed RNA polymerase I subunit RPA190 | |
| Gene Name | RPA190 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 1664 | |
| Subcellular Localization | Nucleus, nucleolus . | |
| Protein Description | DNA-dependent RNA polymerases catalyze the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I (Pol I) which synthesizes ribosomal RNA precursors. Besides, RNA polymerase I has intrinsic RNA cleavage activity. RPA190 and RPA135 both contribute to the polymerase catalytic activity and together form the Pol I active center. In addition, subunit RPA12 contributes a catalytic zinc ribbon that is required for RNA cleavage by Pol I. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA190 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.. | |
| Protein Sequence | MDISKPVGSEITSVDFGILTAKEIRNLSAKQITNPTVLDNLGHPVSGGLYDLALGAFLRNLCSTCGLDEKFCPGHQGHIELPVPCYNPLFFNQLYIYLRASCLFCHHFRLKSVEVHRYACKLRLLQYGLIDESYKLDEITLGSLNSSMYTDDEAIEDNEDEMDGEGSKQSKDISSTLLNELKSKRSEYVDMAIAKALSDGRTTERGSFTATVNDERKKLVHEFHKKLLSRGKCDNCGMFSPKFRKDGFTKIFETALNEKQITNNRVKGFIRQDMIKKQKQAKKLDGSNEASANDEESFDVGRNPTTRPKTGSTYILSTEVKNILDTVFRKEQCVLQYVFHSRPNLSRKLVKADSFFMDVLVVPPTRFRLPSKLGEEVHENSQNQLLSKVLTTSLLIRDLNDDLSKLQKDKVSLEDRRVIFSRLMNAFVTIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGLFRKHMMGKRVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVINGPDKWPGATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYRHIKNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGAYNADFDGDEMNMHFPQNENARAEALNLANTDSQYLTPTSGSPVRGLIQDHISAGVWLTSKDSFFTREQYQQYIYGCIRPEDGHTTRSKIVTLPPTIFKPYPLWTGKQIITTVLLNVTPPDMPGINLISKNKIKNEYWGKGSLENEVLFKDGALLCGILDKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVTNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVPDGTMKKFPCNSMQAMALSGAKGSNVNVSQIMCLLGQQALEGRRVPVMVSGKTLPSFKPYETDAMAGGYVKGRFYSGIKPQEYYFHCMAGREGLIDTAVKTSRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDAIDITKESHMTQFEFCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKLFKSSDGVNEKKFRALMQLKYMRSLINPGEAVGIIASQSVGEPSTQMTLNTFHFAGHGAANVTLGIPRLREIVMTASAAIKTPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGTSNTAGGNAARSYVIHMRFFDNNEYSEEYDVSKEELQNVISNQFIHLLEAAIVKEIKKQKRTTGPDIGVAVPRLQTDVANSSSNSKRLEEDNDEEQSHKKTKQAVSYDEPDEDEIETMREAEKSSDEEGIDSDKESDSDSEDEDVDMNEQINKSIVEANNNMNKVQRDRQSAIISHHRFITKYNFDDESGKWCEFKLELAADTEKLLMVNIVEEICRKSIIRQIPHIDRCVHPEPENGKRVLVTEGVNFQAMWDQEAFIDVDGITSNDVAAVLKTYGVEAARNTIVNEINNVFSRYAISVSFRHLDLIADMMTRQGTYLAFNRQGMETSTSSFMKMSYETTCQFLTKAVLDNEREQLDSPSARIVVGKLNNVGTGSFDVLAKVPNAA | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 30 | Ubiquitination | EIRNLSAKQITNPTV HHHCCCCCCCCCCHH | 38.57 | 23749301 | |
| 70 | Ubiquitination | STCGLDEKFCPGHQG HHCCCCCCCCCCCCC | 52.51 | 17644757 | |
