| UniProt ID | SED5_YEAST | |
|---|---|---|
| UniProt AC | Q01590 | |
| Protein Name | Integral membrane protein SED5 | |
| Gene Name | SED5 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 340 | |
| Subcellular Localization |
Membrane Single-pass type IV membrane protein . Golgi apparatus membrane Single-pass type IV membrane protein . |
|
| Protein Description | Required for vesicular transport between the endoplasmic reticulum and the Golgi complex. Acts as a target organelle soluble NSF attachment protein receptor (t-SNARE).. | |
| Protein Sequence | MNIKDRTSEFQQSVLSYKKRNKNFREQQRERLQEKESENFANNTTGNGKSVSEFQKKASGIAHEISSTAQLLSKLAVLAKRKPMFNDNPVEIAELSFLIKRKIYAIEQSLVQLSQLKKTDVNGNTSNQSSKQPSAVQHSKNVVNLLNTQMKNISGSFKDVLEERQRLEMANKDRWQKLTTDTGHAPADDQTQSNHAADLTTYNNSNPFMTSLLDESSEKNNNSSNQGELSFPQNDSQLMLMEEGQLSNNVYLQERNRAVETIESTIQEVGNLFQQLASMVQEQGEVIQRIDANVDDIDLNISGAQRELLKYFDRIKSNRWLAAKVFFIIFVFFVIWVLVN | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 18 | Acetylation | QQSVLSYKKRNKNFR HHHHHHHHHHCCCHH | 41.71 | 24489116 | |
| 35 | Ubiquitination | QRERLQEKESENFAN HHHHHHHHHHHHCCC | 54.29 | 23749301 | |
| 37 | Phosphorylation | ERLQEKESENFANNT HHHHHHHHHHCCCCC | 49.24 | 28889911 | |
| 49 | Ubiquitination | NNTTGNGKSVSEFQK CCCCCCCCCHHHHHH | 52.24 | 23749301 | |
| 52 | Phosphorylation | TGNGKSVSEFQKKAS CCCCCCHHHHHHHHH | 39.52 | 27017623 | |
| 56 | Ubiquitination | KSVSEFQKKASGIAH CCHHHHHHHHHCCCH | 56.48 | 17644757 | |
| 57 | Ubiquitination | SVSEFQKKASGIAHE CHHHHHHHHHCCCHH | 36.68 | 17644757 | |
| 59 | Phosphorylation | SEFQKKASGIAHEIS HHHHHHHHCCCHHHH | 39.34 | 27017623 | |
| 74 | Ubiquitination | STAQLLSKLAVLAKR HHHHHHHHHHHHHHC | 40.20 | 17644757 | |
| 102 | Ubiquitination | LSFLIKRKIYAIEQS HHHHHHHHHHHHHHH | 34.76 | 17644757 | |
| 117 | Ubiquitination | LVQLSQLKKTDVNGN HHHHHHHCCCCCCCC | 46.09 | 17644757 | |
| 118 | Ubiquitination | VQLSQLKKTDVNGNT HHHHHHCCCCCCCCC | 59.56 | 17644757 | |
| 140 | Acetylation | PSAVQHSKNVVNLLN CCHHHHHHHHHHHHH | 52.19 | 24489116 | |
| 151 | Ubiquitination | NLLNTQMKNISGSFK HHHHHHHHHCCCCHH | 41.11 | 24961812 | |
| 154 | Phosphorylation | NTQMKNISGSFKDVL HHHHHHCCCCHHHHH | 37.47 | 19779198 | |
| 158 | Ubiquitination | KNISGSFKDVLEERQ HHCCCCHHHHHHHHH | 48.93 | 24961812 | |
| 158 | Acetylation | KNISGSFKDVLEERQ HHCCCCHHHHHHHHH | 48.93 | 24489116 | |
| 217 | Phosphorylation | TSLLDESSEKNNNSS HHHHCCCHHHCCCCC | 51.01 | 21440633 | |
| 310 | Ubiquitination | GAQRELLKYFDRIKS HHHHHHHHHHHHHHC | 57.40 | 24961812 | |
| 310 | Acetylation | GAQRELLKYFDRIKS HHHHHHHHHHHHHHC | 57.40 | 24489116 | |
| 317 | Phosphorylation | KYFDRIKSNRWLAAK HHHHHHHCCHHHHHH | 29.29 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
| 8 | S | Phosphorylation | Kinase | PKA-FAMILY | - | GPS |
| 317 | S | Phosphorylation | Kinase | PKA-FAMILY | - | GPS |
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SED5_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SED5_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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