| UniProt ID | VPS29_YEAST | |
|---|---|---|
| UniProt AC | P38759 | |
| Protein Name | Vacuolar protein sorting-associated protein 29 | |
| Gene Name | VPS29 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 282 | |
| Subcellular Localization | ||
| Protein Description | Plays a role in vesicular protein sorting. Required for the endosome-to-Golgi retrieval of the vacuolar protein sorting receptor VPS10. Component of the membrane-associated retromer complex which is essential in endosome-to-Golgi retrograde transport. The VPS29-VPS26-VPS35 subcomplex may be involved in cargo selection.. | |
| Protein Sequence | MLLLALSDAHIPDRATDLPVKFKKLLSVPDKISQVALLGNSTKSYDFLKFVNQISNNITIVRGEFDNGHLPSTKKDKASDNSRPMEEIPMNSIIRQGALKIGCCSGYTVVPKNDPLSLLALARQLDVDILLWGGTHNVEAYTLEGKFFVNPGSCTGAFNTDWPIVFDVEDSDEAVTSEVDKPTKENQSEDDDAKGGSTGKEQPGSYTPKEGTAGERENENESNVKPENQFKEDEVDMSDSDINGSNSPSFCLLDIQGNTCTLYIYLYVNGEVKVDKVVYEKE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 21 | Acetylation | RATDLPVKFKKLLSV CCCCCCCCHHHHCCC | 49.91 | 24489116 | |
| 31 | Ubiquitination | KLLSVPDKISQVALL HHCCCCCCCCEEEHH | 37.88 | 23749301 | |
| 31 | Acetylation | KLLSVPDKISQVALL HHCCCCCCCCEEEHH | 37.88 | 24489116 | |
| 42 | Phosphorylation | VALLGNSTKSYDFLK EEHHCCCCCHHHHHH | 28.19 | 24909858 | |
| 43 | Acetylation | ALLGNSTKSYDFLKF EHHCCCCCHHHHHHH | 47.00 | 24489116 | |
| 171 | Phosphorylation | IVFDVEDSDEAVTSE EEEECCCCCHHCCCC | 24.68 | 21440633 | |
| 176 | Phosphorylation | EDSDEAVTSEVDKPT CCCCHHCCCCCCCCC | 26.64 | 21551504 | |
| 183 | Phosphorylation | TSEVDKPTKENQSED CCCCCCCCCCCCCCC | 57.65 | 21440633 | |
| 188 | Phosphorylation | KPTKENQSEDDDAKG CCCCCCCCCCCCCCC | 55.35 | 27214570 | |
| 205 | Phosphorylation | TGKEQPGSYTPKEGT CCCCCCCCCCCCCCC | 32.30 | 22369663 | |
| 206 | Phosphorylation | GKEQPGSYTPKEGTA CCCCCCCCCCCCCCC | 32.74 | 22369663 | |
| 207 | Phosphorylation | KEQPGSYTPKEGTAG CCCCCCCCCCCCCCC | 29.58 | 22369663 | |
| 212 | Phosphorylation | SYTPKEGTAGERENE CCCCCCCCCCCCCCC | 32.36 | 29136822 | |
| 222 | Phosphorylation | ERENENESNVKPENQ CCCCCCCCCCCHHHC | 59.51 | 29136822 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of VPS29_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of VPS29_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of VPS29_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-207, AND MASSSPECTROMETRY. | |