| 143 | Phosphorylation | LDEITLGSLNSSMYT CCEEEECCCCCCCCC | 27.73 | 30377154 | |
| 150 | Phosphorylation | SLNSSMYTDDEAIED CCCCCCCCCHHHHHC | 28.47 | 27214570 | |
| 171 | Ubiquitination | GEGSKQSKDISSTLL CCCCHHHHCHHHHHH | 57.49 | 17644757 | |
| 174 | Phosphorylation | SKQSKDISSTLLNEL CHHHHCHHHHHHHHH | 27.66 | 21440633 | |
| 175 | Phosphorylation | KQSKDISSTLLNELK HHHHCHHHHHHHHHH | 24.33 | 21440633 | |
| 182 | Acetylation | STLLNELKSKRSEYV HHHHHHHHHHHHHHH | 47.99 | 24489116 | |
| 182 | Ubiquitination | STLLNELKSKRSEYV HHHHHHHHHHHHHHH | 47.99 | 17644757 | |
| 184 | Ubiquitination | LLNELKSKRSEYVDM HHHHHHHHHHHHHHH | 59.35 | 17644757 | |
| 195 | Ubiquitination | YVDMAIAKALSDGRT HHHHHHHHHHHCCCC | 43.69 | 17644757 | |
| 198 | Phosphorylation | MAIAKALSDGRTTER HHHHHHHHCCCCCCC | 42.76 | 24961812 | |
| 202 | Phosphorylation | KALSDGRTTERGSFT HHHHCCCCCCCCEEE | 38.24 | 24961812 | |
| 203 | Phosphorylation | ALSDGRTTERGSFTA HHHCCCCCCCCEEEE | 23.48 | 24961812 | |
| 207 | Phosphorylation | GRTTERGSFTATVND CCCCCCCEEEEEECH | 26.16 | 19779198 | |
| 209 | Phosphorylation | TTERGSFTATVNDER CCCCCEEEEEECHHH | 24.10 | 24961812 | |
| 217 | Ubiquitination | ATVNDERKKLVHEFH EEECHHHHHHHHHHH | 48.70 | 17644757 | |
| 218 | Ubiquitination | TVNDERKKLVHEFHK EECHHHHHHHHHHHH | 63.06 | 17644757 | |
| 225 | Ubiquitination | KLVHEFHKKLLSRGK HHHHHHHHHHHHCCC | 50.89 | 17644757 | |
| 226 | Ubiquitination | LVHEFHKKLLSRGKC HHHHHHHHHHHCCCC | 46.20 | 17644757 | |
| 232 | Ubiquitination | KKLLSRGKCDNCGMF HHHHHCCCCCCCCCC | 36.99 | 17644757 | |
| 242 | Ubiquitination | NCGMFSPKFRKDGFT CCCCCCHHHCCCCCH | 57.51 | 17644757 | |
| 250 | Acetylation | FRKDGFTKIFETALN HCCCCCHHHHHHHCC | 43.04 | 24489116 | |
| 250 | Ubiquitination | FRKDGFTKIFETALN HCCCCCHHHHHHHCC | 43.04 | 17644757 | |
| 259 | Acetylation | FETALNEKQITNNRV HHHHCCHHHCCCCHH | 46.02 | 24489116 | |
| 259 | Ubiquitination | FETALNEKQITNNRV HHHHCCHHHCCCCHH | 46.02 | 24961812 | |
| 267 | Ubiquitination | QITNNRVKGFIRQDM HCCCCHHHHHHHHHH | 44.88 | 15699485 | |
| 276 | Ubiquitination | FIRQDMIKKQKQAKK HHHHHHHHHHHHHHC | 42.38 | 15699485 | |
| 277 | Ubiquitination | IRQDMIKKQKQAKKL HHHHHHHHHHHHHCC | 52.37 | 15699485 | |
| 282 | Ubiquitination | IKKQKQAKKLDGSNE HHHHHHHHCCCCCCC | 51.91 | 17644757 | |
| 283 | Ubiquitination | KKQKQAKKLDGSNEA HHHHHHHCCCCCCCC | 55.62 | 17644757 | |
| 287 | Phosphorylation | QAKKLDGSNEASAND HHHCCCCCCCCCCCC | 31.03 | 21440633 | |
| 291 | Phosphorylation | LDGSNEASANDEESF CCCCCCCCCCCHHHC | 22.79 | 24961812 | |
| 297 | Phosphorylation | ASANDEESFDVGRNP CCCCCHHHCCCCCCC | 25.38 | 21440633 | |
| 309 | Ubiquitination | RNPTTRPKTGSTYIL CCCCCCCCCCCEEEE | 63.33 | 17644757 | |
