UniProt ID | YPT31_YEAST | |
---|---|---|
UniProt AC | P38555 | |
Protein Name | GTP-binding protein YPT31/YPT8 | |
Gene Name | YPT31 | |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
Sequence Length | 223 | |
Subcellular Localization |
Golgi apparatus membrane Lipid-anchor . |
|
Protein Description | Required for protein transport in the secretory pathway. Probably involved in regulation of secretory vesicle formation at the trans-Golgi compartment. Plays a role in autophagy.. | |
Protein Sequence | MSSEDYGYDYDLLFKIVLIGDSGVGKSNLLSRFTKNEFNMDSKSTIGVEFATRTLEIDGKRIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDISKSSSYENCNHWLSELRENADDNVAVGLIGNKSDLAHLRAVPTEESKTFAQENQLLFTETSALNSENVDKAFEELINTIYQKVSKHQMDLGDSSANGNANGASAPNGPTISLTPTPNENKKANGNNCC | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
|
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
2 | Phosphorylation | ------MSSEDYGYD ------CCHHHHCCC | 42.29 | 28152593 | |
2 | Acetylation | ------MSSEDYGYD ------CCHHHHCCC | 42.29 | - | |
3 | Phosphorylation | -----MSSEDYGYDY -----CCHHHHCCCH | 32.94 | 19823750 | |
26 | Ubiquitination | IGDSGVGKSNLLSRF ECCCCCCHHHHHHHH | 33.49 | 23749301 | |
35 | Acetylation | NLLSRFTKNEFNMDS HHHHHHCCCCCCCCC | 52.33 | 24489116 | |
35 | Ubiquitination | NLLSRFTKNEFNMDS HHHHHHCCCCCCCCC | 52.33 | 23749301 | |
44 | Phosphorylation | EFNMDSKSTIGVEFA CCCCCCCCCEEEEEC | 29.25 | 22369663 | |
45 | Phosphorylation | FNMDSKSTIGVEFAT CCCCCCCCEEEEECE | 26.03 | 22369663 | |
63 | Ubiquitination | EIDGKRIKAQIWDTA EECCEEEEEEEECCC | 37.97 | 23749301 | |
80 | Phosphorylation | ERYRAITSAYYRGAV HHHHHHHHHHHHCCC | 14.25 | 27214570 | |
127 | Ubiquitination | AVGLIGNKSDLAHLR EEEEECCHHHHHHHC | 39.88 | 24961812 | |
138 | Phosphorylation | AHLRAVPTEESKTFA HHHCCCCCHHHHHHH | 45.87 | 21440633 | |
177 | Acetylation | LINTIYQKVSKHQMD HHHHHHHHHHHHCCC | 31.35 | 24489116 | |
180 | Acetylation | TIYQKVSKHQMDLGD HHHHHHHHHCCCCCC | 40.62 | 24489116 | |
188 | Phosphorylation | HQMDLGDSSANGNAN HCCCCCCCCCCCCCC | 29.56 | 23749301 | |
189 | Phosphorylation | QMDLGDSSANGNANG CCCCCCCCCCCCCCC | 30.41 | 21551504 | |
198 | Phosphorylation | NGNANGASAPNGPTI CCCCCCCCCCCCCEE | 45.73 | 21551504 | |
204 | Phosphorylation | ASAPNGPTISLTPTP CCCCCCCEEECCCCC | 25.29 | 23749301 | |
206 | Phosphorylation | APNGPTISLTPTPNE CCCCCEEECCCCCCC | 28.77 | 24961812 | |
208 | Phosphorylation | NGPTISLTPTPNENK CCCEEECCCCCCCCC | 20.51 | 23749301 | |
210 | Phosphorylation | PTISLTPTPNENKKA CEEECCCCCCCCCCC | 33.25 | 21440633 | |
222 | Geranylgeranylation | KKANGNNCC------ CCCCCCCCC------ | 3.19 | - | |
223 | Geranylgeranylation | KANGNNCC------- CCCCCCCC------- | 7.31 | - |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of YPT31_YEAST !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of YPT31_YEAST !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of YPT31_YEAST !! |
Kegg Drug | ||||||
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DrugBank | ||||||
There are no disease associations of PTM sites. |
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Phosphorylation | |
Reference | PubMed |
"A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-44 AND THR-45, AND MASSSPECTROMETRY. |