TMA23_YEAST - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TMA23_YEAST
• UniProt AC: Q03525
• Protein Name: Protein TMA23
• Gene Name: TMA23
• Organism: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
• Sequence Length: 211
• Subcellular Localization: Nucleus, nucleolus .
• Protein Description: Trans-acting factors of the ribosome biogenesis process..
• Protein Sequence: MDSKEYLISYGWKEGEAFREGGLKRPILVKHKRDKKGLGNAPGGNDGEAWWERLFDGHLKNLDVSTDSNNGSIKFTQNEAVATAVSKSSSPLYRWFVKGEGLKGTITNLGKKEEASFVVSSASSSKGKKRRRRDEDDNKVKRKKLKKDKKTSNDSESKKKKKKKSKKESKKGKKSKHSSDEGDKSKHKKSKKSKKHKKEESSARRDRKEHI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MDSKEYLISY -----CCCHHHHHHC	26.53	30377154
30	Acetylation	LKRPILVKHKRDKKG CCCCEEEEECCCCCC	39.71	25381059
68	Phosphorylation	NLDVSTDSNNGSIKF CEEECCCCCCCEEEE	32.08	30377154
72	Phosphorylation	STDSNNGSIKFTQNE CCCCCCCEEEEECCH	25.40	30377154
90	Phosphorylation	TAVSKSSSPLYRWFV HHHHCCCCCCCHHHH	26.47	21440633
178	Phosphorylation	KGKKSKHSSDEGDKS HCCCCCCCCCCCCHH	43.13	19795423
179	Phosphorylation	GKKSKHSSDEGDKSK CCCCCCCCCCCCHHH	39.13	19795423
201	Phosphorylation	KKHKKEESSARRDRK HHHHHHHHHHHHHHH	30.32	27717283
202	Phosphorylation	KHKKEESSARRDRKE HHHHHHHHHHHHHHH	29.13	27717283

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TMA23_YEAST !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TMA23_YEAST !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TMA23_YEAST !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EI2BA_YEAST	GCN3	physical	10688190
DOHH_YEAST	LIA1	genetic	17425675
RRP8_YEAST	RRP8	genetic	19061648
EIF3J_YEAST	HCR1	genetic	19061648
MRM2_YEAST	MRM2	genetic	19061648
IF2A_YEAST	SUI2	genetic	19061648
NMD5_YEAST	NMD5	genetic	19061648
LTV1_YEAST	LTV1	genetic	19061648
FKBP_YEAST	FPR1	genetic	19061648
ECM8_YEAST	ECM8	genetic	20093466
RU1A_YEAST	MUD1	genetic	20093466
DPB3_YEAST	DPB3	genetic	20093466
BUD31_YEAST	BUD31	genetic	20093466
RMD1_YEAST	RMD1	genetic	20093466
RRP8_YEAST	RRP8	genetic	20093466
EAF1_YEAST	EAF1	genetic	20093466
AK_YEAST	HOM3	genetic	20093466
UBP6_YEAST	UBP6	genetic	20093466
RL29_YEAST	RPL29	genetic	20093466
HXKA_YEAST	HXK1	genetic	20093466
CTU1_YEAST	NCS6	genetic	20093466
SSF1_YEAST	SSF1	genetic	20093466
COPE_YEAST	SEC28	genetic	20093466
IST3_YEAST	IST3	genetic	20093466
SDHA_YEAST	SDH1	genetic	20093466
DBP7_YEAST	DBP7	genetic	20093466
LDB18_YEAST	LDB18	genetic	20093466
SIC1_YEAST	SIC1	genetic	20093466
LSM7_YEAST	LSM7	genetic	20093466
CYP8_YEAST	CPR8	genetic	20093466
REXO4_YEAST	REX4	genetic	20093466
NOP12_YEAST	NOP12	genetic	20093466
RU2A_YEAST	LEA1	genetic	20093466
SUR1_YEAST	SUR1	genetic	20093466
PMA2_YEAST	PMA2	genetic	20093466
BUD31_YEAST	BUD31	genetic	27708008
INO4_YEAST	INO4	genetic	27708008
MAF1_YEAST	MAF1	genetic	27708008
RRP8_YEAST	RRP8	genetic	27708008
NUM1_YEAST	NUM1	genetic	27708008
LSM6_YEAST	LSM6	genetic	27708008
RL29_YEAST	RPL29	genetic	27708008
MAL12_YEAST	MAL12	genetic	27708008
SSF1_YEAST	SSF1	genetic	27708008
DBP7_YEAST	DBP7	genetic	27708008
SIC1_YEAST	SIC1	genetic	27708008
RSA3_YEAST	RSA3	genetic	27708008
LSM7_YEAST	LSM7	genetic	27708008
NOP12_YEAST	NOP12	genetic	27708008
REXO4_YEAST	REX4	genetic	27708008
YO098_YEAST	YOL098C	genetic	27708008
SUR1_YEAST	SUR1	genetic	27708008

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.