| 321 | Ubiquitination | YILSTEVKNILDTVF EEEEHHHHHHHHHHH | 31.85 | 17644757 | |
| 330 | Ubiquitination | ILDTVFRKEQCVLQY HHHHHHHHHHHHHHH | 40.44 | 17644757 | |
| 351 | Ubiquitination | NLSRKLVKADSFFMD CHHHHHHHCCCCEEE | 57.84 | 17644757 | |
| 354 | Phosphorylation | RKLVKADSFFMDVLV HHHHHCCCCEEEEEE | 25.83 | 28889911 | |
| 372 | Acetylation | TRFRLPSKLGEEVHE CCCCCCHHHCHHHHH | 59.58 | 24489116 | |
| 372 | Ubiquitination | TRFRLPSKLGEEVHE CCCCCCHHHCHHHHH | 59.58 | 17644757 | |
| 388 | Ubiquitination | SQNQLLSKVLTTSLL HHHHHHHHHHHHHHH | 41.03 | 17644757 | |
| 391 | Phosphorylation | QLLSKVLTTSLLIRD HHHHHHHHHHHHHHH | 19.82 | 21126336 | |
| 392 | Phosphorylation | LLSKVLTTSLLIRDL HHHHHHHHHHHHHHH | 17.14 | 21126336 | |
| 405 | Acetylation | DLNDDLSKLQKDKVS HHCHHHHHHHHCCCC | 63.33 | 24489116 | |
| 405 | Ubiquitination | DLNDDLSKLQKDKVS HHCHHHHHHHHCCCC | 63.33 | 17644757 | |
| 410 | Ubiquitination | LSKLQKDKVSLEDRR HHHHHHCCCCHHHHH | 40.53 | 23749301 | |
| 442 | Ubiquitination | NAFIDSTKAQGRTSG HHHHHHCCCCCCCCC | 42.54 | 15699485 | |
| 450 | Ubiquitination | AQGRTSGKVPIPGVK CCCCCCCCCCCCCHH | 44.60 | 17644757 | |
| 457 | Ubiquitination | KVPIPGVKQALEKKE CCCCCCHHHHHHHCC | 35.45 | 17644757 | |
| 474 | Ubiquitination | FRKHMMGKRVNYAAR HHHHHHHHHHHHHHH | 34.96 | 17644757 | |
| 504 | Ubiquitination | VPPVFAVKLTYPEPV CCCEEEEEECCCCCC | 31.51 | 17644757 | |
| 529 | Ubiquitination | AVINGPDKWPGATQI HHHCCCCCCCCCEEE | 59.42 | 17644757 | |
| 555 | Ubiquitination | GMSVEQRKALANQLL CCCHHHHHHHHHHHC | 47.66 | 17644757 | |
| 575 | Ubiquitination | VSTHTLNKKVYRHIK CCHHHCCHHHHHHHH | 46.88 | 17644757 | |
| 576 | Ubiquitination | STHTLNKKVYRHIKN CHHHCCHHHHHHHHC | 43.34 | 17644757 | |
| 582 | Ubiquitination | KKVYRHIKNRDVVLM HHHHHHHHCCCEEEE | 39.54 | 17644757 | |
| 597 | Ubiquitination | NRQPTLHKASMMGHK CCCCCCCHHHHCCCE | 45.31 | 17644757 | |
| 604 | Acetylation | KASMMGHKVRVLPNE HHHHCCCEEEECCCC | 26.46 | 25381059 | |
| 661 | Phosphorylation | DSQYLTPTSGSPVRG CCCCCCCCCCCCCHH | 40.25 | 30377154 | |
| 662 | Phosphorylation | SQYLTPTSGSPVRGL CCCCCCCCCCCCHHH | 38.18 | 30377154 | |
| 664 | Phosphorylation | YLTPTSGSPVRGLIQ CCCCCCCCCCHHHHH | 21.71 | 25752575 | |
| 683 | Ubiquitination | AGVWLTSKDSFFTRE CCCEECCCCCCCCHH | 52.75 | 17644757 | |
| 685 | Phosphorylation | VWLTSKDSFFTREQY CEECCCCCCCCHHHH | 26.46 | 28889911 | |
| 711 | Ubiquitination | DGHTTRSKIVTLPPT CCCCCCCCEEECCCC | 37.59 | 17644757 | |
| 721 | Acetylation | TLPPTIFKPYPLWTG ECCCCCCCCCCCCCC | 39.53 | 24489116 | |
| 721 | Ubiquitination | TLPPTIFKPYPLWTG ECCCCCCCCCCCCCC | 39.53 | 17644757 | |
| 729 | Ubiquitination | PYPLWTGKQIITTVL CCCCCCCCCEEEEEE | 30.83 | 17644757 | |
