| UniProt ID | SSF1_YEAST | |
|---|---|---|
| UniProt AC | P38789 | |
| Protein Name | Ribosome biogenesis protein SSF1 | |
| Gene Name | SSF1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 453 | |
| Subcellular Localization | Nucleus, nucleolus . | |
| Protein Description | Required for biogenesis of the 60S ribosomal subunit.. | |
| Protein Sequence | MAKRRQKKRTHAQLTPEQEQGIPKSMVIRVGQTSLANHSLNQLVKDFRQIMQPHTAIKLKERKSNKLKDFVVMCGPLGVTHLFMFTQSEKTGNVSLKIARTPQGPTVTFQVLDYSLGRDIKKFLKRPKSLNNDDVLNPPLLVLNGFSTSKRSGEDDQDVNVEKVIVSMFQNIFPPLNPARTSLNSIKRVFMINKDRETGEISMRHYFIDIREVEISRNLKRLYKAKNNLSKTVPNLHRKEDISSLILDHDLGAYTSESEIEDDAIVRVVDNQDVKAKHSQSLKSQRTPVEKKDNKEREKETEEEDVEMEEPKPSENLQPTPRKKAIKLTELGPRLTLKLVKIEEGICSGKVLHHEFVQKSSEEIKALEKRHAAKMRLKEQRKKEQEENIAKKKAVKDAKKQRKLERRKARAAEGGEGQGKDDAMSDDESSSSDSEHYGSVPEDLDSDLFSEVE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 15 | Phosphorylation | KRTHAQLTPEQEQGI HHCCCCCCHHHHCCC | 16.82 | 25752575 | |
| 24 | Ubiquitination | EQEQGIPKSMVIRVG HHHCCCCHHHEEEEC | 49.62 | 17644757 | |
| 45 | Acetylation | HSLNQLVKDFRQIMQ CCHHHHHHHHHHHHC | 60.79 | 24489116 | |
| 45 | Ubiquitination | HSLNQLVKDFRQIMQ CCHHHHHHHHHHHHC | 60.79 | 17644757 | |
| 231 | Acetylation | KAKNNLSKTVPNLHR HHHHCHHCCCCCCCC | 57.62 | 24489116 | |
| 243 | Phosphorylation | LHRKEDISSLILDHD CCCCCCHHHHHHCCC | 31.26 | 19779198 | |
| 244 | Phosphorylation | HRKEDISSLILDHDL CCCCCHHHHHHCCCC | 21.55 | 19779198 | |
| 254 | Phosphorylation | LDHDLGAYTSESEIE HCCCCCCCCCCCCCC | 14.70 | 17330950 | |
| 255 | Phosphorylation | DHDLGAYTSESEIED CCCCCCCCCCCCCCC | 26.03 | 19795423 | |
| 256 | Phosphorylation | HDLGAYTSESEIEDD CCCCCCCCCCCCCCC | 26.84 | 17330950 | |
| 258 | Phosphorylation | LGAYTSESEIEDDAI CCCCCCCCCCCCCCE | 43.57 | 17330950 | |
| 283 | Acetylation | AKHSQSLKSQRTPVE HHHCCCHHHCCCCCC | 50.19 | 25381059 | |
| 301 | Phosphorylation | NKEREKETEEEDVEM HHHHHHHHHHHHCCC | 60.82 | 17330950 | |
| 329 | Phosphorylation | RKKAIKLTELGPRLT CHHHCHHHCCCCCEE | 24.94 | 23749301 | |
| 338 | Ubiquitination | LGPRLTLKLVKIEEG CCCCEEEEEEEECCC | 46.10 | 15699485 | |
| 341 | Ubiquitination | RLTLKLVKIEEGICS CEEEEEEEECCCCCC | 55.63 | 15699485 | |
| 350 | Ubiquitination | EEGICSGKVLHHEFV CCCCCCCCHHCHHHH | 25.90 | 15699485 | |
| 359 | Ubiquitination | LHHEFVQKSSEEIKA HCHHHHHCCHHHHHH | 51.12 | 15699485 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SSF1_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SSF1_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SSF1_YEAST !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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| Phosphorylation | |
| Reference | PubMed |
| "A multidimensional chromatography technology for in-depthphosphoproteome analysis."; Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; Mol. Cell. Proteomics 7:1389-1396(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-301, AND MASSSPECTROMETRY. | |
| "Large-scale phosphorylation analysis of alpha-factor-arrestedSaccharomyces cerevisiae."; Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,Elias J.E., Gygi S.P.; J. Proteome Res. 6:1190-1197(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-301, AND MASSSPECTROMETRY. | |