| 754 | Ubiquitination | INLISKNKIKNEYWG CCEEECCCCCCCCCC | 59.81 | 17644757 | |
| 756 | Acetylation | LISKNKIKNEYWGKG EEECCCCCCCCCCCC | 45.39 | 24489116 | |
| 756 | Ubiquitination | LISKNKIKNEYWGKG EEECCCCCCCCCCCC | 45.39 | 17644757 | |
| 762 | Ubiquitination | IKNEYWGKGSLENEV CCCCCCCCCCCCCEE | 31.05 | 17644757 | |
| 772 | Ubiquitination | LENEVLFKDGALLCG CCCEEEECCCCEEEE | 51.60 | 17644757 | |
| 783 | Acetylation | LLCGILDKSQYGASK EEEECCCHHHCCHHH | 35.69 | 24489116 | |
| 783 | Ubiquitination | LLCGILDKSQYGASK EEEECCCHHHCCHHH | 35.69 | 17644757 | |
| 790 | Acetylation | KSQYGASKYGIVHSL HHHCCHHHHCCCCCH | 47.14 | 24489116 | |
| 790 | Ubiquitination | KSQYGASKYGIVHSL HHHCCHHHHCCCCCH | 47.14 | 17644757 | |
| 808 | Ubiquitination | YGPEVAAKVLSVLGR HCHHHHHHHHHHHHH | 33.69 | 17644757 | |
| 841 | Ubiquitination | RLTAEGNKWRTDILK EEEECCCCCCHHHHH | 49.24 | 17644757 | |
| 848 | Acetylation | KWRTDILKTSVDTGR CCCHHHHHHHCCCCH | 38.80 | 24489116 | |
| 848 | Ubiquitination | KWRTDILKTSVDTGR CCCHHHHHHHCCCCH | 38.80 | 17644757 | |
| 866 | Acetylation | AEVTNLDKDTPADDP HHHHCCCCCCCCCCH | 67.67 | 24489116 | |
| 866 | Ubiquitination | AEVTNLDKDTPADDP HHHHCCCCCCCCCCH | 67.67 | 17644757 | |
| 877 | Acetylation | ADDPELLKRLQEILR CCCHHHHHHHHHHHH | 64.78 | 24489116 | |
| 877 | Ubiquitination | ADDPELLKRLQEILR CCCHHHHHHHHHHHH | 64.78 | 17644757 | |
| 888 | Ubiquitination | EILRDNNKSGILDAV HHHHHCCCCCHHHHH | 57.21 | 17644757 | |
| 889 | Phosphorylation | ILRDNNKSGILDAVT HHHHCCCCCHHHHHH | 32.94 | 28889911 | |
| 899 | Ubiquitination | LDAVTSSKVNAITSQ HHHHHHHHHHHHHHH | 39.00 | 24961812 | |
| 910 | Ubiquitination | ITSQVVSKCVPDGTM HHHHHHHHHCCCCCC | 27.86 | 17644757 | |
| 918 | Ubiquitination | CVPDGTMKKFPCNSM HCCCCCCCEECCCHH | 51.61 | 17644757 | |
| 919 | Ubiquitination | VPDGTMKKFPCNSMQ CCCCCCCEECCCHHH | 43.65 | 17644757 | |
| 924 | Phosphorylation | MKKFPCNSMQAMALS CCEECCCHHHHHHHH | 20.98 | 19823750 | |
| 931 | Phosphorylation | SMQAMALSGAKGSNV HHHHHHHHCCCCCCC | 27.45 | 19795423 | |
| 934 | Ubiquitination | AMALSGAKGSNVNVS HHHHHCCCCCCCCHH | 67.41 | 17644757 | |
| 936 | Phosphorylation | ALSGAKGSNVNVSQI HHHCCCCCCCCHHHH | 36.58 | 28889911 | |
| 941 | Phosphorylation | KGSNVNVSQIMCLLG CCCCCCHHHHHHHHC | 14.58 | 28889911 | |
| 964 | Ubiquitination | VPVMVSGKTLPSFKP CCEEEECCCCCCCCC | 39.11 | 17644757 | |
| 970 | Acetylation | GKTLPSFKPYETDAM CCCCCCCCCCCCCCC | 51.53 | 24489116 | |
| 970 | Ubiquitination | GKTLPSFKPYETDAM CCCCCCCCCCCCCCC | 51.53 | 17644757 | |
| 983 | Ubiquitination | AMAGGYVKGRFYSGI CCCCCEECCEEECCC | 35.57 | 17644757 | |
| 991 | Ubiquitination | GRFYSGIKPQEYYFH CEEECCCCCHHEEEE | 44.14 | 17644757 | |
| 1012 | Ubiquitination | GLIDTAVKTSRSGYL CCCCHHHHHCCCHHH | 38.02 | 17644757 | |
| 1059 | Ubiquitination | GDAIDITKESHMTQF CCCEECCCHHCCHHH | 58.51 | 17644757 | |
| 1078 | Ubiquitination | DNYYALLKKYNPSAL HHHHHHHHHHCHHHH | 54.80 | 17644757 | |
| 1079 | Ubiquitination | NYYALLKKYNPSALI HHHHHHHHHCHHHHH | 50.67 | 17644757 | |
| 1096 | Acetylation | LDVESALKYSKKTLK CCHHHHHHHCHHHHH | 47.39 | 24489116 | |
| 1096 | Ubiquitination | LDVESALKYSKKTLK CCHHHHHHHCHHHHH | 47.39 | 17644757 | |
| 1115 | Ubiquitination | HSKEPHYKQSVKYDP CCCCCCCCCCCCCCH | 32.82 | 17644757 | |
| 1119 | Acetylation | PHYKQSVKYDPVLAK CCCCCCCCCCHHHHH | 49.54 | 24489116 | |
| 1119 | Ubiquitination | PHYKQSVKYDPVLAK CCCCCCCCCCHHHHH | 49.54 | 17644757 | |
| 1126 | Acetylation | KYDPVLAKYNPAKYL CCCHHHHHCCHHHHH | 41.20 | 24489116 | |
| 1126 | Ubiquitination | KYDPVLAKYNPAKYL CCCHHHHHCCHHHHH | 41.20 | 17644757 | |
| 1131 | Ubiquitination | LAKYNPAKYLGSVSE HHHCCHHHHHCCCCH | 42.12 | 17644757 | |
| 1143 | Ubiquitination | VSENFQDKLESFLDK CCHHHHHHHHHHHHH | 43.29 | 17644757 | |
| 1150 | Ubiquitination | KLESFLDKNSKLFKS HHHHHHHHCCHHHHC | 66.33 | 17644757 | |
| 1164 | Acetylation | SSDGVNEKKFRALMQ CCCCCCHHHHHHHHH | 52.59 | 24489116 | |
| 1173 | Acetylation | FRALMQLKYMRSLIN HHHHHHHHHHHHHCC | 21.80 | 24489116 | |
| 1173 | Ubiquitination | FRALMQLKYMRSLIN HHHHHHHHHHHHHCC | 21.80 | 15699485 | |
| 1234 | Ubiquitination | MTASAAIKTPQMTLP HHHHHHCCCCCCCCC | 49.80 | 17644757 | |
| 1256 | Ubiquitination | EQADTFCKSISKVLL HHHHHHHHHHHHHHH | 46.78 | 23749301 | |
| 1260 | Ubiquitination | TFCKSISKVLLSEVI HHHHHHHHHHHHHHC | 34.92 | 17644757 | |
| 1264 | Phosphorylation | SISKVLLSEVIDKVI HHHHHHHHHHCCEEE | 26.17 | 20377248 | |
| 1269 | Ubiquitination | LLSEVIDKVIVTETT HHHHHCCEEEEEECC | 23.80 | 17644757 | |
| 1337 | Ubiquitination | VKEIKKQKRTTGPDI HHHHHHCCCCCCCCC | 61.67 | 17644757 | |
| 1340 | Phosphorylation | IKKQKRTTGPDIGVA HHHCCCCCCCCCCCC | 51.23 | 27017623 | |
| 1353 | Phosphorylation | VAVPRLQTDVANSSS CCHHCCCCCCCCCCC | 36.71 | 30377154 | |
| 1358 | Phosphorylation | LQTDVANSSSNSKRL CCCCCCCCCCCCCCC | 25.96 | 22369663 | |
| 1359 | Phosphorylation | QTDVANSSSNSKRLE CCCCCCCCCCCCCCC | 33.09 | 22369663 | |
| 1360 | Phosphorylation | TDVANSSSNSKRLEE CCCCCCCCCCCCCCC | 44.97 | 29734811 | |
| 1362 | Phosphorylation | VANSSSNSKRLEEDN CCCCCCCCCCCCCCC | 22.54 | 22369663 | |
| 1363 | Ubiquitination | ANSSSNSKRLEEDND CCCCCCCCCCCCCCC | 66.31 | 23749301 | |
| 1376 | Ubiquitination | NDEEQSHKKTKQAVS CCHHHHHHHHHHHCC | 68.34 | 17644757 | |
| 1377 | Ubiquitination | DEEQSHKKTKQAVSY CHHHHHHHHHHHCCC | 56.37 | 17644757 | |
| 1379 | Ubiquitination | EQSHKKTKQAVSYDE HHHHHHHHHHCCCCC | 45.18 | 23749301 | |
| 1383 | Phosphorylation | KKTKQAVSYDEPDED HHHHHHCCCCCCCHH | 29.86 | 27017623 | |
| 1409 | Phosphorylation | SDEEGIDSDKESDSD CCCCCCCCCCCCCCC | 48.97 | 21551504 | |
| 1413 | Phosphorylation | GIDSDKESDSDSEDE CCCCCCCCCCCCCCC | 48.43 | 16445868 | |
| 1415 | Phosphorylation | DSDKESDSDSEDEDV CCCCCCCCCCCCCCC | 52.92 | 16445868 | |
| 1417 | Phosphorylation | DKESDSDSEDEDVDM CCCCCCCCCCCCCCH | 51.39 | 16445868 | |
| 1430 | Ubiquitination | DMNEQINKSIVEANN CHHHHHHHHHHHHCH | 43.09 | 17644757 | |
| 1431 | Phosphorylation | MNEQINKSIVEANNN HHHHHHHHHHHHCHH | 27.64 | 22369663 | |
| 1441 | Ubiquitination | EANNNMNKVQRDRQS HHCHHHCHHHHHHHH | 29.04 | 17644757 | |
| 1459 | Acetylation | SHHRFITKYNFDDES HCCCEEEECCCCCCC | 33.12 | 24489116 | |
| 1482 | Ubiquitination | ELAADTEKLLMVNIV EECCCCHHHHHHHHH | 49.35 | 17644757 | |
| 1495 | Ubiquitination | IVEEICRKSIIRQIP HHHHHHHHHHHHHCC | 41.41 | 17644757 | |
| 1551 | Ubiquitination | NDVAAVLKTYGVEAA HHHHHHHHHHCHHHH | 32.85 | 15699485 | |
| 1578 | Phosphorylation | SRYAISVSFRHLDLI HHHHHEEHHHHHHHH | 15.12 | 27214570 | |
| 1605 | Phosphorylation | FNRQGMETSTSSFMK ECCCCCCCCCHHHHH | 28.54 | 27017623 | |
| 1606 | Phosphorylation | NRQGMETSTSSFMKM CCCCCCCCCHHHHHC | 17.00 | 27017623 | |
| 1607 | Phosphorylation | RQGMETSTSSFMKMS CCCCCCCCHHHHHCC | 35.49 | 27017623 | |
| 1612 | Ubiquitination | TSTSSFMKMSYETTC CCCHHHHHCCHHHHH | 23.76 | 17644757 | |
| 1615 | Phosphorylation | SSFMKMSYETTCQFL HHHHHCCHHHHHHHH | 17.50 | 27017623 | |
| 1623 | Phosphorylation | ETTCQFLTKAVLDNE HHHHHHHHHHHHHCH | 20.46 | 27017623 | |
| 1624 | Ubiquitination | TTCQFLTKAVLDNER HHHHHHHHHHHHCHH | 38.35 | 17644757 | |
| 1636 | Phosphorylation | NEREQLDSPSARIVV CHHHHCCCCCCEEEE | 29.37 | 17330950 | |
| 1638 | Phosphorylation | REQLDSPSARIVVGK HHHCCCCCCEEEEEE | 33.85 | 24961812 | |
| 1645 | Ubiquitination | SARIVVGKLNNVGTG CCEEEEEECCCCCCC | 36.11 | 17644757 | |
| 1651 | Phosphorylation | GKLNNVGTGSFDVLA EECCCCCCCCCEEEE | 25.93 | 30377154 | |
| 1653 | Phosphorylation | LNNVGTGSFDVLAKV CCCCCCCCCEEEECC | 20.36 | 30377154 | |
| 1659 | Ubiquitination | GSFDVLAKVPNAA-- CCCEEEECCCCCC-- | 54.81 | 17644757 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RPA1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RPA1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RPA1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1431 AND SER-1636, ANDMASS SPECTROMETRY. | |
| "Phosphoproteome analysis by mass spectrometry and its application toSaccharomyces cerevisiae."; Ficarro S.B., McCleland M.L., Stukenberg P.T., Burke D.J., Ross M.M.,Shabanowitz J., Hunt D.F., White F.M.; Nat. Biotechnol. 20:301-305(2002). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1413; SER-1415 ANDSER-1417, AND MASS SPECTROMETRY. | |
